Background: Gestational hypertension (GHTN) is defined as a new rise in blood pressure (BP) ≥140/90 mm Hg, presenting at 20 weeks gestation without significant proteinuria. Worldwide, 4.4%-15% of all pregnancies are complicated by HTN. The aim of this study was to determine the incidence of GHTN among pregnant women in Enugu State, Southeast Nigeria with a view to improving and strengthening antenatal services in the State to help reduce the proportion of maternal mortality and fetal outcomes attributable to GHTN and reduce the overall prevalence of HTN in the country. Methods: Records of BP, biodata and laboratory investigations (urinalysis, full blood count) of women who attended antenatal clinics in six selected state hospitals (2006-2015) were examined. Data were analyzed as proportions, t-test, ANOVA and Pearson product moment correlations using Maxstat (version 3.60) statistical software. Results: The overall incidence of GHTN was 5.9% with annual fluctuations with peaks in 2010 and 2014. There were significant differences in incidence among the age groups (<20>35 years) (p<0 p=0.0016).>35 years) and GHTN (r=0.932, p=0.0069). Between parity and GHTN, there was also positive, strong and significant correlation (r=0.813, p=0.0491). Conclusions: With an incidence of GHTN at 5.9%, there is need to improve and sustain adequate antenatal services in order to help reduce the proportion of the country’s maternal mortality attributable to hypertensive disorders of pregnancy.

Emmanuel umegbolu

Background In 2016, the Tanzanian government shifted the vaccine supply chain responsibilities from the Medical Store Department (MSD) to the Expanded Program on Immunization (EPI) to reduce costs. However, cost estimates that informed the decision were based on invoice value of vaccines and related supplies, rather than a proper economic evaluation study. Therefore, this study aims to compare the actual storage and distribution costs of vaccines and related supplies between MSD to EPI. Method Micro-costing approach was used to estimate resource use at MSD and EPI for the year 2018. Data were collected through a review of documents, warehouse databases, and interviews with key staff at MSD and EPI. We included both capital and recurrent costs. Microsoft Excel® was used for analysis with input data from the UNICEF forecasting tool, WHOs vaccine volume and capacity estimation tool, diesel generator calculator, and supply chain service fee estimator version 1.02. Results The total vaccine storage and distribution costs were estimated to be USD 1,996,286 at MSD and USD 543,648 at EPI. Distribution and program management costs represented 41% (USD 819,288) and 38% (USD 762,968) of the total costs at MSD, while storage and distribution costs represented 43% (USD 234,423) and 34% (USD 184,620) of the total costs at EPI, respectively. The cost drivers at MSD were fuel and transport (21%), receiving and dispatch (19%) and, program management personnel cost (14%), while at EPI were storage space (20%), program management personnel cost (18%) and fuel and transport (15%). Conclusion The storage and distribution of vaccines in Tanzania via the EPI reduced the vaccine supply chain cost to about 27% of the program costs at MSD.

Dr. omary swallehe

Field studies were carried out in wet seasons of 2014 and 2015 in rice fields of College Farm, Rajendranagar, Hyderabad to understand the abundance and biodiversity of spiders in varied rice cultivation systems. Design of the experiment was split plot with three main modules, viz., transplanted, broadcasted and drum sown rice and subtreatments under each main module included three plant protection methods viz., organic protection, farmers’ practices and ‘no protection’ practices. Results showed that predator numbers in ‘no protection’ and organic protection plots of all main treatments were more than in farmers’ practices indicating the impact of the chemical pesticides. A total of 22 genera of spiders belonging to 12 families were recorded which comprised of seven guilds based on their hunting strategies and microhabitats. Shannon diversity index ranged between 1.83 and 2.26 and Pielou’s evenness index was 0.59-0.72 in two years of study indicating a stable ecosystem and even species distribution in rice crop at Rajendranagar. Study of the guild assemblage indicated that orb-weavers constituted 28.1% of the population, ground runners 23.51%, space web builders 18.38%, sheet-web builders 13.12%, stalkers 8.04% and ambushers made upto 0.38% of the spider population. Understanding the vertical stratification of various spider genera on the plant gave further insight into the prey preferences of these predators.

