Geotextile can be worth their cost in pavement

Geotextiles have been successfully used for reinforcement of soils to improve the bearing capacity. In this study geotextile as a tensional material have been used for reinforcement of granular soils. Laboratory California Bearing Ratio (CBR) tests were performed to investigate the load-penetration behavior of reinforced soils with geotextile. Samples of granular soil are selected and tested without reinforcement. Then CBR tests were performed by placing geotextile in one or two layers at various depths in soil sample. The effect of the number of geotextile on the increase in bearing capacity of reinforced granular soil is discussed.

Mayura

Chemical analysis and analgesic activity of methanol extract of crinium jagus bulb in balb/c mice

Crinum jagus, family- Amaryllidaceae, commonly called river lily is an important medicinal plant used in the treatment of cough. It is an anti-venom agent used among the rural people in south-western Nigeria. The research is aimed to investigate the phytochemical constituents and analgesic activity of Cinium jagus bulb in BALB/c mice. The bulb was extracted with methanol in a soxhlet extractor apparatus. Phytochemical screening was performed according to standard methods. Alkaloid fraction was obtained using separation by extraction and characterized by infra-red (I.R) analysis. Acute toxicity test was done before analgesic activity was determined in BALB/c albino mice using the hot plate model. The result indicated the presence of some bioactive constituents like alkaloids, terpenoids and saponin. I.R bands were observed at 1064.74 cm 1 (C-O) stretch of alcohol; 1415.80 cm-1 (C-H) bend of alkyl groups and 1639.55 cm-1 (N-H) stretch of amine among others. The extract significantly increased the mean latency time of mice on the hot plate when compared with control with 100 mg/kg at 120 minutes. This study indicates that the Crinum Jagus bulb possesses analgesic potential.

Mediterranean Journal of Pharmacy and Pharmaceutical Sciences Mediterranean journal of pharmacy and pharmaceutical sciences

Indonesian crisis communication response after deliberate forest fires and transboundary haze

The issue of deliberate forest fires that set illegally in Indonesia by plantation companies in their slashand-burn forests to clear lands for lucrative palm oil plantations and its caused transboundary haze became a hot issue for discussion. These fires have a negative influence on Indonesia and its neighbourhood countries, especially on their financial and human resources such as environment, economy, properties, and people. Using the right strategies in responding to any crisis determines the success of its management and coping with that crisis with minimal losses. This study aimed to examine the communication crisis response by Indonesia to this crisis by using image repair theory. Also, this study examined how image repair strategies were used by Indonesia. This study analysed the content of news stories from the website of the New Straits Times newspaper. The time frame of this study was from 2015 to 2019. A total of 87 news stories have pertained to Indonesian response, and 37 stories included image repair strategies. Among the strategies of image repair theory, corrective action strategy was the most dominant with 70%, followed by 10.8% for each shift the blame and attack accuser. The least used strategies were mortification and simple denial with 5.4% and 2.7% respectively.

Mohammed Fadel Arandas Mohammed fadel arandas

Predicting bankruptcy of selected telecom service sector by applying altman's z- score model

The objective of the paper is to predict corporate bankruptcy of selected telecom service sector companies. The study ranges for a period of ten years from 2006-2007 to 2015-2016 for three selected telecom service sector. By applying Altman's Z-score model the study analyze the financial position of the companies and suggests the financial components to be concentrated to improve the financial health. Further the study suggests that the companies should regularly estimate Z-score for making strategies to improve their financial position.

Dr. Jeyalakshmi P Dr. jeyalakshmi p

Importance of using basic statistics adequately in clinical research

Justificativa e objetivo: O uso inadequado da estatística básica é o maior responsável peloerro de interpretac ̧ão dos artigos científicos. O objetivo deste artigo de revisão foi rever algunstópicos básicos de estatística para alertar autores e leitores sobre a importância do relatoadequado da estatística básica.

