Incidence of gestational hypertension among pregnant women (2006-2015) in enugu state, southeast nigeria: a retrospective study

Background: Gestational hypertension (GHTN) is defined as a new rise in blood pressure (BP) ≥140/90 mm Hg, presenting at 20 weeks gestation without significant proteinuria. Worldwide, 4.4%-15% of all pregnancies are complicated by HTN. The aim of this study was to determine the incidence of GHTN among pregnant women in Enugu State, Southeast Nigeria with a view to improving and strengthening antenatal services in the State to help reduce the proportion of maternal mortality and fetal outcomes attributable to GHTN and reduce the overall prevalence of HTN in the country. Methods: Records of BP, biodata and laboratory investigations (urinalysis, full blood count) of women who attended antenatal clinics in six selected state hospitals (2006-2015) were examined. Data were analyzed as proportions, t-test, ANOVA and Pearson product moment correlations using Maxstat (version 3.60) statistical software. Results: The overall incidence of GHTN was 5.9% with annual fluctuations with peaks in 2010 and 2014. There were significant differences in incidence among the age groups (<20>35 years) (p<0 p=0.0016).>35 years) and GHTN (r=0.932, p=0.0069). Between parity and GHTN, there was also positive, strong and significant correlation (r=0.813, p=0.0491). Conclusions: With an incidence of GHTN at 5.9%, there is need to improve and sustain adequate antenatal services in order to help reduce the proportion of the country’s maternal mortality attributable to hypertensive disorders of pregnancy.

Emmanuel umegbolu

School enrolment growth and carrying capacity of universities in imo state, nigeria

The study examined the impact of school enrolment growth on the carrying capacity of universities in Imo State, Nigeria. Three research questions and hypotheses guided the study. The study adopted the descriptive survey design with a population of 2,929 academic staff in the two public universities in Imo State. The sample size was 352 representing 12% of the population drawn using stratified random sampling technique. An instrument titled ‘School Enrolment Growth and Carrying Capacity of Universities Questionnaire (SEGCCUQ)’, structured on the 4 point scale, validated by experts and with reliability index of 0.84 was used for data generation. Mean and standard deviation were used to answer the research questions while z-test was used to test the hypotheses at 0.05 alpha level. Among others, the study revealed that factors such as natural increase of population, influx of migrants, enforcement of compulsory education, raising of school-leaving age, increased enrolment of girls and so on influence school enrolment growth that bear on the carrying capacity of universities. It was recommended among others that the factors should help the governments and institutions to forecast enrollment more effectively likewise permit them to make adjustments to meet current or future enrolment.

FXintegrity Publishing Fxintegrity publishing

Antiemetic activity of leaves extracts of five leguminous plants

The current study is carried out to evaluate the antiemetic activity of methanol extracts of five leguminous plants leaves viz., Cassia siamea Lamk., Cyamopsis tetragonoloba Taubert., Delonix regia Rafin., Samanea saman Merr. and Vigna trilobata Verdc. at a dose of 150 mg/kg body weight orally, using a chick emesis model. Emesis was induced in male chicks by the oral administration of copper sulphate (50 mg/Kg body weight). The antiemetic activity was determined by calculating the mean decrease in the number of retching as compare with the control. All the extracts showed antiemetic activity when compared with standard drug chlorpromazine (150 mg/kg body weight orally). Among all extracts, Delonix regia showed the highest (96.74%) and Cassia siamea lowest (18%) antiemetic activity.