Gorthi anitha

Assessment of convergent validity of latent variables is one of the steps in conducting structural equation modeling via partial least squares (PLS-SEM). In this paper, we illustrate such an assessment using a loadings-driven approach. The analysis employs WarpPLS, a leading PLSSEM software tool.

Johnny amora

Cleome scaposa DC. has long been used in traditional herbal medicine for the treatment of pain and inflammation. The present investigation is an attempt to evaluate the antiemetic, analgesic and anti-inflammatory activities of Cleome scaposa leaves methanolic extract by using the chick emesis model (oral treatment), analgesia meter test (intraperitoneal treatment) in rats and carrageenan-induced rat paw oedema (oral treatment) respectively. The antiemetic activity (150 mg/kg b.w. of extract) was carried out by using chlorpromazine (150mg/kg) as a standard antiemetic drug. The analgesic activity (250 mg/kg b.w., of extract) was performed by using diclofenac sodium (50mg/kg) as a standard analgesic drug whereas, anti-inflammatory activity (500mg/kg b.w., of extract) was done and indomethacin (10mg/kg) was taken as a standard anti-inflammatory drug. The results showed significant antiemetic, analgesic and anti-inflammatory effects.

Dr. salman ahmed

The current study seeks to develop and validate a high-performance liquid chromatography method for atorvastatin diastereomer separation and analysis. In particular, we wish to identify the many diastereomers in atorvastatin, which can help us to better understand their pharmacological properties and provide significant information for pharmaceutical applications. Atorvastatin was chromatographed on a Chiralcel® OD-RH column and n-hexan-2-propanol (95:05 v/v) as the mobile phase, with an injection volume of 10 µL. The solution was pumped at a continuous flow rate of 1 mL/min, with a detection wavelength of 260 nm. The investigation found two peaks with retention times of 3.23 and 3.85 min, respectively. The resolution, capacity, and selectivity factors obtained were Rs = 1.2, k′1 = 3.50, k′2 = 4.37, and α = 1.24.

Mediterranean journal of pharmacy and pharmaceutical sciences

Purpose of this study is examining the cause of stress among selected private banking employees. Stratified sampling method was used to carry out the data collection. For this employee of various private banks were chosen. A questionnaire with 12 items with dichotomous (Yes-1, NO-2) were developed and tested for reliability and prior to the distribution of questionnaire. 253 respondents were selected from various private banks in Mysore district, Karnataka state India. The survey questionnaire was sent via email, requesting to complete it. The questionnaire includes 11 demographic information’s and statements to measure. Chi-Square analysis was carried out to examine the cause of stress among employee using SPSS21. We found that designations have significant influence on employee and The other factors of do not have any significant influence on employee. Therefore we concluded that in private banks demographic variable such as designation creates stress in all aspects. Future research should consider a larger sample from leading sectors where job natures are similar. Analysis should be more rigorous, where Amos could be used for analysis.

Dr manjunatha m k

Background: Unexplained infertility is a frustrating diagnosis both for the patient and the clinician, with a prevalence of 16%-37%. It commonly refers to a ‘diagnosis’ made when tubal, ovulatory and husband factors are ruled out. A couple is usually referred for evaluation after 1 year of unsuccessful trials of conception with unprotected intercourse in the fertile phase of the menstrual cycle. Unani formulation comprises of baikh asgand (Withania somnifera Dunal), baikh piyabansa (Barleria prionitis Linn), gule dhawa (Anogeissus latifolia) and gule nilofar (Nymphaea alba Linn) were used for the treatment of uqr, possessing the properties of muqawwi rahim, moaene hamal, moallide mani, etc. Case presentation: A married couple (22 years female partner & 26 years male partner) presented to NIUM Hospital OPD, with chief complaint of failure to conceive since 5 years. The couple report a high degree of stress related to their lack of success. Investigations were carried to check for tubal patency, ovulatory function and semen analysis. Diagnosis of unexplained infertility was made after thorough evaluation of the case. The powder of above mentioned formulation was given 6g twice a day orally with milk from 5th day of cycle for 5 days. Patient got conceived after taking treatment for two consecutive cycles. Discussion: Here we report evidence based management with Unani medicine to help combat the significant physical, psychosocial and economic toll on couples. Keywords: Unexplained infertility; Primary infertility; Uqr; Muqawwi rahim; Moaene hamal; Moallide mani; Unani medicin

