India is a country of immense diversity. It is home to people of many different racial, languages, ethnic, religious, and national backgrounds. Groups of people in India differ from each other not only in physical or demographic characteristics but also in distinctive patterns of behavior and these patterns are determined by social and cultural factors like language, region, religion, and caste. Apart from behaviour, economic development, level of education and political culture of the people in various social segments differ from region to region. More you can say that economy and cultures have been enriched by the contributions of migrants from round the globe. In an increasingly globalised world, migratory movements is continuously shaping the countries all over the world. Some countries like India and Ireland, which set the example of economic development and social integration, have the positive impact of the migration by globalisation and some countries like USA, which recently witness racism, xenophobia and discrimination have the negative impact on the migrants. It does not mean India do not face fragmentation and USA do not have cohesion. USA have many stories which show successful integration process, that facilitated the lives of immigrant communities, but being a developed country it still suffers from cultural alienation. In these countries, borders are built within borders to create cultural divides that do not allow people to integrate. Recently, this problem has become more prominent due to the rise of terrorism, clash of cultures in the world, leading to the glorification of stereotypes. People are becoming less accepting towards anyone who does not belong to their region. Migration does not stop after people move from one place to another place. The main question start after that ‘now what’ they will do. That is why this topic needs to be discussed thoroughly in order to find better solutions. This paper will begin with an analysis of different approaches to Migration, discuss the target groups for integration policies, provide indicators of the current situation of migrants and proceed to an analysis of integration tools: legislation, social policies and participatory processes. It will focus not only on the impact of migration but also on social integration, mix culture like indo-western culture in a comparative basis.

Ekta meena

Crude methanol extracts of the leaves of Adenanthera pavonina L., Peltoforum roxburghii L, Prosopis cineraria L., and Prosopis juliflora DC., were evaluated for anti-emetic activity. Emesis was induced by the oral administration of copper sulphate 50mg/kg body weight to male chicks of four days age. The anti-emetic activity was determined by calculating the mean decrease in number of retching in contrast with those of control. All extracts (150 mg / kg body weight orally) showed anti-emetic activity when compared with standard drug Chlorpromazine at the same dose. Among all the extracts, Prosopis juliflora showed the highest (73.64%) and Adenanthera pavonina showed the lowest (50.17%) anti-emetic activity

Dr. salman ahmed

Pain according to WHO has been one of the greatest issues to plague man, in the bid to handle this issue of pain, man has sought to look for other means to reduce pain to its bare minimum. This study is aimed at investigating the analgesic activity of the methanolic extract of the African weaver ant using acetic acid-induced writhing, hot plate method, and formalin-induced pain models in Swiss mice. In the acetic acid test, the methanolic extract of Oecophylla longinoda (OL) was administered orally at 200 and 400 mg/kg body weight while aspirin was administered at 100 mg/kg and tween 80 served as standards. In the hot plate and formalin models, the extract was administered orally at two doses of 200 and 400 mg/kg while pentazocine at 10 mg/kg and tween 80 at 10 mg/kg served as standards. The methanolic extract of OL exhibited significant analgesic activity in all the models, with none less than the standard significant difference (p < 0.05) by increasing the reaction time of the mice after treatment in comparison to the control. The 400 mg/kg extract in the acetic acid-induced writhing response has a percentage inhibition of 52.7%, which shows how well the extract inhibits pain in mice. The methanolic extract significantly reduced pain response in mice, with a p-value of 0.03, 0.02, and 0.001 in all the test models, respectively. OL increased the pain threshold over time and significantly reduced the writhing response that mice experience from acetic acid. Furthermore, pretreatment with OL significantly and dose-dependently decreased the early and late phases of formalin-induced pain in mice. Thus, these findings suggest that the methanolic extract of OL acts on central and peripheral pain pathways.

