Concrete is a material which is used in construction. Weight of concrete plays a major role in the construction industry. If the weight of the concrete is increased, it will pose more structural problems on the later date of construction. It also increases the cost of construction, without any specific benefit. So if lightweight concrete is used, it not only reduces cost of construction, but also not poses any structural problems unnecessarily. Light weight concrete also aids workers in smooth handling of materials. In this study, vermiculite in the form of exfoliated form is used to replace partially natural sand. By this action dead weight of the structure is reduced. Once the dead weight of structure is reduced, it in turn reduces cost of construction. In this study three mixes were casted with the cement content of 383 kg/m3 in M20 concrete and the water cement ratio of 0.45 is chosen. Vermiculite at 10%, 20% and 30% are choosing to partially replace the natural sand. The Tests conducted on concrete for evaluating mechanical properties include compressive strength and split tensile strength. For evaluating durability properties, tests like acid resistance, sulphate resistance, chlorine penetration and water absorption.
Purpose: To assess incidence of demodex species, correlate ocular symptomatology, evaluate efficacy of coconut oil as treatment method in all types of blepharitis. Materials and Methods: 30 patients with anterior & mixed blepharitis, meibomian gland dysfunction & non-specific irritation were enrolled for study. History taken & examined clinically. 2 lashes/lid were sampled & mounted on slides with normal saline & observed under light microscope. Number of mites counted. Patients positive for demodex were treated with coconut oil application over lid margins & reviewed after 3 weeks. Results: Incidence of demodex was 40% & it increased with age. Demodex was commonly associated with meibomian gland dysfunction, non-specific irritation, madarosis, cloudy & toothpaste like meibum quality. Burning sensation and itching were common complaints. At 3rd week, all patients were symptom-free. Mite count dropped by 52.8% but were not eliminated. Conclusion: Demodex infestation is often overlooked but it is associated with about half of blepharitis cases. Hence further evaluation should be considered. Coconut oil is an easily available mode of treatment & helps reduce symptoms and mite counts.
Character education is an effort to foster and shape student character according to school culture. The research objective was to describe the process of cultivating character in students through school intracurricular and extracurricular activities. The research method with qualitative, data collection with interview, observation, and documentation. The results showed (1) character planting through intracurricular activities with (a) strengthening learning, namely character building in accordance with the theme or material, and (b) spiritual paradigm by inserting Islamic values ??in the learning process. (2) character planting through extracurricular activities with (a) scouts, namely forming leadership characters, being independent, solving problems, and loving nature, (b) leadership, forming leadership characters, responsibility, and making decisions, (c) painting, forming detailed, focused, creative characters , (d) martial art, forming tough, skilled characters, (e) reciting recitation, forming religious, moral, orderly characters, (f) child preachers, forming brave characters, positive thinking, art of communication, influencing others. Pendidikan karakter merupakan upaya membina dan membentuk karakter siswa sesuai dengan budaya sekolah. Tujuan penelitian untuk mendeskripsikan proses penanaman karakter siswa melalui kegiatan intrakurikuler dan ekstrakurikuler di sekolah. Metode penelitian dengan kualitatif, teknik pengumpulan data dengan wawancara, observasi, dan dokumentasi. Hasil penelitian ini menunjukkan: (1) Penanaman karakter melalui kegiatan intrakurikuler dengan cara (a) Penguatan pembelajaran yaitu pembentukan karakter yang sesuai dengan tema atau materi, dan (b) paradigma spriritual dengan menyisipkan nilai keislaman dalam proses pembelajaran. (2) Penanaman karakter melalui kegiatan ekstrakurikuler, (a) Pramuka yaitu membentuk karakter kepemimpinan, mandiri, memecahkan masalah, dan cinta alam, (b) Kepemimpinan, membentuk karakter kepemimpinan, tanggung jawab, dan membuat keputusan, (c) Melukis, membentuk karakter detail, fokus, kreatif, (d) Pencak silat, membentuk karakter tangguh, terampil, (e) Mengaji, membentuk karakter religious, akhlak, tertib, (f) Pendakwah cilik, membentuk karakter berani, berfikir positif, seni komunikasi, mempengaruhi orang lain.