Dr ismath shameem

Around the world, several oral health measures have been implemented. The most popular method is to use a toothpaste. However, chewing sticks are still used in many cultures around the world in a conventional manner. Chewing sticks have a mechanical cleansing action similar to a toothbrush in addition to their antimicrobial effect. The purpose of this study is to evaluate the effect of Miswak on the growth of Candida species and to compare it to that of toothpaste. A cross-sectional study was carried out on 120 selected randomly volunteers from January to April, 2022. Two groups of participants were used for two weeks. The participants were separated into a group used Miswak and a group use ordinary toothpaste. Samples were collected before and after two weeks in these two groups. Samples were immediately processed for microbiological phenotypic conventional methods and in vitro susceptibility testing of the microbial isolates to antimicrobial. The findings show that a significant effect of Miswak against an oral cavity candida species. Total candida count was 27.5 ± 18.48, P = 0.001 (Mean ± SD) from Miswak group and 247.0 ± 90.14, P = 0.979 (Mean ± SD) in toothpaste group. The most frequent Candida isolates organisms were C. albicans: 22 (36.67%) in the Miswak group and 24 (40.0%) in the toothpaste group, the second isolate was C. dubliniensis: 04 (6.69%) in the Miswak group and 12 (20.0%) in toothpaste group followed by C. glabrata: 02 (3.33%) in Miswak group. In conclusion, Miswak has a considerable antifungal impact immediately and after two weeks of use.

Mediterranean journal of pharmacy and pharmaceutical sciences

E-learning is the latest buzz word since the spread of Information Technology (IT). In a Country like India, a lot of jobs are being generated through IT. E-learning has contributed to this learning curve of the candidates. The students are still more familiar with the traditional mode of teaching which offline mode. Some have accepted both. The reach of online mode of learning needs to be assessed. This paper tries to find the learning preference of students in Kerala. Also certain factors that contribute to the preference of online learning has also been identified. Covid-19 has impacted the education sector in a big way. As we look into the future, the relevance of online learning has increased but the offline mode which was the traditional mode of learning and teaching, has not lost its place among this Information Technology era

Dr.ranjith somasundaran chakkambath

Background: Parkinson’s disease (PD) is one of the most common, disabling neuro-degenerative disorders. The disease has a significant clinical impact on patients, families, and caregivers through its progressive degenerative effects on mobility and muscle control. Available treatments for PD have varied results. Although there are anecdotal reports of improvement with Homoeopathy, there is a dearth of literature concerning usefulness in management of PD Objectives: To assess the usefulness of ultrahigh dilution of Zinc in the management of PD. Methods: A case of PD under standard care and refractory to treatment visited Out- Patient Department and was assessed with and Unified Parkinson’s Disease Rating Scale (UPDRS). As per the classical Homoeopathic guidelines Zincum metallicum 200 was prescribed after Repertorization. Results: UPDRS total score of 112 at baseline turned to 40 at the end of 1 year and 7 at the end of two years, in spite of reduction in the conventional medicines. Patient was on Stage 3 of Modified Hoehn and Yahr staging at the baseline and turned to Stage O in duration of 21 months. SEADL score has turned from 40% to 100%. Conclusion: Homoeopathic medicine Zincum met. is a valuable adjuvant in the management of Parkinson’s disease.