Dr. Salman Ahmed Dr. salman ahmed

The untethered soul pdf

The seeds for this work were planted many years ago when Linda Bean wastranscribing some of my lectures and encouraged me to write a book. Shepatiently labored through years of archived material until it was time for me tobegin writing. Her commitment and dedication to this project are deeplyappreciated.Once I began writing, Karen Entner assisted me by organizing materials,making content suggestions, and maintaining the manuscript. We workedtogether to edit version after version until the flow of words brought a sense ofpeace to the heart, mind, and soul. Her dedication and heartfelt work are muchappreciated and one of her lifelong dreams comes to fruition with the publicationof this book. “This above all: to thine own self be true, and it must follow,as the night the day, thou canst not then be false to any man.” —William ShakespeareShakespeare’s age-honored words, spoken by Polonius to his son Laertes in ActI of Hamlet, sound so clear and unambiguous. They tell us that to maintainhonest relations with others we must first be true to ourselves. Yet if Laerteswere to be totally honest with himself, he would realize that his father may aswell have told him to catch the wind. After all, to which “self” are we to be true?Is it the one that shows up when we’re in a bad mood, or the one that is presentwhen we feel humbled by our mistakes? Is it the one who speaks from the darkrecesses of the heart when we’re depressed or upset, or the one that appearsduring those fleeting moments when life seems so fanciful and light?From these questions we see that the concept of “self” may turn out to be abit more elusive than initially presumed. Perhaps if Laertes could have turned totraditional psychology, it would have shed some light on the subject. Freud(1927), the father of psychology, divided the psyche into three parts: the id, theego, and the superego. He saw the id as our primal, animal nature; the superegoas the judgment system that society has instilled within us; and the ego as ourrepresentative to the outside world that struggles to maintain a balance betweenthe other two powerful forces. But this certainly would not have helped youngLaertes. After all, to which of these conflicting forces are we to be true?Again we see that things are not always as simple as they seem. If we dare tolook past the surface of the term “self,” questions arise that many people wouldrather not ask: “Are the many aspects of my being all equally part of my ‘self,’or is there only one of me—and if so, which, where, how, and why?”In the following chapters, we will undertake a journey of exploration of“self.” But we will not do so in a traditional manner. We will neither call uponthe experts in psychology, nor upon the great philosophers. We will not argueand choose between time-honored religious views, or resort to statisticallysupported surveys of people’s opinions. We will, instead, turn to a single sourcethat has phenomenal direct knowledge on the subject. We will turn to one expertwho, for every moment of every day of their life, has been collecting the datanecessary to finally put this great inquiry to rest. And that expert is you.

Kamal Singh Kamal singh

Assessment of health-related quality of life and medication adherence in tuberculosis patients

Tuberculosis (TB) is an infectious disease caused by bacteria called Mycobacterium tuberculosis. The disease mainly affects lungs and causes pulmonary tuberculosis. It can also affect intestine, meninges, skin, bones and other tissues of the body. Although the drugs alone can cure TB, it still remains a major public health problem worldwide. The aim of the study was to assess the quality of life and medication adherence in TB patients. The Quality of life was assessed using SF-36 in patients receiving DOTS treatment in initial or continuous phase while the medication adherence was analyzed using Morisky Green Levine Scale. Subjects were also counselled about their disease during their first visit and a follow up was done after a month. A total of 152 subjects were enrolled in the study of which majority of the subjects had Pulmonary TB (55.26%). Diabetes was found to be the most common comorbidity followed by HTN. The average Physical Component Summary (PCS) and Mental component summary (MCS) were found to be 44.34 and 39.60 respectively. Females had a better quality of life scores compared to males. High adherence was seen in 32.24% of patients while 28.29% had low adherence. Follow up was done for 135 subjects. 15 subjects defaulted and 2 of them died. There was a significant increase in the QoL scores and medication adherence after one month. A significant association was found between the Physical functioning (p=0.001) and emotional wellbeing (p=0.01) with Duration of treatment indicating that subjects who had completed more than one month of their treatment had marked improvement in Physical functioning and emotional well-being scores

Dr mahendrakumar r

Cerebrospinal fluid leakage post-lumbar puncture: a narrative review

Cerebrospinal fluid (CSF) is critical in maintaining brain interstitial fluid balance and providing hydromechanical protection. Lumbar puncture (LP) is a common invasive procedure for obtaining CSF samples to evaluate central nervous system infections and cancers and measure intracranial pressure. While LP is generally considered safe, it is associated with both minor and major complications. Post-LP meningitis occurs in approximately 50% of spinal anesthesia cases and 9% of diagnostic LPs. Additionally, over 70% of diagnostic LPs result in minor bleeding, which can lead to serious outcomes such as spinal epidural hematoma, nerve damage, or paralysis. Significant consequences of LP include headaches and hearing loss; however, other rare complications, such as cerebral herniation and CSF leak syndrome, must be considered carefully. This review synthesizes findings from multiple studies published in PubMed, Google Scholar, and Scopus, highlighting the need for further research on the complications and interventions related to this commonly performed procedure.

