Macrotyloma uniflorum (lam.) verdc., phaseolus lunatus linn., and phaseolus vulgaris linn. seeds: nature’s potential candidates against urolithiasis by virtue of multidimensional pharmacology

Urolithiasis arises from disturbances in the urinary tract's physicochemical balance and hydrodynamic system. Medicinal plants have been known for millennia and are highly esteemed worldwide as a rich source of therapeutic agents for the prevention of various ailments. A comprehensive literature search of antiurolithiatic plants reported worldwide revealed the family Fabaceae with the highest number of cited species. The members, Macrotyloma uniflorum (Lam.) Verdc., Phaseolus lunatus Linn. and Phaseolus vulgaris Linn. have been selected and hidden versatile weapons of their seeds against urolithiasis such as analgesic, antioxidants, astringent, diuretic, emollient, high soluble oxalate contents, insoluble fibers, magnesium, potassium, phytic acid, pyridoxine (vitamin B6), have been discussed on a scientific basis to rationalize the folkloric use.

Dr. Salman Ahmed Dr. salman ahmed

Project risk and procurement management - procurement

Purchasing is one of the key managerial activities in every organisation, its significance having been identified during the 19th century. According to Kasilingham (2012, p.57), the period shortly before the Second World War marked the discovery of the fact that a firm’s success was not so much dependent upon what it was capable of selling but rather on how able organisations were to acquire necessary services together with materials from vendors. This discovery was triggered by a global shortage of virtually all fundamental materials for supporting operations, coupled with an abnormal rise in prices following the First World War. Since that time, purchasing has gained significance for the critical role it plays towards ensuring continuity of production (Hacioglu, 2019 p.265). Worth noting is that purchasing acts as “an interface between suppliers and functional areas within the buying organisation” (Crandall, Crandall & Chen, 2009 p.265). Among some of the functional areas that are influenced by purchasing are finance, marketing, production, and quality assurance (Magad & Amos, 2013 p.225). A vital deduction that can be made from this latter statement is that for the purchasing function to proceed smoothly and make the other functions- and the entire organisation- active, organisations must cultivate and maintain good relationships with suppliers and all other players in the supply chain. In addition, organisations operate in environments that are highly unpredictable; the techniques needed to perform the purchasing function become more refined almost every day due to constant changes in the market (Kasilingam, 2012 p.57). Subsequently, there is a need for managers in organisations to understand and embrace the idea of sustainable procurement.

Mohamed Sorogy Mohamed sorogy

Antiemetic activity of leaves extracts of five leguminous plants

The current study is carried out to evaluate the antiemetic activity of methanol extracts of five leguminous plants leaves viz., Cassia siamea Lamk., Cyamopsis tetragonoloba Taubert., Delonix regia Rafin., Samanea saman Merr. and Vigna trilobata Verdc. at a dose of 150 mg/kg body weight orally, using a chick emesis model. Emesis was induced in male chicks by the oral administration of copper sulphate (50 mg/Kg body weight). The antiemetic activity was determined by calculating the mean decrease in the number of retching as compare with the control. All the extracts showed antiemetic activity when compared with standard drug chlorpromazine (150 mg/kg body weight orally). Among all extracts, Delonix regia showed the highest (96.74%) and Cassia siamea lowest (18%) antiemetic activity.

Dr. Salman Ahmed Dr. salman ahmed

Anti-inflammatory activity of luffa cylindrica

The current study was designed to explore the anti-inflammatory effects of the crude hexane and ethanol extracts of the leaves and male flowers of Luffa cylindrica (L.) Roem., (sponge gourds) to validate its folk use. These extracts produced significant anti-inflammatory effects (p.o.) at doses of 500, 750 and 1000 mg/kg b.w. in carrageenin-induced paw oedema in rats compared to those obtained with indomethacin. The results of the present study provide evidence for the anti-inflammatory properties of the leaves and male flowers of Luffa cylindrica, which have potential therapeutic applications for inflammatory diseases.