Mediterranean journal of pharmacy and pharmaceutical sciences

PKN Subject is on one of lesson implemented on SD, SMP and SMA to apply student characters and to form the student to understand and love home land also understand global life. The research background of the low student achievement on study still using lecture method, giving assignments, answer and guestion on PKN subject. The purposes of this research: 1.how student achievement on PKN subject before using word sguare model. 2. How student achievement on PKN subject after using calassroom action rescarch with quantitative approach. The sample is the students of class III MIS NU 2 Pontianak.in order to get the data, researcher using observation shett, measurement technique and documentation study.The result concluded: 1.the student achievement before using word square model the average is 53 ( good category ) with KKM > 70 as 5 or 25% and students with KKM < 70 as 15 students or 75%. 2. The student achievement after using word square on cycle 1 is 68,5 ( Better category) with KKM 55%. On the other hands, cycle 11 is 82,5 (Great category ) with KKM 90%. Mata pelajaran PKn salah satu pelajaran yang diterapkan mulai dari SD, SMP dan SMA dengan membekali karakter dan membentuk peserta didik cinta tanah air dan paham dalam kehidupan yang serba global. Rumusan penelitian ini; 1) Bagaimanan hasil belajar siswa pada mata pelajaran pendidikan kewarganegaraan sebelum menggunakan model pembelajaran word square kelas 3 MIS NU 2 Pontianak. 2) Bagaimana hasil belajar siswa pada mata pelajaran pendidikan kewarganegaraan setelah menggunakan model pembelajaran word square kelas 3 MIS NU 2 Pontianak. Metode dan jenis penelitian ini menggunakan jenis penelitian tindakan kelas dengan pendekatan kuantitatif.Subjek penelitian ini adalah siswa kelas III MIS NU 2 Pontianak. Untuk mendapatkan data peneliti menggunakan lembar observasi, teknik pengukuran dan studi dokumentasi. Hasil dari penelitian ini yaitu: 1) Hasil belajar siswa pada Mata Pelajaran PKn sebelum menggunakan model pembelajaran Word Square diperoleh nilai rata-rata sebesar 53 (kategori cukup) dengan siswa yang tuntas mencapai nilai KKM ? 70 sebanyak 5 atau 25% dan siswa yang tidak tuntas dengan nilai KKM ? 70 sebanyak 15 siswa atau 75%. 2) Hasil belajar siswa pada Mata Pelajaran PKn setelah menggunakan model pembelajaran Word Square pada siklus I sebesar 68,5 (kategori baik) dan siswa yang mencapai KKM sebesar 55%. Sedangkan pada siklus II sebesar 82,5 (kategori sangat baik) dan siswa yang mencapai KKM sebesar 90.

Educare: journal of primary education

Madrasah Ibtidaiyah Unggulan Al-Islah Muncar Banyuwangi adalah sekolah swasta yang pada bulan Januari 2018 mulai menerapkan kegiatan ekstrakurikuler tari tradisional dengan alasan untuk mengembangkan salah satu potensi yang dimiliki peserta didik yaitu kecerdasan kinestetik. Fokus penelitian ini, yaitu: 1) Bagaimana pengembangan kecerdasan kinestetik peserta didik melalui kegiatan ekstrakurikuler unsur wiraga tari tradisional di Madrasah Ibtidaiyah Unggulan Al-Islah Kecamatan Muncar Kabupaten Banyuwangi tahun pelajaran 2018/2019? 2) Bagaimana pengembangan kecerdasan kinestetik peserta didik melalui kegiatan ekstrakurikuler unsur wirama tari tradisional di Madrasah Ibtidaiyah Unggulan Al-Islah Kecamatan Muncar Kabupaten Banyuwangi tahun pelajaran 2018/2019? 3) Bagaimana pengembangan kecerdasan kinestetik peserta didik melalui kegiatan ekstrakurikuler unsur wirasa tari tradisional di Madrasah Ibtidaiyah Unggulan Al-Islah Kecamatan Muncar Kabupaten Banyuwangi tahun pelajaran 2018/2019? Hasil penelitian menunjukkan bahwa: 1) Meliputi, dengan pengenalan gerak dasar tari, pembiasaan senam pemanasan, latihan gerakan-gerakan tari tradisional dan perkembangannya dapat menguasai bagian-bagian tubuh ketika menari. 2)Meliputi, mengatur cepat lambatnya gerakan menggunakan hitungan dan perasaan, mengatur antara pergantian gerakan disaat musik yang tepat dengan menggunakan hitungan, mengatur keselarasan antara pukulan musik dengan gerakan-gerakan agar terdengar lebih mantap dengan menggunakan hitungan dan perasaan, dan perkembangannya dapat menyeimbangkan gerakan tari dengan alunan musik. 3) Dengan pembiasaan senam senyum selama beberapa menit agar terbiasa berkspresi tersenyum ketika menari, dan perkembangannya dapat terbiasa berekspresi tersenyum ketika menari.