Karishma Karishma

Business law - status of law in the context of the uk

This paper attempts to review the status of law in the context of the UK. The critical areas reviewed in the study included the nature of the legal systems within the UK, focusing on the role played by law within the community and the sources of law. In the second task, the connection between law and the business world is established, trying to ascertain the role of company law, employment laws, the law of contract, and the intellectual property to the businesses. Task three assessed the existing laws regarding the different types of business organizations created in the country, concentrating on the legal requirements for establishing the same. The last task focused on the recommendation that the study makes in conclusion regarding the dispute resolution processes available in the current business world.

Zamzam Abdelazim Zamzam abdelazim

An assessment of the underground water collected from ogbete area enugu state, nigeria

Water contamination has become a global challenge which must be tackled. This study examined the contamination level of water in four locations at Ogbete area Enugu state. Carters street had the highest pH of 5.23 which is below the WHO standards limits for drinking water. The conductivities ranged from the highest conductivity 1445 μs/cm, which is below the WHO limits (8-10,000 μs/cm), TDS (1000 mg/l., TSS (WHO (500 mg/l). For alkalinity, the four locations were all below the (150 mg/l) standard set by World Health Organisation. Results showed that most of the physicochemical, biological and heavy metals parameters considered in this study were significantly above the permissible or allowed by WHO. It is therefore recommended that the water should be treated before use.

OKECHUKWU OBED CHUKWUEMEKA Okechukwu obed chukwuemeka

Assess the premenstrual symptoms and coping strategies among adolescent girls

Menstruation is a normal physiological impact on each girl’s life. Menstruation is monthly uterine bleeding for 3-5 days after every 28 days from puberty till menopause. A change in mood, behaviour, appearance of some abnormal vague symptoms is often noticed in the second half of the cycle. Symptoms are severe enough to disturb the life cycle of a woman called premenstrual syndrome (PMS). The study aimed to assess the premenstrual symptoms and coping strategies among adolescent girls. The majority of the students suffered from premenstrual syndrome. Objective: to assess the premenstrual symptoms and coping strategies among adolescent girls. Methodology: A nonexperimental descriptive research design was adopted in this study. Non probability convenient sampling technique was used to select the sample size of 30 adolescent girls. The assessment of premenstrual symptoms and coping strategies was carried out using a self-reported Likert’s rating scale. Data was analyzed by using descriptive and inferential statistics. Result: Majority (93.3%) of the samples sometimes had physiological and psychological problems, 90% of them had behavioural symptoms. Majority (43.3%) of the samples always followed coping strategies and 16.7% of the samples sometimes followed coping strategies and 40% never followed any coping strategies. Conclusion: PMS was common among students at 18-24 years. The most common physical symptoms experienced by adolescent girls were headache, backache and lower abdominal pain. Adolescent girls used coping strategies as taking hot / cold drinks, do not express anger to others, and turn to study and forget things, hearing music and taking medications. Keywords: Premenstrual Symptoms, physiological, psychological & behavioural symptoms, Coping Strategies, Adolescent Girls.

Elsi Queen Elsi queen

Digital governance initiatives in telangana: a comprehensive overview

Digital governance has become a cornerstone of modern administrative systems, enabling governments to provide efficient and transparent services to citizens. Telangana, a state in southern India, has emerged as a pioneer in implementing various digital governance initiatives to enhance service delivery and promote inclusive development. This paper provides a comprehensive overview of the digital governance initiatives undertaken by the Government of Telangana, highlighting their objectives, key features, and impact on governance. The paper begins by outlining the context of digital governance in Telangana, emphasizing the state government's commitment to leveraging technology for governance reforms. It then delves into specific initiatives across various sectors, including e-governance, digital infrastructure, citizen services, and smart city projects. Each initiative is analyzed in terms of its objectives, implementation strategies, technological components, and outcomes. Key initiatives such as the Telangana State Portal, T App Folio mobile app, MeeSeva portal for e-services, and the T-Fiber project for broadband connectivity are discussed in detail. Additionally, the paper examines the integration of emerging technologies like artificial intelligence, blockchain, and Internet of Things (IoT) in governance processes to improve efficiency and transparency. Furthermore, the paper evaluates the impact of these initiatives on governance outcomes, including enhanced service delivery, increased transparency, and improved citizen engagement. It also identifies challenges faced in the implementation process and offers recommendations for overcoming them. Overall, this paper provides valuable insights into the digital governance landscape in Telangana, showcasing the state's efforts in harnessing technology to build a more efficient, responsive, and citizen-centric administration. By documenting the successes, challenges, and lessons learned, it aims to inform policymakers, researchers, and practitioners interested in digital governance and public administration reform.