Dr. Salman Ahmed Dr. salman ahmed

Indian higher education system: challenges and suggestions

Over the past 20 years, universities have been faced with sustained change, driven by external factors. This has led to the evolution of the teaching and research mission and the creation and rise of the third mission. Such mission extension has led to the emergence of entrepreneurial universities which has seen a move from traditional research and teaching business models, to business models which incorporate a much wider range of activities, to meet stakeholder demands as well as sustaining and growing universities in the era of intense national and international competition. This special issue extends knowledge by providing novel insights into the multidimensional antecedent contextual influences, consequences and implications of university mission expansion. We also provide a foundational research agenda which will help guide future research exploring the changing and expanding university missions and business models. Higher education system plays an important role for the country’s overall development which includes industrial, social, economic etc. Indian higher education system is third largest in the world. The role of Indian higher educational institutes such as colleges and universities in the present time is to provide quality based education in the field of education, research etc to empower youth for self sustainability. This paper includes the key challenges that India is currently facing in higher education and also includes some initiatives taken by the government to meet those challenges.

Dr Gedam Kamalakar Dr gedam kamalakar

Global business environment - healthy eating

This Document addresses the main trends around healthy eating in the global, Latin American, and Peruvian environment related to the proposed business plan. Analysis shows that with an increase in the population around the world it is important for food producing organizations to introduce new food products in order to be in the race of famous food brands. Based on qualitative and quantitative data from various sources, it is possible to know the opportunities for a plant-based burger business. This assignment aims to recognize if there is a favorable evolution for the proposal of this business plan at the different levels of the environment. The brand focused on this assignment in KFC. A plan for introducing green burgers in Peru and other regions of Latin America was developed in this paper.

Zamzam Abdelazim Zamzam abdelazim

Convergent validity assessment in pls-sem: a loadings-driven approach

Assessment of convergent validity of latent variables is one of the steps in conducting structural equation modeling via partial least squares (PLS-SEM). In this paper, we illustrate such an assessment using a loadings-driven approach. The analysis employs WarpPLS, a leading PLSSEM software tool.

Johnny Amora Johnny amora

Screening of salt tolerant and growth promotion efficacy of phosphate solubilizing bacteria.

An attempt was made for screening of salt tolerant against sodium chloride (NaCl) salt and growth promotion efficacy of eight different phosphate solubilizing bacterial (PSB) isolates under in vitro conditions. An efficient isolate which exhibited maximum phosphate solubilization, salt tolerant, Indole-3-Acetic Acid (IAA) production and root colonization potential in maximum concentration of NaCl (7%) was identified as Bacillus cereus based on 16S rRNA sequencing. It was recorded that highest phosphate solubilization in 7% NaCl concentration (70% and 374 μg/mL) in agar plate and broth assay respectively. IAA production was observed to be decreased when salt concentration increases, the isolate showed significant amount of IAA in normal culture media without amendment of NaCl (74.94 μg/mL) and at 7% gradual decrease of IAA production was observed (30 μg/mL). Maximum colonization of isolate in the roots of Zea mays was also observed in the study.

Dr. SARANYA DEVI K Dr. saranya devi k

Early diagnosis of tuberculosis using deep learning approach for iot based healthcare applications

In the modern world, Tuberculosis (TB) is regarded as a serious health issue with a high rate of mortality. TB can be cured completely by early diagnosis. For achieving this, one tool utilized is CXR (Chest X-rays) which is used to screen active TB. An enhanced deep learning (DL) model is implemented for automatic Tuberculosis detection. This work undergoes the phases like preprocessing, segmentation, feature extraction, and optimized classification. Initially, the CXR image is preprocessed and segmented using AFCM (Adaptive Fuzzy C means) clustering. Then, feature extraction and several features are extracted. Finally, these features are given to the DL classifier Deep Belief Network (DBN). To improve the classification accuracy and to optimize the DBN, a metaheuristic optimization Adaptive Monarch butterfly optimization (AMBO) algorithm is used. Here, the Deep Belief Network with Adaptive Monarch butterfly optimization (DBN-AMBO) is used for enhancing the accuracy, reducing the error function, and optimizing weighting parameters. The overall implementation is carried out on the Python platform. The overall performance evaluations of the DBN-AMBO were carried out on MC and SC datasets and compared over the other approaches on the basis of certain metrics.