Kamal Singh Kamal singh

Utilization of consumer health informatics in health promotion among staff of tertiary institutions in rivers state

Background: This study investigated the utilization of consumer health informatics in health promotion among the staff of tertiary institutions in Rivers state. Subjects & Methods: A cross-sectional descriptive research design was used. Two research questions guided this paper. The population of this paper comprised all the 13,046 staff of tertiary institutions in Rivers state. A sample of 1226 staff was drawn using multi-stage sampling techniques. An instrument titled, “Utilization of Consumer Health Informatics in Health Promotion Questionnaire” (UCHIHPQ) was adopted for data collection. The instrument was validated and reliability yielded an index of 0.80. Mean and Standard Deviation statistics were used to answer the research questions. The statistical analysis was performed with the use of SPSS v23. Results: The result revealed among others that to a very large extent, the respondents accepted that consumer health informatics was used to improve their nutritional and physical health status. Conclusion: It was therefore concluded and recommended among others that staff of tertiary institutions in Rivers state should regularly use intelligent informatics applications to attain a healthy balance between self-reliance and seeking professional help concerning nutritional and physical health matter

FXintegrity Publishing Fxintegrity publishing

Pharmacy student’s view about covid-19 vaccination in libya

Vaccination hesitation may affect the national efforts to slow down the spread of coronavirus among the population. This study was aimed to explore the views of final year pharmacy students at Faculty of Pharmacy, Elmergib University, Al kums, Libya towards COVID-19 vaccination. The study was conducted before the vaccine becomes available in Libya. A semi-structured questionnaire was distributed on March 14, 2021 to the fourth- year pharmacy students at Elmergib ‎University, Al khums Libya. Results showed a high degree of hesitancy towards vaccination against this virus (52.6%). Student's participants who said they would take the vaccine probably have said that because of their stress that caused by COVID-19 pandemic (47.4%). With regard to the gender, the participants’ views had no significant difference between male and female students on whether to take the vaccine or not (P = 0.825). In conclusion, hesitations towards vaccination and stress caused by student fear from the virus need to be addressed to minimize public reluctant to take the vaccine and to improve the education process during the pandemic.

Mediterranean Journal of Pharmacy and Pharmaceutical Sciences Mediterranean journal of pharmacy and pharmaceutical sciences

Implementation of corporate social responsibility initiatives for tanzania corporations and not-for-profit organizations

The purpose of this study is to evaluate activities of the corporate citizens in Tanzania and find the best way of aligning CSR initiatives to attain mutual benefits between the organizations and general public. A total of 45 organizations, both for profit and not for profit, were engaged in this study from four different industries. The study used semi-structured interview guide to collect data and a focused group discussion was organized. Contents analysis was used to categorize the responses into five major themes, as discussed in the main document. The findings reveal that CSR is still at its initial stage and much has to be done for the corporations to draw the best out it. Keywords Strategic CSR Value Organization and Society

DR. OMARY SWALLEHE Dr. omary swallehe

[pdf] from imist.ma modeling of some cyclic peroxy ketals for their antimalarial activities

In this work a set of some cyclic peroxy ketals were tested for their antimalarial activities. Quantitative structure activity relationship (QSAR) analysis was applied to 20 organic compounds of the above mentioned derivatives using Physicochemical, informational and 2D-autocorelation parameters and modeled their antimalarial activity (logIC 50) values. The multiple regression analysis clearly indicates that 5 BIC, 1 IC, MATS4v and ST parameters yielded the best model having R 2 value of 0.9515. The predictive powers of the models were explained using LOO (Leave-One-Out) Cross validation procedure. The results are also discussed on the basis of ridge regression.

Dr. Shweta Sharma Dr. shweta sharma

Green synthesis of pyrazolo [3,4]-pyrimidine-thiones using ionic liquid 2-methyl-imidazolium-oxalate as potent ehrlich ascites carcinoma receptor antagonists

Objective: Pyrazolopyrimidines are heterocyclic molecules containing nitrogen as the main composition, and hence, they exhibit pharmacological efficacy. They are analogs of purines so that possessing wide applications in the field of medicinal chemistry. The main objective of this study is to synthesize different derivatives of pyrazole-pyrimidine classes by adopting simple methodology as well as by employing green chemistry. The purpose of the synthesis of these molecules is to study the antitumor activity against Ehrlich ascites carcinoma (EAC) cell lines. Methods: After literature studies, it makes us to involve in the research of synthetic organic chemistry, especially to synthesize new compounds of pyrazolopyrimidines. We are reported solvent-free synthesis of pyrazolo [3,4-d]-pyrimidine-thiones through ethyl acetoacetate, hydrazine hydrate, thiourea, and different benzaldehydes. An ionic liquid 2-methyl-imidazolium-oxalate catalyzed the reactions under ultrasonication bath. Both conventional and ultrasonic methods were employed and comparison studies have been made. It was found that ultrasonic method completed the reaction quicker than the conventional method. All the synthesized compounds were confirmed their structures by 1 HNMR, Fourier transform infrared, 13C-NMR, and elemental analysis spectra. The compounds were tested for in vitro anticancer activity against EAC cell lines. Most compounds revealed significant anticancer activity relative to doxorubicin as a positive control with inhibitory concentration (IC50) values. Results: Ultrasonication method is a simple method under which all the reactions were completed at faster time (<7 min) compared to the convention method. Among eight molecules, 8a and 8d completed the reactions at a faster rate. We reported IC50 values of all the molecules, in which 8e and 8g were exhibited excellent potency against EAC cell lines at different concentrations .