Dr deepthi gilla

This study aims to improve the ability to think critically in class IV SDN 1 Sukamulya in science subjects through the application of learning strategies jeopardy review. This type of research is a quantitative study using the method research Quasy Experimental Design and the design used is pretest-poststest design. The population in this study were students of class IV (A, B, dan C) SDN 1 Sukamulya Academic year 2019/2020. Totaling 85 students, while the samples in this study were group IVB as the experimental class and class IVC as the control class. The sample was taken using cluster random sampling technique. In this study, the data collection tools used were test, observation, and dokumentation. The instrumen test used was critical thinking essay questions. Hypothesis testing using statistical analysis Independent Sample t-Test. Based on the result of the study obtained the average value of the experimental class 83,00 while the average value of the control class was 76,28. Results hypothesis testing using the analysis of Independent Sample t-Test with a significance level 5% (0,05), i,e. 0,000 < 0,05 so that H0 is rijected and Ha is accepted, so it can be drawn conclusion that there is an influence of the jeopardy review learning strategy on critical thinking skills of grade IV students on material wealth of energy sources in Indonesia at SDN 1 Sukamulya Academic Year 2019/2020. Penelitian ini bertujuan untuk meningkatkan kemampuan berpikir kritis kelas IV SDN 1 Sukamulya pada materi IPA dalam tema kayanya negeriku dengan cara menggunakan strategi pembelajaran jeopardy review pada saat proses pembelajjaran berlangsung. Jenis penelitian yang digunakan oleh peneliti adalah penelitian kuantitatif dengan menggunakan metode penelitian Quasy Eksperimental Group Design dan menggunakan desain penelitian yakni Pretest-Posttest Group Design. Populasi pada penelitian ini adalah peserta didik kelas IV (A, B, dan C) SDN 1 Sukamulya Tahun Pelajaran 2019/2020 yang prserta didiknya secara keseluruhan berjumlah 85 peserta didik, sampel pada penelitian ini yakni kela IV B sebagai kelas penelitian dan kelas IV C berperan sebagai kelas kontrol. Sampel ini diambil dengan menggunakan cara cluster random sampling. Pada penelitian ini instrumen yang digunakan yaitu observasi, dan test, serta dokumentasi. Instrument test yang digunakan yakni soal dalam bentuk essay untuk mengukur kemampuan berpikir kritis. Uji hipotesis pada penelitian ini menggunakan analisis data statistik Independent Sample t-Test. Berdasarkan hasil penelitian diperoleh hasil nilai rata-rata kelas eksperimen sebesar 83,00 sedangkan nilai rata-rata kelas kontrol sebesar 76,28. Hasil uji hipotesis menggunakan analisis Independent Sample t-Test dengan menggunakan taraf signifikasi 0,05 (5%), yaitu 0,000 < 0,05 sehingga hasilnya H0 ditolak dan H1 diterima, sehingga dapat disimpulkan bahwa terdapat pengaruh strategi pembelajaran jeopardy review terhadap kemampuan berpikir kritis peserta didik kelas IVB pada materi IPA tema kayanya negeriku di SDN 1 Sukamulya Tahun Pelajaran 2019/2020.

Educare: journal of primary education

The Cellular Manufacturing is adopted in batch type manufacturing industries nowadays for their production with increased productivity, less cost and time with effective control. The proposed optimization model is used to determine the cost of machine cells, i.e., machine duplication, part subcontract, inter intra cellular movements cost and cost of production associated with machine cell, such as machine reconfiguration and part inventory considering machine flexibility for various time periods. Initially, mathematical model is proposed to calculate machine cell cost with and without considering machine flexibility and then another lpp integer model is proposed to calculate the machine cell production and associated cost for the changes in time period, part type and volume considering machine flexibility. The manufacturing data in the incidence matrix and machine cell, part family data in the block diagonal form are given as input to the optimization programming language Cplex and the output are given for the two mathematical models. The data related to machine duplication, part subcontract, inter intra cellular movement; machine reconfiguration and part inventory are given. Two dimensional shop floor layouts are presented in rectilinear coordinates for all the problems for easy analysis of material movement length and shop floor area

S ramesh

The purpose of the study was to find out the effect of pranayama on type-2 diabetes on metropolitan people. In the present study researcher wants to observe the effect of pranayama on type 2 diabetes on metropolitan people and to develop a specific package for type 2 diabetes. For this purpose researcher collect 60 sample from nearest diabetic Clinic and Hospital in the city and it is randomly divided into two groups one is experimental and another is control group. In the study researcher used bio-chemistry lab tools. In the study research design used Pre-test, post-test control-experimental group and researcher used two variable type 2 diabetes as dependent and pranayama used as independent variable and in the study there was significant effect of yogic practices on type 2 diabetes.