Dr H Shaheen Dr h shaheen

Insecurity in a democratic state: towards reformulating roles of traditional institutions for enhanced national security in nigeria

The main focus of this paper is to examine the relationship between insecurity in Nigeria and how traditional institutions such as traditional monarchical system can be used as veritable tool to curtail increasing insecurity in a democratic system such as Nigeria. The pervasive nature of insecurity,though,not an entirely Nigerian problem, has been trending of late, andhence, become a huge source of worry for scholars,experts,public commentators and the international community at large.The menace of insecurity finds expression in wanton killings, kidnapping,farmers-herders conflicts, rape, communal clashes, militia activities, ethnic secessionist agitations and many other strands of violence. The multiplier effects of all these challenges have been very devastating in terms of the recent attacks witnessed all over the country in recent times. This study observes that most of the people engaged in some of these atrocities might be well known to traditional rulers in the communities where they come from. This is because traditional rulers are closest to the people. The work is an exploratory study and relies solely on literature and works of experts in the broader field of security studies for investigation. The paper sums up a conclusion and recommends that there is a need for the adoption of both vertical and horizontal approaches to tackle the menace of insecurity, particularly, using the instrumentality of traditional institutions as a point of departure.

Canice Erunke Canice erunke

A study to assess coping strategies adopted by adolescents studying in selected schools of distt. mohali, punjab.

The study was conducted by researcher on Coping strategies adopted among adolescents in selected Schools, Distt. Mohali, Punjab. The main aim of this study was to assess on Coping strategies adopted among adolescents, to find out the association between coping strategies adopted among adolescents with their selected socio demographic variables.Descriptive Research design has been used to assess the Coping strategies among 400 adolescents studying in Golden Bell’s school,Sector-77 and Shemrock School, sector 69, in Distt Mohali,Punjab. The sample was selected by Systematic random sampling technique. Pilot study was conducted on 10% of population and sample consists of 40 adolescents. Data on Coping Strategies adopted among adolescents were collected under two sections, Section A- Socio demographic variables and Section B- Coping Strategies Scale of Prof. A.K. Srivastava to assess coping strategies adopted among adolescents. Data was analyzed through Descriptive and inferential statistical methods. The results showed that majority of adolescents were adopting moderate Coping Strategies.There was significant association between Coping Strategies adopted by adolescents with their selected demographic variable such as Class of study, Occupational Status of Mother and Monthly Family Income.Based on the findings of the study, recommendations were drawn on nursing service, nursing education, nursing administration and nursing research.

Anu sharma Anu sharma

Prevalence of thrombocytopenia during pregnancy among libyan women

Thrombocytopenia is a recurrent hematological disturbance in pregnancy. In pregnant women with thrombocytopenia, the risk of excessive bleeding during or after child-birth is high, particularly when they require a cesarean section, other surgery during pregnancy, labor or in the puerperium period. The objective of this study was to assess the prevalence of thrombocytopenia among pregnant women attending antenatal care service at Tripoli University Hospital, Libya. A cross-sectional analysis was used to determine the prevalence thrombocytopenia in pregnant women attending prenatal care services from July to December, 2020 at Tripoli University Hospital. A structured pretested questionnaire was used to obtain socio-demographic data, nutritional factors, obstetrics and gynecological factors, history and clinical conditions. Venous blood samples were collected for platelet count and other platelet parameters, which determined by using Sysmex automation. A total of 72 participated women; about 40%, 35% and 259% of the participants were in the third, second and first trimester, respectively. The mean number of children that women have was 2, with 2.7% having just one child and 47% having three or more children. This study concluded that the prevalence of thrombocytopenia and mostly with mild form is 8.3% and as being greater among pregnant women living in rural areas. Health care providers should do thrombocytopenia test regularly for every pregnant woman in order to prevent excessive bleeding during pregnancy, especially whom living in rural areas.