Educare: journal of primary education

2-Azetidinone shows biological activities like anti-bacterial, anti-microbial activity, anti-tubercular activity, and anti-cancer activity. 2-azetdinone derivatives were synthesized by simple procedures. The first step is synthesis of benzohydrazide through nucleophilic substitution reaction between methyl benzoate and hydrazine hydrate. The above formed compound is then treated with substituted aromatic aldehydes in the presence of catalytic amount of concentrated hydrochloric acid with stirring for one hour to give benzohydrazone which results in the formation of Schiff bases.Schiff bases undergone cyclisation in the presence of chloroacetylchloride and diethylenediamine by using ethanol as a solvent upon stirring for 4 hour’s yielded 2-azetidinone derivatives. The in-silico anti-leukemic activity was determined by using the computational tools i.e. “PASS Online”, “AutoDock4.2” and “ADMET” properties by online software’s. Among these six derivatives compounds (AZT-6) was shown more activity when compared with the other five compounds.

M. yaswanth

Stakeholder plays significant roles in project success. They ensure clear communication of project goals, contribute to decision-making, and demonstrate commitment, increasing the likelihood of successful outcomes. They also act as advocates within their organizations, generating buy-in and support. The main purpose of this paper is to identify and discuss the roles of shareholders in a project success. The paper is conceptual in nature and uses a number literatures ranging from 2007 to 2023 from a good number of journals. After scrutinized the literature review, the paper concludes a number of findings. The findings implies that stakeholders in a project is crucial for its success and sustainability. Stakeholders play a significant role in ensuring the performance of the project. Project managers need to acquire stakeholder management skills to address the communication requirements of stakeholders. This is important for the success of the project. The paper recommend that policymakers, practitioners and academia have to ensure the expectations and make a balance among the stakeholders.

Nazim ullah

Autophagy is a self-digesting mechanism responsible for removal of damaged organelles, malformed proteins during biosynthesis, and nonfunctional long-lived proteins by lysosome. Autophagy has been divided into three general types depending on the mechanism by which intracellular materials are delivered into lysosome for degradation that is, microautophagy, chaperone-mediated autophagy (CMA), and macroautophagy. In microautophagy cytoplasm material is sequestered through direct invagination to the lysosomal membrane. Whereas in CMA proteins flagged with pentapeptide motif (KFERQ) were selectively degraded through direct translocation into lysosome. Macroautophagy involves the formation of subcellular double-membrane-bound structures called autophagosomes that contain degradable contents of cytoplasm materials and deliver them into lysosomes for breakdown by lysosomal enzymes. The molecular mechanism of autophagy involves several conserved Atg (autophagy-related) proteins. Systems produce modified complexes Atg8-PE and Atg5-Atg12-Atg16 as autophagy regulators. Autophagy is activated in response to diverse stress and physiological conditions. For example, food deprivation, hyperthermia, and hypoxia are mediated by factors like insulin/IGF-1, m-TOR signaling, FOXO transcription factors, and chaperones. The perturbance in autophagy may lead to several types of cancers, myopathies, and neuromuscular disorders. Several autophagy inducers and inhibitors like 3-methyladenine (3-MA), bafilomycin A1, LY294002 (LY), and Velcade have been used to treat disease is an intense field of study.