Dr Gedam Kamalakar Dr gedam kamalakar

Optimum decimation and filtering for reconfigurable sigma delta adc

The Sigma Delta Analog to Digital Converter (SD-ADC) with passive analog components is presented. The digital blocks required for creating the samples with required sample rate and word length from the 1 bit ADC output are presented. The digital filters are initially modeled in MATLAB Simulink and validated in frequency domain. Further they are synthesized to Xilinx Spartan-6 FPGA technology. The synthesis results report clock speeds up to 300MHz. The simulation results are used to validate the principle and verify the performance of SD-ADC. The results demonstrate a promising technology area of realizing SD-ADC as a reconfigurable block on FPGA to meet several signal processing applications with sampling rates up to few hundreds of KHz

P.a. harsha vardhini

Computer fundamentals pdf

Computer as a revolution left no area of life untouched in the present world. It is of tremendous help in all field of life. Hence, the knowledge of computer is a necessity for existence of everybody in this global village. The invention of computer has transformed our simple manual works to sophisticated life of automated works to meet the global demand for the higher productivity and increased efficiency with high precision. Computer is increasingly becoming compulsory in nearly all fields of studies, not because of anything but its accuracy and versatility in processing data. Many tasks at home or office are being automated rapidly with computer. Thus it is becoming apparent that in whatever discipline or working sector, the computer is now a very vital tool for efficiency improvement and precision of job or task execution. This is designed to meet the prerequisite need of everybody that are interested and wish to know about computers science and computing in general. A computer is an electronic device, operating under the control of instructions stored in its own memory. These instructions tell the achine what to do. The computer is capable of accepting data (input), processing data arithmetically and logically, producing output from the processing, and storing the results for future use. Most computers that sit on a desktop are called Personal Computers (PCs). The "computer" is an ensemble of different machines that you will be using to get your job done. A computer is primarily made of the Central Processing Unit (usually referred to as the computer), the monitor, the keyboard, and the mouse. Other pieces of hardware are commonly referred to as peripherals. In everyday life activities, we process data or encounter cases of data processing. A typical example of data processing is the generation of statement of student result from the marks score in an examination and continuous assessment. It is essential to know that information is as good as the data from which it is derived, and the transformation process which they are subjected to. Meaningless data or inappropriate processing produces wrong information. Thus computer gives you results corresponding to what data you supply and how you process it (i.e. ëgabbage- in, gabbage-outí) Summarily, the intelligent performance of a computer depends on correctness of input data and the intelligence performance of the human being that drives it.

Kamal Singh Kamal singh

Biodiversity census and its significance in india: a scrutiny

Conservation of Biodiversity is an activity must carry out by all individuals in the world to share the benefits derived from biodiversity. It is a critical task to conduct the biodiversity census and conservation (Biodiversity C & C or Biodiversity C2). Throughout the world several Governament and Non-Governamental organizations work together as a unit to maintain our biodiversity in safe mode. India is a mega diverse country with rich biodiversity. The development of modern science and technologies have increased the value of biodiversity and associated traditional knowledge. To save valuable biodiversity and traditional knowledge of our country, National biodiversity board and State biodiversity board constantly involved in this approach and biodiversity law's support to conserve the living diversity.