Mediterranean Journal of Pharmacy and Pharmaceutical Sciences Mediterranean journal of pharmacy and pharmaceutical sciences

Legumes: an overview

Legumes are the richest source of protein, starch, minerals, and vitamins and are considered the earliest domestic plants. They belong to the leguminosae family, one of the largest and most important families of flowering plants. The present review describes the history, consumption, nutritional aspects, traditional medicinal uses, pharmacology, and commercial aspects of legumes.

Dr. Salman Ahmed Dr. salman ahmed

Geotextile can be worth their cost in pavement

Geotextiles have been successfully used for reinforcement of soils to improve the bearing capacity. In this study geotextile as a tensional material have been used for reinforcement of granular soils. Laboratory California Bearing Ratio (CBR) tests were performed to investigate the load-penetration behavior of reinforced soils with geotextile. Samples of granular soil are selected and tested without reinforcement. Then CBR tests were performed by placing geotextile in one or two layers at various depths in soil sample. The effect of the number of geotextile on the increase in bearing capacity of reinforced granular soil is discussed.

Mayura

Potential antibacterial activity of ethanolic fig and olive leaves extract against enterococcus faecalis

There has been an increasing awareness about the importance of herbal plants in therapeutic uses which are safe, efficient and induce little side effects This study was based on the evaluation of antibacterial activity of ethanolic extracts of the leaves of Oleaeuropaea (Olive tree) and Ficuscarica (Fig tree), alone and in combination, against enterococcus faecalis (E. faecalis) strain using well diffusion method and minimum inhibitory concentration. The results revealed that the Oleaeuropaea leave extract is more potent than the Ficuscarica leave extract against E. faecalis, as the zone of inhibition was 23 mm and 3 mm, respectively. By mixing both extracts, the results showed a slight synergistic effect, as the zones of inhibition were 20 mm, 24 mm, 24 mm and 25 mm for 1:1, 1:3, 1:6 and 1:9 ratios of the Oleaeuropaea leave and the Ficuscarica leave extracts, respectively. The minimum inhibitory concentration for E. faecalis growth was 200 mg/ml for the Oleaeuropaea leave alone, Ficuscarica and mixed with Ficuscarica. The present findings conclude a potent antibacterial activity of the olive and fig leave, and, their potential as a source of drug in the treatment of E. faecalis infections is suggested.

Mediterranean Journal of Pharmacy and Pharmaceutical Sciences Mediterranean journal of pharmacy and pharmaceutical sciences

Apoptosis induced by luteolin in breast cancer: mechanistic and therapeutic perspectives

Background: Breast cancer is a commonly found malignancy worldwide in women, and effective treatment is regarded as a substantial clinical challenge even in the presence of several options. Extensive literature is available that demonstrates polyphenols, the richly introduced phytopharmaceuticals, as anticancer agents. Among these polyphenols, resveratrol, silibinin, quercetin, genistein, and curcumin are reported to have tremendous potential against breast cancer. However, till now, no comprehensive survey has been found about the anticarcinogenic properties of luteolin against breast cancer. Scope and approach: This review targeted the available literature on luteolin in the treatment of breast cancer, its effects in combination with other anticancer drugs, and possible mechanisms. Key findings and conclusion: Lutein's outstanding therapeutic potential in the treatment of breast cancer has been recorded not just as a chemopreventive and chemotherapeutic agent but also complemented by its synergistic effects with other anti-cancer therapies such as cyclophosphamide, doxorubicin, and NSAIDs such as celecoxib and possible underlying mechanisms. Ideally, this review will open new dimensions for luteolin as an effective and safe therapeutic agent in diminishing breast cancer.