Kamal singh

Human being has some basic needs which include Food, Clothing & Shelter, in addition to above Healthcare, Education, Sanitation are also core part of basic necessities in modern society. In above mention basic necessities Healthcare facility was near to unavailable till independence for majority of citizens in country but this picture change dramatically with help of FDI allowed by Govt. of India. Foreign Direct Investment as a strategic element of funding is required in every develop & developing country. FDI inflows are long term in nature which causes source of non-debt finance, as well as bring modern & innovative technology in country by creating international network. In this paper, author attempted to discover how FDI is crucially impact on Indian Pharmaceutical Sectors progress by stimulating domestic investment & new employment opportunities, improving healthcare facilities to citizens in India. With the help of available relevant secondary data, a qualitative approach was followed for the study. It was found in study that the major factors responsible for attracting FDI in pharmaceutical sector are rise in outsourcing activities, demand in the generics market, demand from emerging segments, increase in domestic demand, large numbers of forthcoming patent expires. On the other hand Indian pharmaceutical industry is facing some challenges such as, low government expenditure on healthcare, poor healthcare infrastructure in rural areas, lack of proper Govt. policy to attract larger FDI in healthcare sector.

Anshuman vijay magar

About 12% of the world's population is affected by different forms of urolithiasis, of which the recurrence rate in females is 47–60% and in males is 70–80%. Standard therapeutic agents (allopurinol, citrate, cystone and thiazide diuretics) prevent and treat urolithiasis. Still, these are not universally-effective due to common kidney stone relapse and other side effects. Surgical treatment causes long-term renal damage, hypertension and stone recurrence. Polyphenols, the plant-derived bioactive molecules, have showed protection against cancers, cardiovascular diseases, diabetes, osteoporosis and neurodegenerative diseases, among several other ailments. The role of these phytochemicals in urolithiasis management is emerging. Hence, the present review discusses peer-reviewed published literature to date on this aspect and highlights that polyphenols could effectively inhibit the formation of calcium oxalate urinary stones (most common renal stone), correlating with their antioxidant, anti-inflammatory, diuretic and angiotensin-converting enzyme (ACE) inhibition. Further, we have proposed the prospects and challenges in developing plant polyphenols into drugs against kidney stone prevention. This review might be a stepping stone for further investigation into the clinical implications of polyphenols in urolithiasis remediation.

Dr. salman ahmed

Toxicity of different insecticides was evaluated against 2nd and 3rd instar larvae of Helicoverpa armigera under laboratory conditions by leaf dipping method. The insecticides viz., thiodicarb 75WP, novaluron 10EC, spinetroam 11.7EC, indoxacarb 15.8EC, quinalphos 25EC, rynaxypyr 18.5SC, emamectin benzoate 5SG and cypermethrin 25EC were tested. Spinetoram was found most effective in managing the 2nd instar larvae of H. armigera and it was followed by novaluron 10EC and indoxacarb 15.8EC as compared to cypermethrin 25EC. Emamectin benzoate 5SG @ 1 x 10-7 to 1 x 10-9 per cent concentrations recorded 100% mortality against 2nd instar larvae and LC50 values for 3rd instar larvae was 0.00000000045%. Insecticides novaluron 10EC, spinetoram 11.7EC and cypermethrin 25EC did not show promising and consistent results against 3rd instar larvae of H. armigera at 24 hrs. The LT50 of novaluron 10EC at 0.00005% concentration was 19.861 hrs and it was 28.144 hrs at 0.000001% against 2nd instar larvae of H. armigera

Dr. babu lal jat

n India, the education sector has been always attentive to adopt innovations and techniques in the teaching-learning process due to various challenges. But nowadays, academic institutions are becoming flexible in accepting the new teaching and learning techniques to satisfy the student sector which as cited as the most vital entity in the educational sector. New technologies, tools, and techniques are proving as a boom for innovative teaching and learning practices. One of the emerging teaching technique is Blended learning which is a process refers to “mixing of the different learning environment for educational transfer”. It combines the traditional face to face classroom method with online learning method supported by advanced technology and tools. Blended learning should be viewed not only as a temporal construct but also as a fundamental redesign model. Through this content, delivery becomes digital and online. Truly blended learning requires teachers should adopt the approach as guides and mentors and learning should go beyond the classroom walls. Blended learning is also known as Hybrid learning. Although, Indian Government is taking initiatives to implement a blending learning approach yet there is a need to access the behavioral aspect of the students to use this blending learning approach. Adopting a blended learning approach must start with a re-examination of the intended learning outcomes.The deployment of cloud in the blended learning process makes its existence more strong. This study is the review of literature selected to identify the need for blended learning deploy with cloud in the teaching-learning process in the Higher Education Sector.