The rate of aging is rapidly increasing and the term of geriatric refers to offer a medical care to elderly people. Drug consumption study on geriatric population is a vital issue since this group is totally neglected in Libya. The aim of this study was to assess drug utilization pattern among elderly patients in terms of world health organization core prescribing indicators and to evaluate the treatment cost. A total of 106 prescriptions were randomly collected from different community pharmacies located in Tripoli during the summer 2019, and were evaluated (total number of prescribed drugs is 359) for their clinical efficacy and safety. The findings revealed that 60 drugs acting on GIT (16.7%), 50 antimicrobial drugs (13.9%), 31 antihypertensive drugs (8.6%) and 30 drugs for respiratory diseases (8.4%) were prescribed to patients who are 65 years old or more. With regard to disease pattern in the elderly Libyan patients, 27 drugs were prescribed for diabetes mellitus (7.5%), 24 drugs for cardiovascular drugs (6.7%) and 14 drugs for anti-hyperlipidemia (3.9%). According to the WHO core drug use indicator pattern, the average number of drugs prescribed per encounter was 3.3. Prescription by generic name was low (41.5%). Antibiotics were 36.8% while injections were 26.6%. Thus, this study suggest that geriatric medicine and rational drug use should strongly be implanted in medical schools and teaching hospitals. Besides, a drug pattern use of the Libyan community is urgently required to avoid drug prescribing errors.
PHYSICO-CHEMICAL ANALYSIS OF RHIZOSPHERIC SOIL OF MAIZE (Zea mays L.) AND ITS EFFECTS ON MAIZE DISEASE INCIDENCE (IN VIVO) IN KARNATAKA
Kegiatan keagamaan merupakan kegiatan yang amat penting di MI Negeri 3 Jember, mengingat masih banyak peserta didik yang membutuhkan bimbingan guru untuk memiliki karakter yang sesuai dengan tuntunan Islam, di zaman teknologi initidak bisa dipungkiri bahwa anak-anak zaman sekarang sudah mengenal yang namanya internet. Maka dari itu pendampingan orang tua dan guru sangat dibutuhkan dalam perkembangan anak-anaknya. Salah satu pendidikan yang diajarkan guru kepada peserta didiknya sejak dini adalah pengajaran tentang al-Qur’an.Oleh karena itu darus keliling (darling) merupakan kegiatan yang tepat dalam proses membelajarkan al-Qur’an dalam rangka menanamkan karakter religius kepada peserta didik. Fokus penelitian yang dikaji adalah: Bagaimana peran guru sebagai pembimbing dalam menanamkan karakter religius peserta didik melalui kegitan ekstrakurikuler darus keliling (darling) di MI Negeri 3 Jember tahun 2019? Penelitian ini memperoleh kesimpulan: Peran guru sebagai pembimbing dalam menanamkan karakter religius peserta didik melalui kegiatan ekstrakurikuler darus keliling di MI Negeri 3 Jember dalam hal ini adalah guru yang senantiasa membimbing anak-anak anggota darling untuk belajar al-Qur’an. Darling ini adalah sebuah wadah yang diberikan oleh guru untuk mengembangkan potensi peserta didik. Karakter religius pun terbentuk yakni sikap patuh dalam menjalankan agama Islam, misalnya membaca al-Qur’an. keliling di MI Negeri 3 Jember dalam hal ini menggunakan instrumen penilaian yang memiliki 3 aspekpenilaian yakni aktif, kurang aktif dan tidak aktif.
The study was conducted by researcher on Coping strategies adopted among adolescents in selected Schools, Distt. Mohali, Punjab. The main aim of this study was to assess on Coping strategies adopted among adolescents, to find out the association between coping strategies adopted among adolescents with their selected socio demographic variables.Descriptive Research design has been used to assess the Coping strategies among 400 adolescents studying in Golden Bell’s school,Sector-77 and Shemrock School, sector 69, in Distt Mohali,Punjab. The sample was selected by Systematic random sampling technique. Pilot study was conducted on 10% of population and sample consists of 40 adolescents. Data on Coping Strategies adopted among adolescents were collected under two sections, Section A- Socio demographic variables and Section B- Coping Strategies Scale of Prof. A.K. Srivastava to assess coping strategies adopted among adolescents. Data was analyzed through Descriptive and inferential statistical methods. The results showed that majority of adolescents were adopting moderate Coping Strategies.There was significant association between Coping Strategies adopted by adolescents with their selected demographic variable such as Class of study, Occupational Status of Mother and Monthly Family Income.Based on the findings of the study, recommendations were drawn on nursing service, nursing education, nursing administration and nursing research.
