Sudha Rameshwari.k Assistant Professor
Hepatoprotective activity of glinus lotodies linn against paracetamol induced liver damage in albino rats
Journal title : International journal of health sciences
Publisher : Universidad Tecnica de Manabi
Print ISSN : 2550-6978
Page Number : 4911-4918
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Aim: To evaluate the hepatoprotective activity of the chloroform extract of the selected Glinus lotodies linn plant by using Paracetamol induced hepatic injury in albino rats. Methods: The chloroform extract of Glinus lotodies linn was allowed for screening hepatoprotective activity on Paracetamol induced Albino rats and they were compared with standard and negative control. Results: The drug treatment Chloroform Extract of Glinus lotodies linn [CEGL] was carried out at two low dose levels 200mg and 400mg/ kg, both of which along the standard Silymarin 100mg/kg treated group showed a significant reduction in the elevated enzyme levels (P < 0.01). Liver section shows normal cells compared to control. Conclusion: These data suggests a dose dependent hepatoprotective activity of CEGL. At the end of this study, a strong conclusion can be drawn that the Chloroform Extract of Glinus lotoides linn possess hepatoprotective activities induced by Paracetamol in Albino rats.
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DOI : https://doi.org/10.53730/ijhs.v6nS4.9195
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