Inderbir kaur

his study aims to explain the optimization of the ARCS learning model as an effort to increase the learning motivation of students, especially in thematic learning at MI At-Taqwa Bondowoso. The method used is qualitative with a descriptive qualitative approach, while the type of research used in this research is field research. The data collection techniques used interviews, observation, and documentation. Data analysis used was condensation, data presentation, and verification. And the validity of the data uses triangulation of sources and techniques. The results of this study indicate (1) Thematic Learning Problems at MI At-Taqwa Bondowoso, namely: Teachers are less biased in utilizing learning media, so that the only sources used are textbooks, classroom learning is only centered in the teacher, the students' lack of interest in the learning process, so that students do not pay attention to the teacher who teaches. (2) The application of the ARCS model in thematic learning at MI At-Taqwa Bondowoso, namely: The implementation of the ARCS model was carried out by teachers with several methods and strategies such as modeling the way strategy and also contextual teaching and learning, ARCS Model as an alternative solution in learning for increasing students 'learning motivation is able to stimulate students' enthusiasm in thematic learning.

Educare: journal of primary education

Aim: To evaluate the hepatoprotective activity of the chloroform extract of the selected Glinus lotodies linn plant by using Paracetamol induced hepatic injury in albino rats. Methods: The chloroform extract of Glinus lotodies linn was allowed for screening hepatoprotective activity on Paracetamol induced Albino rats and they were compared with standard and negative control. Results: The drug treatment Chloroform Extract of Glinus lotodies linn [CEGL] was carried out at two low dose levels 200mg and 400mg/ kg, both of which along the standard Silymarin 100mg/kg treated group showed a significant reduction in the elevated enzyme levels (P < 0.01). Liver section shows normal cells compared to control. Conclusion: These data suggests a dose dependent hepatoprotective activity of CEGL. At the end of this study, a strong conclusion can be drawn that the Chloroform Extract of Glinus lotoides linn possess hepatoprotective activities induced by Paracetamol in Albino rats.

Sudha rameshwari.k assistant professor

The purpose of this study is to describe the planning, implementation and evaluation of the tahfidzul Al-Qur'an program for students volume 5 at MI Muhammadiyah 02 Pontang Ambulu Jember. This study uses a qualitative approach and the technique of determining data sources using purposive sampling. Collecting data through observation, interviews and documentaries. Data analysis, descriptive qualitative with data reduction steps, data presentation, conclusion drawing/verification. To check the validity of the data using triangulation of sources and techniques. The results of the research show: (1) Planning the tahfidzul Al-Qur'an program for students volume 5 at MI Muhammadiyah 02 Pontang Ambulu Jember, namely: determining the goal of memorizing 2 letters Al-Insyiqaq and Al-Muthoffifin, instilling a love of the Qur'an since early, Content of material, determine method, Determination of media, Determination of evaluation. (2) The implementation of the tahfidzul Al-Qur'an program for students volume 5 at MI Muhammadiyah 02 Pontang Ambulu Jember, namely: students memorizing letters Al-Insyiqaq and Al-Muthoffifin, reading letters according to makhraj and tajwid, Submission of material by teachers, using tilawati method by listening, imitating, reading together and repeatedly, using Juz 'Amma, Al-Qur'an and murottal media. (3) Evaluation of the tahfidzul Al-Qur'an program for students volume 5 at MI Muhammadiyah 02 Pontang Ambulu Jember, namely: evaluation of objectives, evaluation of material based on the target of memorizing letters Al-Insyiqaq and Al-Muthoffifin and not experiencing difficulties, evaluation of methods, formative evaluation at the end of each lesson and letter increase.