Dr Ganesh N Yallappa Dr ganesh n yallappa

The reliability and validity of the vietnamese translation of same-sex marriage scale

Vietnam, in many ways, remains a Confucian nation. The Confucian heritage touches many aspects of people’s lives. In this context, homosexuals do not face severe punishments, but face social stigma or public misunderstanding. Same-Sex Marriage is also not accepted because of limited legal support. Therefore, there is a need to study attitudes towards same-sex marriage in Vietnam. The purpose of this article was to validate a Vietnamses version of the Attitudes Toward Same-Sex Marriage Scale (ATSM) designed by Pearl & Galupo (2007) in a Vietnamese population. The sample in this study was 570 students from six universities in Ho Chi Minh City, Vietnam. The data collection method used was face-to-face questionnaire. Students completed the Attitudes Toward Same-Sex Marriage Scale and other variables in the questionnaire. The respondent’s characteristics also explored through the survey include: gender, what year students are from, religion of the students, what region students are from and their ethnicity. The study found the Vietnamese translation of the ATSM scale both reliable and valid and suitable for research use.

Le Minh Tien Le minh tien

Association of covid-19 severity with vitamin d and blood group

Vitamin D is a hormone which plays a vital role in immune response regulation, including the prevention of inflammation and autoimmunity. Insufficient vitamin D may increase the risk of infection. Vitamin D deficiency is not the only factor linked to an elevated risk of COVID-19 infection. Recent studies have discovered a link between SARS-COV-2 infection risk and blood type. This study was aimed to examine the association of vitamin D and blood groups with the severity of COVID-19. A retrospective study was conducted on 224 confirmed COVID-19 patients, aged between 18 and 89 years old. Patients were divided into three groups (asymptomatic, moderate, and severe cases), and serum 25(OH)D concentration and blood group were analyzed for all the patients. Data of the severe cases were obtained from Souq Althalath Isolation Center, Tripoli, Libya, while moderate and asymptomatic cases were obtained from Abushusha Polyclinic and Aldahmani COVID Filtration Center, during 22nd February 2021 and 28th April 2021 and serum 25(OH)D concentration and blood group were statistically analyzed for all the patients. The percentages of males and females were found to be 47.3% and 52.7%, respectively. Disease severity was distributed as follows: 12.5% asymptomatic, 44.6 % moderate and 42.9% severe. Most of the severe cases had vitamin D deficiency (88.5%). Among the severely ill patients, 39.6% had blood group A and 09.4% had group O, while 22.9%, and 28.1% had blood group B and AB, respectively. In contrast, among the asymptomatic patients, only 7.1% had group A and 85.7% had group O. Overall, the difference in the distribution pattern of blood group in the three severity categories was highly significant (p < 0.001). The prevalence of Rh positivity among asymptomatic, moderate and severe cases was 78.6%, 76.0%, and 60.4%, respectively. This study concludes that insufficient vitamin D levels might influence the severity of COVID-19. COVID-19 patients with blood group A and those who are Rh-positive could be more vulnerable to developing COVID-19 severity.

Mediterranean Journal of Pharmacy and Pharmaceutical Sciences Mediterranean journal of pharmacy and pharmaceutical sciences

A proactive approach to network forensics intrusion (denial of service flood attack) using dynamic features, selection and convolution neural network

Currently, the use of internet-connected applications for storage by different organizations have rapidly increased with the vast need to store data, cybercrimes are also increasing and have affected large organizations and countries as a whole with highly sensitive information, countries like the United States of America, United Kingdom and Nigeria. Organizations generate a lot of information with the help of digitalization, these highly classified information are now stored in databases via the use of computer networks. Thus, allowing for attacks by cybercriminals and state-sponsored agents. Therefore, these organizations and countries spend more resources analyzing cybercrimes instead of preventing and detecting cybercrimes. The use of network forensics plays an important role in investigating cybercrimes; this is because most cybercrimes are committed via computer networks. This paper proposes a new approach to analyzing digital evidence in Nigeria using a proactive method of forensics with the help of deep learning algorithms - Convolutional Neural Networks (CNN) to proactively classify malicious packets from genuine packets and log them as they occur.