Shekhar boro

The adulteration and substitution of crude drugs is a burning problem. No doubt, substitution is helpful in places where the unavailability of particular oil drugs and or unwanted adverse effects of the desired crude drugs are there and have a choice of another drug with similar pharmacological effects and less unwanted aftereffects. However, in most cases, it is unacceptable because the conversion of authentic drugs into substandard medications may cause a variety of adverse effects, from mild and moderate to severe life-threatening reactions. So, understanding all the ways of adulteration and substitution is necessary to rectify this illegal act and maximize consumers' safety. At the end of this review, the Botanical Adulterant Program of the American Botanical Council is also highlighted.

Dr. salman ahmed

This paper examines the influence of empowerment on job satisfaction in five-star hotels in Jordan. The influence of empowerment on job satisfaction remains a relatively unexplored area. A 52-item questionnaire, measuring empowerment and job satisfaction, was distributed to 332 employees in 12 five-star hotels in Jordan with a 56% response rate. Principal components analysis determined the factor structure and regression analysis determined the influence of empowerment on job satisfaction. The results revealed both structural and psychological empowerment have significant individual influences on job satisfaction, but more significant when structural and psychological empowerment are combined. Most of previous studies were conducted in western economies and little in the Middle East generally and Jordan in particular. This research contributes to the literature by including both dimensions of empowerment where previous scholars used only one.

Mukhles m. al-ababneh

The present review shares updated data on the botany, distribution, traditional medicinal uses, phytochemistry and pharmacology of Macrotyloma uniflorum (Lam.) Verdc. All provided information was obtained through Google Scholar, Pubmed, SciFinder, Scirus, Web of Science and a library search.

Dr. salman ahmed

“Phyllanthus emblica” known to be amla has role in the skin aging influences the changes in skin, including skin dryness, wrinkle, and irregular pigmentation. Initially the 6 day observation has been taken for the ageing activity to be track to study the TREM2 pathway of “Phyllanthus emblica”. Cellular observation and pathway consideration: The environmental impact of pH, Temperature, Humidity and stability of amla fruits is important for the ageing of cells in neuronal cascade of TREM2 Pathway, while studying the fruits cell cycle. The melanin suppression through inhibition of tyrosinase and tyrosinase-related protein-2 activities, the strong antioxidant, and the potent matrix metalloproteinase-2 in cellular observation of tyrosinase pathway. The study aimed to evaluate the anti-skin aging efficacy of amla.

Wahul umesh

The purpose of this research was to investigate the relationship between affective tendencies in embarrassing situations and cheating behavior in a sample of adolescents. Two objectives were addressed: first, exploring the relationship between cheating behavior and shame-proneness, guilt-proneness, externalization, and detachment; second, analyzing the mediating role of detachment in the relationship between externalization and cheating behavior. The results showed positive correlations between the cheating behavior and externalization and detachment, a negative correlation with guilt, and no relation with shame. It was confirmed the mediating role of detachment. Implications for educators were discussed, emphasizing the importance of stimulation of students’ moral rules understanding.

Elena stănculescu

Nine fruit morphological traits were studied in ten stands of Jatropha curcas spread in eight forest divisions of Uttarakhand. Variation was examined at stand level as well as at tree level. Significant differences were found among stands for fruit length, fruit diameter, pericarp weight per fruit, seed: fruit weight ratio, kernel: fruit weight ratio and pericarp: fruit weight ratio traits while all morphological traits showed significant differences among trees within stands. The estimation of the variance components, however, revealed that the fruit traits, especially weight traits viz. fruit weight, total seed weight per fruit and total kernel weight per fruit have negligible contribution from stands and small contribution from trees. Maximum variation was found among fruits within trees (i.e. at fruit level or error). Pericarp weight per fruit and fruit ratio traits (i.e. seed: fruit weight ratio, kernel: fruit weight ratio and pericarp: fruit weight ratio) were affected to small extent by stand per se. The repeatability of all fruit traits at tree level were also low to moderate (0.105 to 0.278)

Kshitij malhotra