Educare: journal of primary education

The present study was designed to investigate the in-vitro thrombolytic activity of various extracts of seeds of Salvia hispanica by Clot lysis method. In this study, Streptokinase was used as a positive control and the human blood was taken as test sample. The mean % of clot lysis for streptokinase was found to be 66.8%. Similarly the methanolic, ethanolic, aqueous and acetonic extracts of salvia hispanica exerted 48.5%, 35.8%, 33.3%, 27.7% lysis of the blood clot in thrombolytic activity test respectively. From our findings it was observed that all the extracts of Salvia hispanica revealed remarkable thrombolytic activity

Zeenath banu

Information and communication technology is an instrument in addressing some of the issues of Indian higher education however; there are certain drawbacks to using ICT to enhance teaching and learning. The present research was carried out in The Maharaja Sayajirao University to study the impediment faced by them in the use of ICT in their professional work. Quantitative data was collected from two hundred and ninety faculty members through the purposive and convenient sampling method. The data indicate that faculty members faced technological infrastructure-related impediments such as lack of smart boards, lack of computers, uneven bandwidth of internet, slow internet connection. It is suggested that an adequate atmosphere be developed in the institution that would encourage faculty members to use ICT.

Maniar avani

Tuberculosis is communicable disease which is common and often deadly infectious disease caused by mycobacterium tuberculosis. Tuberculosis continues to be a major public health problem in the world. The aim of this study is to assess prevalence and associated risk factors of pulmonary tuberculosis. Treatment and development of multidrug-resistant tuberculosis were also considered. Drugs for Pulmonary tuberculosis confirmed cases used in calculating tuberculosis prevalence in Libya which is obtained from archive department of Abu Seta Hospital. Data obtained from 427 files during 2019 determine the incidence and epidemiology of tuberculosis in Libya. For a total of 427 confirmed cases of pulmonary tuberculosis, about 75.0% of the cases were male and most of the patients (55.0%) were within the age group of 20 - 40 years old. Of the study patients, 114 patients (26.7%) were viral infected and most of the viral infected cases were in the age group of 20 - 40 years and the majority of this age group patients (n = 41, 53.2%) were infected with HIV/HCV, while the least percentage in this group age were infected with HIV/HBsAg (01.3%). Among 427 cases, 73 cases (17.1%) were comorbid with other chronic diseases. Of the 73 cases, 54 cases (74.0%) were diabetes mellitus whereas only 1.4% of them had bronchial asthma, Parkinsonism and renal failure. The drug therapy of active tuberculosis disease needs combination chemotherapy to escape the selection of naturally occurring drug-resistant mutants. Amongst current anti tuberculosis drugs, the rifamycins hold the highest potential for shortening treatment and improving effects. Prevalence of smear positive tuberculosis and bacteriologically confirmed that a high rate of tuberculosis among unemployed population. This study reported that the highest incidence rate is found in people who are smokers.

Mediterranean journal of pharmacy and pharmaceutical sciences

The rate of oxygen consumption was measured in mercury chloride treated freshwater fish, cyprinus carpio for 96h and compared to control group. The present investigation showed that average oxygen rate was decreased in all treated animal as compared to controlled group. Behavioural changes was also recorded in both concentration. The behavioural alterations observed like surfacing, erratic movement, increased mucous secretion, decreased opercular movement and loss of balance. The present study revealed that, mortality rate increased with increases in concentration.

.vijay digambar suryawanshi

Higher Education has an important role in the task of rebuilding a nation and it paves the way for overall development of a nation. The twentieth century has witnessed several revolutions like Green revolution, White revolution, I.T revolution etc; transforming human civilization in to new heights. At the start of 21st century, there is a lot of importance given to higher education. Every country realizes the value of higher education and the benefits accrue from it. There is a greater importance attached to higher education. “The social demands for higher education continue to increase. Indian higher education has a rich and complex history that spans millennia. This abstract provides an overview of the key developments in Indian higher education, highlighting its evolution from ancient times to the modern era. The history of Indian higher education is marked by the establishment of ancient centers of learning, the influence of various empires and dynasties, colonialism, and post-independence reforms. This abstract also touches upon the challenges and opportunities that have shaped the landscape of higher education in India.The history of Indian higher education can be divided into several distinct periods. In ancient India, centers of learning such as Takshashila and Nalanda emerged as renowned seats of knowledge, attracting students and scholars from across the world. These institutions laid the foundation for a tradition of rigorous intellectual inquiry

Dr gedam kamalakar