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Anti-emetic activity of some leguminous plants

  • Authors Details :  
  • Muhammad Mohtasheemul Hasan,  
  • Iqbal Azhar,  
  • S. Muzammil,  
  • Salman Ahmed,  
  • Syed Waseemuddin Ahmed

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Crude methanol extracts of the leaves of Adenanthera pavonina L., Peltoforum roxburghii L, Prosopis cineraria L., and Prosopis juliflora DC., were evaluated for anti-emetic activity. Emesis was induced by the oral administration of copper sulphate 50mg/kg body weight to male chicks of four days age. The anti-emetic activity was determined by calculating the mean decrease in number of retching in contrast with those of control. All extracts (150 mg / kg body weight orally) showed anti-emetic activity when compared with standard drug Chlorpromazine at the same dose. Among all the extracts, Prosopis juliflora showed the highest (73.64%) and Adenanthera pavonina showed the lowest (50.17%) anti-emetic activity

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