Mediterranean Journal Of Pharmacy And Pharmaceutical Sciences

Pharmacotherapy and associated risk factors for pulmonary tuberculosis

  • Authors Details :  
  • Roba F. Sherif,  
  • Nagat M. Saeed,  
  • Fathi M. Sherif

1 Article Views Research reports

Tuberculosis is communicable disease which is common and often deadly infectious disease caused by mycobacterium tuberculosis. Tuberculosis continues to be a major public health problem in the world. The aim of this study is to assess prevalence and associated risk factors of pulmonary tuberculosis. Treatment and development of multidrug-resistant tuberculosis were also considered. Drugs for Pulmonary tuberculosis confirmed cases used in calculating tuberculosis prevalence in Libya which is obtained from archive department of Abu Seta Hospital. Data obtained from 427 files during 2019 determine the incidence and epidemiology of tuberculosis in Libya. For a total of 427 confirmed cases of pulmonary tuberculosis, about 75.0% of the cases were male and most of the patients (55.0%) were within the age group of 20 - 40 years old. Of the study patients, 114 patients (26.7%) were viral infected and most of the viral infected cases were in the age group of 20 - 40 years and the majority of this age group patients (n = 41, 53.2%) were infected with HIV/HCV, while the least percentage in this group age were infected with HIV/HBsAg (01.3%). Among 427 cases, 73 cases (17.1%) were comorbid with other chronic diseases. Of the 73 cases, 54 cases (74.0%) were diabetes mellitus whereas only 1.4% of them had bronchial asthma, Parkinsonism and renal failure. The drug therapy of active tuberculosis disease needs combination chemotherapy to escape the selection of naturally occurring drug-resistant mutants. Amongst current anti tuberculosis drugs, the rifamycins hold the highest potential for shortening treatment and improving effects. Prevalence of smear positive tuberculosis and bacteriologically confirmed that a high rate of tuberculosis among unemployed population. This study reported that the highest incidence rate is found in people who are smokers.

Article DOI & Crossmark Data

DOI : https://doi.org/10.5281/zenodo.5806168

Article QR Code

Pharmacotherapy and associated risk factors for pulmonary tuberculosis QR Code

Article Subject Details


Article Keywords Details



Article File

Full Text PDF




More Article by Mediterranean Journal of Pharmacy and Pharmaceutical Sciences

The perspective of covid-19 vaccines

The current covid-19 is now endemic on everycontinent and becomes the most challenging outbreaks over centuries, thus millions of people have been infected with the novel coronavir...

Mokhtar r. haman: a dedication to his memory

It is with more sorrow and tremendous sadness we remember the death of our colleague the libyan pharmacist, professor mokhtar ramadan haman, at his home in tripoli, libya after lon...

In silico studies of 2-(4-(aminomethyl)phenyl)isoindoline-1,3-dione schiff base derivatives as potential inhibitors against main protease covid-19 enzyme

The 2019 coronavirus (covid-19) pandemic is spreading worldwide, with a spectacular increase in death missing any effective therapeutic treatment up to now. molecular docking is a ...

Phytochemical screening and structure elucidation of isolated compounds from convolvulus dorycnium plant originated from west of libya

Plants are an ancient source of medicine due to the presence of bioactive molecules of various compounds in their different parts. convolvulus dorycnium plant belongs to the family...