Dr. Salman Ahmed Dr. salman ahmed

Attachment levels of fathers and examining the factors affecting

Objective: The present study was conducted to determine the level of attachment of fathers in Karabuk province and the factors affecting them. Materials and Methods: The sample of this descriptive study consisted of 200 fathers who brought their children Karabuk University Education Research Hospital Pediatric Outpatient Clinic and were selected by random sampling method. The socio-demographic data form prepared by the researchers by scanning the literature and the Paternal-Infant attachment Scale, which was validated by Gulec in Turkish, were used. Data forms were applied to the fathers who agreed to participate in the study by face to face interview method. The data were calculated by applying descriptive statistics, percentage calculation and nonparametric tests used in independent variables. Results: It was found that 22.5% of the fathers defined attachment as “happiness”, 5.5% “sacrifice”, 17% “unconditional love” and 55% “I do not know”. The mean score of attachment scores of the fathers was 80.3±8.23. Conclusion: Significant differences were found between the age of the children, duration of marriage, father's age, family type, number of children, and type of delivery. There was no significant difference between defining attachment, infant gender and working status.

Reyhan Aydin Doğan Reyhan aydin doğan

Use and impact of information communication technology based library resources and services in the universities of tamil nadu, india: a study

Libraries play a vital role in providing access to information and fostering lifelong learning in communities. With the rapid advancement of Information Communication Technology (ICT), libraries are embracing digital tools and services to enhance their offerings and extend their reach. In today's interconnected world, the utilization of Information Communication Technology (ICT) resources and services has become imperative for various sectors. This study examines the utilization of ICT-based resources and services by libraries, focusing on key technologies such as digital libraries, online databases, electronic resources, and library management systems. It explores how these technologies enable libraries to expand their collections, improve accessibility, and deliver personalized services to users. The present study is an attempt to examine uses of information communication technology based library resources and services at university of Tamil Nadu. In this paper, the majority of the users' use of ICT based resources and services are study purpose. The majority of the respondents that satisfaction of ICT based resources and services have developed academic skills.

V.murugapandi

Effective communication is the key for healthcare professionals

During COVID-19 pandemic health professional need to develop good communication skills. Good communication skills will lead to professionalism. The information that are given to patients, their families and the community has to be transparent, true and scientifically relevant. The awareness one creates about the pandemic includes mode of infection, transmission, symptoms, vaccines, vaccination, viral heterogeneity and mutations. Such transmission of true information requires proper training of health personnel including the social media in developing good communication skills

Mediterranean Journal of Pharmacy and Pharmaceutical Sciences Mediterranean journal of pharmacy and pharmaceutical sciences

Impact of measuring pneumonia severity index (psi) in the management of community acquired pneumonia in emergency department

Community acquired pneumonia is a prevalent disease in the Emergency Department (ED). The literature reveals that clinical practice could not be related with guidelines recommendations. The aim of this study is to determine the impact of the implementation of the recommendations of the Spanish society of Emergency Medicine in the Hospital Clínico Universitario Lozano Blesa (Zaragoza) ED in the management of community acquired pneumonia. Use of Pneumonia Severity Index (PSI) estimation was used to assess the adherence. This study was carried out from December, 2014 to February, 2015. Data was compared with the previous two months. The indicators management (discharge or admission decision, adequacy and anti-biotherapy) as well as the incidence of PSI estimation before and after the intervention in these parameters were evaluated. 209 patients were included, 97 before the intervention and 112 after the intervention. No significant differences were observed in the calculation of PSI. A significant decrease of admissions was observed after the intervention in the patients in whom the PSI was calculated (68.8% vs. 45.0%, p < 0.05). A greater use of the Observation Room was aimed at those patients in whom the PSI was calculated (06.3% vs. 17.5%, p < 0.05). PSI calculation significantly increased antibiotic prescription adherence (88.9% vs. 75.2%, p < 0.05). There were no modifications in the prescription after the intervention. In conclusion, PSI is a useful and effective measure to achieve a greater adherence to the recommendations. However, despite the positive trend in the use of the PSI and its interpretation, a low-intensity intervention is not sufficient to generalize its use.

Mediterranean Journal of Pharmacy and Pharmaceutical Sciences Mediterranean journal of pharmacy and pharmaceutical sciences

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