Vitamin C causes a significant change in pharmacological effects of some drugs which may lead to unpredictable responses. Vitamin C-haloperidol interaction has not been confirmed in vivo. This study was aimed to investigate the influence of vitamin C on some pharmacological effects of haloperidol (extrapyramidal side effects caused by the antipsychotic haloperidol). Albino male mice (n = 24, body weight of 20 - 40 gm) were divided into four groups and each of consists of six mice. Group I (control): given 1% Tween 80 solution, group II: given vitamin C in a dose of 100 mg/kg, group III: given haloperidol (2 mg/kg), while group IV: given a combination of vitamin C and haloperidol. All the treatments were given by intraperitoneal route of administration. Three sub-acute doses of different treatments were given at 24:0, 5:0, 1:0 hour before scoring. Parameters scored were catalepsy, ptosis, rigidity and akinesia. The experiment was repeated using vitamin C in a dose of 500 mg/kg. Both doses of 100 and 500 mg/kg of vitamin C significantly antagonized the effect of haloperidol by decreasing all the tested parameters. The results indicate that vitamin C decreases extrapyramidal side effects caused by the antipsychotic haloperidol and show that it successfully decreases catalepsy, ptosis, rigidity and akinesia in mice.
Service quality in the hospitality industry becomes one of the most important factors for gaining a sustainable competitive advantage and customers’ confidence in the highly competitive marketplace, and therefore service quality can give the hospitality industry a great chance to create competitive differentiation for organisations. It is thus considered as a significant core concept and a critical success factor in the hospitality industry. A successful hotel delivers excellent quality service to customers, and service quality is considered the life of hotel. Many benefits can be achieved by service quality such as establishing customer satisfaction, contributing to business image, establishing customer loyalty, and providing a competitive advantage to a business. Service quality performance can mean different to different people, for example, employees may show higher perceptions of service quality than customers perceived, and thus managers and their employees never like to identify deficiencies in service quality
Abstract Background: Hansen’s disease is a chronic infectious disease with a wide range of clinical manifestations. The clinical diagnosis must be confirmed by histopathological and bacteriological studies in order to adequately manage the condition and prevent drug resistance. Aim: To perform a clinico-histopathological correlation of skin lesions in all patients with a clinical suspicion of Hansen’s disease. Materials and methods: A retrospective, hospital based, cross-sectional study was conducted in the Department of Pathology, Father Muller Medical College, Mangalore. Skin biopsies of all suspected cases of Hansen’s disease received over a period of three and a half years were included in the study. Haematoxylin and eosin, Fite-Faraco stained sections of all cases were reviewed. The cases were classified according to Ridley–Jopling classification into TT, BT, BB, I, BL, and LL. Clinical details of the patient, including type and site of lesion were obtained from the patient’s medical records. Clinico-histopathological correlation was done for all the cases. In addition, wherever available, the corresponding slit-skin smears were also included. Results: A total of 76 cases were clinically diagnosed as Hansen’s disease. Clinico- histopathological correlation was seen in 33/76 cases (43.42%). The most common histological subtype of Hansen’s was Borderline Tuberculoid (BT) - 24/76 cases (31.58%). Maximum agreement was seen in Mid-borderline leprosy (92.11%). Fite Faraco stain was positive in 21 out of 76 cases. Slit skin smears were available for 55 cases and positive in 20 cases. Conclusion: Due to clinical and morphological overlap, it is imperative to correlate the clinical, histopathological and bacteriological index results in order to accurately subtype the categories in Hansen’s disease.
The Sigma Delta Analog to Digital Converter (SD-ADC) with passive analog components is presented. The digital blocks required for creating the samples with required sample rate and word length from the 1 bit ADC output are presented. The digital filters are initially modeled in MATLAB Simulink and validated in frequency domain. Further they are synthesized to Xilinx Spartan-6 FPGA technology. The synthesis results report clock speeds up to 300MHz. The simulation results are used to validate the principle and verify the performance of SD-ADC. The results demonstrate a promising technology area of realizing SD-ADC as a reconfigurable block on FPGA to meet several signal processing applications with sampling rates up to few hundreds of KHz
The recent boom in Android mobile device usage has caused a shift in the information technology and has affected the way how information and data are stored, shared among the mobile users. The advent of social networking applications also demands the availability of resources that can be shared among the authentic users. This paper reviews and compares the available techniques and solutions for detecting Unexpected Permission Authorization to Mobile Apps. It is observed that malware for the android system is also growing significantly, current solutions for detecting malware on smartphones are still ineffective.