Veerabhadraswamy AL Veerabhadraswamy al

Nutritional evaluation of processed cocoyam, soya bean flour, and their blends by feeding trials using albino rabbits

Food nutrients are essential for the growth and development of human. In several parts of the world, Cocoyam (Colocasia esculenta), is a tropical root crop cultivated for food formulations and consumption by humans. This study was conducted to assess the nutritional evaluation (weight gain, protein efficiency ratio, net protein retention, and biological value) of the processed cocoyam, soya bean (Glycine max) flours and their blends by feeding trials using Albino rabbits. The sun-dried samples were milled to size (sieve with 25 µm aperture size) to obtain homogenous flours. Blends were obtained with various ratios according to the percentage of soya bean/cocoyam flours. The biological value, protein efficiency ratio, and net protein retention were analysed using standard methods for the calculations. Net protein retention of soya bean flour was higher than that for cocoyam flour. The highest biological value was given by the 50% blend, while the lowest was given by the control diet. The higher the protein efficiency ratio values, the higher the protein quality. The highest protein efficiency ratio value was given by soya bean flour, while the lowest value was from Cocoyam flour. The best blend of Cocoyam and soya bean flours obtained based on chemical and nutritional evaluations was the 50% blend of soya bean and Cocoyam flours.

Mediterranean Journal of Pharmacy and Pharmaceutical Sciences Mediterranean journal of pharmacy and pharmaceutical sciences

Efficacy and safety of generic alendronate for osteoporosis treatment

Background: While osteoporosis increases the risk of fragility fractures, bisphosphonate has been proven to increase bone strengthand reduce the risk of vertebral and non-vertebral fractures. In addition to its efficacy, substituting the brand with generic medication isa strategy to optimize healthcare expenditures. This study aimed to evaluate the efficacy of generic alendronate treatment and assesspotential adverse events in patients with osteoporosis.Materials and Methods: A retrospective review was conducted on 120 patients who met the indications for osteoporosis treatment,received weekly generic alendronate (70 mg) for >1 year, and underwent evaluation through standard axial dual-energy X-rayabsorptiometry (DXA). The outcomes of this study were the percent change in bone mineral density (BMD) at the lumbar spine,femoral neck, and total hip after one year of treatment. The major adverse events occurring during medication that led to thediscontinuation of drug administration were documented.Results: Most patients were female (96.7%) with an average age of 69.0 ± 9.3 years. The percent change in BMD increased at all sitesafter one year of generic alendronate treatment (lumbar spine: 5.6 ± 13.7, p-value <0.001; femoral neck: 2.3 ± 8.3, p-value = 0.023;total hip: 2.1 ± 6.2, p-value = 0.003), with over 85% of patients experiencing increased or stable BMD. Three patients discontinued themedication due to adverse effects: two had dyspepsia, and one had persistent myalgia.Conclusion: Generic alendronate may be considered an effective antiresorptive agent for osteoporosis treatment with a low incidenceof adverse effects

Saran malisorn Saran malisorn

Training and development in north eastern karnataka road transport corporation : a study

Personnel Department is the predominant component of HRD unit of North Eastern Karnataka Road Transport Corporation (NEKRTC), though HRD has been identified and designated as a separate Department. Basically the existing Personnel Department is qualified to be called HR Department OR even a better name would be Human Resources Management Department, since it would correctly reflect the comprehensive and all inclusive nature of the functions of the existing Personnel Department, which covers all features of Human Resources Management, namely Forecast of requirement of Human Resources, Planning for Recruitment, In-service care Co-ordination, Control and Regulation as also Retirement and all matters related to Personnel Administration. It should be its function to plan for training appropriately along with recruitment of personnel from all the Departments. The present Human Resource Development. Is ill-equipped and does not have the comprehension of concept and perception of HRD.

Dr.Kailaspathi vishwakarma Dr.kailaspathi vishwakarma

Evaluation of self-medication with antibiotics in libyan community

Self-medication of antibiotics is an irrational use of drugs, contributing to microbial resistance, increasing health care cost and higher mortality and morbidity. This study was aimed to assess self-medication with antibiotics without a medical prescription in the community of Libya. This is a cross-sectional study conducted from June to December, 2022 and the total number of participants was 200. The design of the study and sample size were modified according to the proficiency of pharmacists and the medical and non-medical population of Libya. The questionnaire was developed in English and Arabic language and was distributed through social media platforms. The questions were used after a thorough literature search and assessing the validity and reliability. The significant signs regarding reasons for the treatment by self-medication drugs of antibiotics, because of its various drugs of antibiotic by pharmacist (n = 80, 40.0%) and family (n = 90, 45.0%) compare with experience and physicians by used prescription was 13 (06.50%) and significant sings regarding by nasal congestion self-medication of various antibiotics (n = 100, 50.0%). This sign must be practiced based on a previous physician’s prescription. The antibiotics are often self-administered as patient feel that they will save money and time but this can lead to substantial adverse drug reaction, antibiotic resistance, treatment failure and drug-related toxicity. This study respondent's medical and non-medical public of Libya who should be relatively informed and educated about the risk of treatment by self-medication of antibiotics with the development of resistance.