The main objective of this study is to examine the relationship between globalization, resource conflicts and peace –building in Africa, with particular emphasis on Nigerian’s north-central geo-political zone. The wave of globalization that has swept across the world with its attendant socio-economic and political consequences lies at the heart of this study. The debate that is raging currently amongst intelligentsias, public analysts, and the international community point to the fact that the global system has suffered increasing setbacks occasioned by the impacts of globalization and contestation for scarce natural resource endowments. The changes that have emerged for several decades in both developed and developing nations, with the latter having a greater share of repercussions, have remained largely daunting. The multiplier effects of these changes have resulted in worsening crisis situations, with a fast growth rate of intra-state and/or trans-regionalized networked conflicts, which is why Africa and indeed Nigeria, has become a hotbed for contestations recently. This work adopts a qualitative approach as a method of investigation. This work relies on classic works of experts in the broader discipline of globalization and conflict resolutions, the essence of which is to clearly define ways of ensuring absolute peace in Nigeria’s north-central zone. The paper observes that guaranteeing peace-building requires the adoption of both vertical and horizontal approaches as templates for the realization of peace objectives.
Recently, wireless sensor networks (WSNs) have been deployed for a wide variety of applications, including military sensing and tracking, patient status monitoring, traffic flow monitoring, where sensory devices often move between different locations. Securing data and communications requires suitable encryption key protocols. In this paper, we propose a certificateless-effective key management (CL-EKM) protocol for secure communication in dynamic WSNs characterized by node mobility. The CL-EKM supports efficient key updates when a node leaves or joins a cluster and ensures forward and backward key secrecy. The protocol also supports efficient key revocation for compromised nodes and minimizes the impact of a node compromise on the security of other communication links. A security analysis of our scheme shows that our protocol is effective in defending against various attacks.We implement CL-EKM in Contiki OS and simulate it using Cooja simulator to assess its time, energy, communication, and memory performance.
ABSTRACT The 2006 International Telecommunication Union (ITU) Radio World Conference treaty concluded that all countries should migrate from analogue to digital terrestrial television by June 2015, starting with region one countries, comprising Africa, Europe, the Middle East and the Republic of Iran (Agona & Otim, 2012). The purpose of this research was to explore the technology adoption model (TAM) to address challenges associated with digital terrestrial television migration, and analyse the readiness of South Africa to migrate. A quantitative research was conducted in order to determine the relationship between dependent and independent variables. Digital television offers many benefits for broadcasters, network operators, spectrum regulators, and consumers. In most countries, the transition was slower than expected, even though most European countries managed to migrate. The digital migration is not an easy transition and analogue switch-off can also be much more difficult. Studies have shown that analogue switch off (ASO) needs to be carefully planned and well budgeted for, and it also needs a good publicity campaign which must involve all relevant stakeholders, such as broadcasters, viewers, manufacturers, network operators, manufacturers and retailers. Even though studies conducted previously identified obstacles of digital migration to include; a) lack of awareness b) lack of information, c) influence of politics and d) influence of corruption.
The 2019 coronavirus (COVID-19) pandemic is spreading worldwide, with a spectacular increase in death missing any effective therapeutic treatment up to now. Molecular docking is a recognized computational tool to assist in early drug discovery and development. Molecular docking analysis was carried out using 2-(4-(aminomethyl)phenyl)isoindoline-1,3-dione Schiff base conjugates with SARS-CoV-2 protease enzyme and COVID-19 main protease in apo form 6M03). The compounds with the best normalized docking scores to protease enzyme (6LU7) were ARG3 (-8.1 kcal/mole), ARG7 (-8.1 kcal/mole) and ARG6 (-8.0 kcal/mole). The best docking ligands for main protease in apo form (6M03) were ARG7 (-8.7 kcal/mole), ARG6 (-8.6 kcal/mole) and ARG3 (-8.4 kcal/mole). The structural similarity between these conjugates inspired us to perform in silico studies to check their possible binding interactions with essential SARS-CoV-2 proteins. These studies provide insight into the potential binding between Schiff base derivatives and SARS-CoV-2 proteins to provide an insight for finding an effective therapy. Finally, ADMET calculations were performed for the Schiff base compounds to predict their pharmacokinetic profiles.