Mediterranean Journal of Pharmacy and Pharmaceutical Sciences Mediterranean journal of pharmacy and pharmaceutical sciences

The russian crisis communication response beyond mh17 tragedy

Effective crisis communication response through using the proper strategies is critical to cope with crises and to protect the reputation and existence of the involved parties. Usually, aviation accidents receive great attention from the media and the public. Malaysia Airlines Flight 17 (MH17) which was shot down over eastern Ukraine on 17 July 2014 during its scheduled flight from Amsterdam to Kuala Lumpur received global attention. This attention was due to the involvement of several countries either at the level of the countries of victims or the countries accused of the attack. Image repair theory proposed by William Benoit, the widely used in crisis communication response was implemented in this study. The Russian response to the international accusation, especially from the Western world on supporting the attackers of MH17 has been examined in this study. This study implemented both quantitative and qualitative content analysis to achieve its aims. A total of 306 news stories from the online New Straits Times newspaper Website from the years 2014 to 2019 were analysed. A total of 191 strategies were included in 123 news stories since some stories combined more than a strategy. Out of 191 strategies, 43.5% were simple denial, followed by shift the blame and attack accuser with 35.1% and 21.5% respectively. The results revealed that the image repair effort by Russia was effective and successful.

Mohammed Fadel Arandas Mohammed fadel arandas

The potential of endemic medicinal plants in the central regions of abyan governorate, yemen for sustainable pharmaceutical applications

The potential of endemic medicinal plants in Yemen for sustainable pharmaceutical applications is home to a diverse and unique flora, with a significant proportion of endemic and near-endemic species that are traditionally used in folk medicine. This study documents 16 medicinal plant species from Abyan Governorate, Southeastern Yemen, and analyzes their traditional therapeutic uses and the extent to which they have been phytochemically investigated. The majority of these species are used to treat skin diseases, wounds, and burns. However, the findings indicate that 56.3% of these plants have not yet been studied for their active compounds. The Asclepiadaceae family was the most represented among the studied taxa, yet remains largely chemically unexplored. The study emphasizes the importance of preserving ethnobotanical knowledge and recommends future phytochemical screening and pharmacological validation of under-researched species for sustainable use in pharmaceutical development.

Mediterranean Journal of Pharmacy and Pharmaceutical Sciences Mediterranean journal of pharmacy and pharmaceutical sciences

Effect of occupational exposure on hematological and biochemical parameters in workers at oil and gas companies

Petroleum refineries are largest chemical industries that are responsible for emission of several pollutants into the atmosphere. Benzene and its metabolites are regarded as the most hazardous compounds that are emitted by petroleum refineries. These contribute to toxic oxidants, which cause many serious health risks to petroleum refineries workers. This study was aimed to analyze the effects of chemical exposure on hematological and biochemical parameters among workers at Zawia oil refinery and Mellituh oil and gas refinery companies. A total of 200 workers participated in this study which consisting of two equal groups (each group: n = 100). The first group consists of petroleum refineries workers and the second group consists of non-oil work civil servants serving were recruited as exposed and control subjects, respectively. The results of blood picture, liver enzymes and kidney functions were compared between the groups. Mean white blood cells counts, platelet counts, and hematocrit count were significantly higher, while the mean red blood cells count was insignificantly changed in petroleum refineries workers. While the mean hemoglobin and corpuscular hemoglobin concentration levels were significantly lower, whereas the mean corpuscular volume and mean corpuscular hemoglobin levels were insignificantly changed in petrol refineries workers. Liver enzymes and renal functions were significantly higher in petrol refineries workers. The present findings indicate that occupational exposure to benzene causes significant alterations in hematological and biochemical parameters and workers are at high risk of developing blood, hepatic or renal related disorders. Protection and frequent medical attention should be given to petroleum refineries workers.

Mediterranean Journal of Pharmacy and Pharmaceutical Sciences Mediterranean journal of pharmacy and pharmaceutical sciences

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