Background: This study investigated the utilization of consumer health informatics in health promotion among the staff of tertiary institutions in Rivers state. Subjects & Methods: A cross-sectional descriptive research design was used. Two research questions guided this paper. The population of this paper comprised all the 13,046 staff of tertiary institutions in Rivers state. A sample of 1226 staff was drawn using multi-stage sampling techniques. An instrument titled, “Utilization of Consumer Health Informatics in Health Promotion Questionnaire” (UCHIHPQ) was adopted for data collection. The instrument was validated and reliability yielded an index of 0.80. Mean and Standard Deviation statistics were used to answer the research questions. The statistical analysis was performed with the use of SPSS v23. Results: The result revealed among others that to a very large extent, the respondents accepted that consumer health informatics was used to improve their nutritional and physical health status. Conclusion: It was therefore concluded and recommended among others that staff of tertiary institutions in Rivers state should regularly use intelligent informatics applications to attain a healthy balance between self-reliance and seeking professional help concerning nutritional and physical health matter
Parkinson’s disease, first described by James Parkinson in 1817, is a neurodegenerative ailment resulting from the damage of nerve cells in the brain. It is a chronic, progressive, neurodegenerative disorder with an estimated prevalence of 31 to 328 per 100,000 people worldwide. It is estimated that more than 1 percent of the population over age 65 are afflicted with Parkinson’s disease; incidence and prevalence increase with age. There are numerous unanswered questions regarding the diagnosis and management of Parkinson’s disease. Worsening mobility, causing problems with activities of daily living, pain and communication problems due to rigidity of facial muscles, are the main reasons of their decreasing quality of life. This study is focused on the role of psychological variables, which could be associated with quality of life in PD patients. After their identification a discussion about opportunities of improvement patient’s quality of life can be opened. Current drug therapies for human PD with Levodopa or various dopamine receptor agonists offer symptomatic relief and appear to have little effect on the neurodegenerative process. More than 50% of patients with PD treated over 5 years with Levodopa will develop complications such as motor fluctuations and dyskinesia’s. In this scenario, slowing the progression of PD through neuroprotective or restorative therapy is a major focus of research. From a pharmacologic standpoint, current strategies involve interrupting the cascade of biochemical events that leads to death of dopaminergic cells. The significance of many indigenous medicinal plants and their phytoconstitutents in the management of Parkinsonism with minimal side effect profile arise in this context
In this article, we study an Inventory Routing Problem with deterministic customer demand in a two-tier supply chain. The supply chain network consists of a supplier using a single vehicle with a given capacity to deliver a single product type to multiple customers. We are interested in population-based algorithms to solve our problem. A Memetic Algorithm (MA) is developed based on the Genetic Algorithm (GA) and Variable Neighborhood Search methods. The proposed meta-heuristics are tested on small and large reference benchmarks. The results of the MA are compared to those of the classical GA and to the optimal solutions in the literature. The comparison shows the efficiency of using MA and its ability to generate high quality solutions in a reasonable computation time.
Background Predisposing factors for chronic obstructive pulmonary disease (COPD) comprise endogenous genetic factors and exogenous factors such as positive and negative smoking, air pollution, inhalation of dust, and work-related chemicals. Because only a small percentage of smokers develop COPD, it is thought to arise as an outcome of environmental harm and a host’s response system, which boosts the tendency of the disease to arise. Objective To clarify the effect of smoking on the level of oxidant–antioxidant in patients with COPD. Patients and methods Thirty patients with COPD (20 smokers and 10 nonsmokers) and 40 healthy individuals (18 smokers and 22 nonsmokers) participated in this study. The investigations included measurement of malondialdehyde (MDA), superoxide dismutase (SOD) activity, catalase (CAT) activity, glutathione peroxidase (GPx), glutathione reductase (GR), vitamin C, and glutathione (GSH) content. Results SOD, CAT, GPx, GSH, GR, and vitamin C were significant lower (P<0.0001) among patients with COPD (smokers and nonsmokers) than in the control group, whereas the MDA levels were elevated (P<0.0001) in patients with COPD (smokers and nonsmokers) when compared with the control group. Moreover, the values of SOD, GSH, and GPx were significantly lower (P<0.001) in smokers with COPD as compared with nonsmokers with COPD. Finally, there was no significant difference in the level of MDA between patients with COPD (smokers and nonsmokers). Conclusion There is a significant reduction in the level of some antioxidants (SOD, GSH, and GPx) in smokers with COPD compared with nonsmokers with COPD, but other antioxidants (CAT, GR, and vitamin C) did not change significantly, whereas the oxidant levels (i.e., MDA) were relatively convergent in patients with COPD (smokers and nonsmokers). This, in turn, points to the modest role of smoking in the causation of oxidant–antioxidant imbalance in this diseas