Dr. Chandrashekhar Uppin Dr. chandrashekhar uppin

Descriptive analysis to use the community pharmacy by patients and customers

Community pharmacies not only act as sites of drug purchase but also as healthcare setting. The aim of this study is to examine the extent of public’s use of community pharmacy and their reasons of visiting to Sabha, South part of Libya. Thus, a descriptive, cross-sectional survey with self-administered questionnaire was developed and validated. Data was collected during 2019 by registered pharmacists using the self-designed prepared questionnaire for community pharmacies in Sebha. Of all 600 questionnaires were handed during 2020, 462 forms were returned (77%, response rate). The majority of the respondents reported they had visited the community pharmacies at least once in a month (n = 343, 74%). The highest reason of visiting reported by the respondents was dispensing their prescription medications (n = 304, 65%) while purchasing medication without prescriptions was accounted with n = 162, (35%). The highest rate of the respondents was given advice about antibiotic use (n = 224, 48%) followed by physical exercises (n = 178, 39%) and healthy eating (n = 173, 37%). The majority of the respondents preferred to visit community pharmacy over other healthcare centers because of minor health problems (n = 358, 77%). The major factors influence the consumers choose any particular pharmacy were the professionalism of pharmacy staff (n = 254, 55%) and the availability of the medical products (n = 221, 48%). The respondents incline to choose community pharmacy as a primary health center when they faced drug related problem (n = 248, 54%). In conclusion, the current study revealed that the majority of Libyan people are regular users of community pharmacies and various services and topics of advice have been given by their staff. However, shortage of professional pharmacists in community pharmacies can undermine the opportunity of given reliable pharmaceutical care from these communications.

Mediterranean Journal of Pharmacy and Pharmaceutical Sciences Mediterranean journal of pharmacy and pharmaceutical sciences

Bioefficacy and persistency of insecticides against blister beetle, mylabris pustulata (thunb.) in pigeonpea, cajanus -cajan (l.) millsp

Blister beetle, Mylabris pustulata (Thunb.) is a polyphagous pest attacking flowers of pigeonpea (Cajanus cajan), cotton (Gossypium sp), lady’s finger (Abelmoschus esculentus), mungbean (Vigna radiata), urdbean (Vigna mungo), ricebean (Vigna umbellata) etc. throughout the country. Because of its polyphagous feeding nature and hard protective adaptation against insecticides, long term management of this pest with a single molecule is difficult. Therefore, field cum laboratory experiments were carried out for three consecutive cropping seasons during kharif 2008-09, 2009-10 and 2010-11 to find out the persistence and efficacy of different insecticides. It was found that decamethrin 2.8EC was 3334 times toxic with lowest LC50 value (0.0000563) followed by monocrotophos 36SL as compared with endosulfan which was the least toxic with LC50 value (0.1877). Insecticides evaluated for their persistent toxicity during 2009-10 revealed that decamethrin and thiodicarb caused cent per cent mortality of adult blister beetle immediately after spray. At 8th days after spraying, decamethrin caused 60 per cent mortality. Insecticides evaluated for their efficacy during the year 2010-11 revealed that the plants were found free from adult blister beetle population in treatments involving decamethrin and cypermethrin even at ten days after spray. Among all the treatments, spraying of thiodicarb 75WP @ 625 g ha-1 provided the highest grain yield (18.87 q ha-1). Maximum cost-benefit ratio was observed in monocrotophos 36SL, cypermethrin 25EC and decamethrin 2.8EC

DR. BABU LAL JAT Dr. babu lal jat

Phytochemical evaluation and pharmacological screening of didymocarpus pedicellata and ashwagandha for antiurolithiatic activity

The kidney stones are one of the most widely spreading disorders in the world. The present study was undertaken to evaluate the efficacy of ethanolic extract of Didymocarpuspedicellata and Ashwagandha for its antiurolithiatic activity in rats. Urolithiasis was induced in adult male albino wistar rats by 0.75% of ethylene glycol for 28 days. The effect of the oral administration of the ethanolicextracts has been studied and is compared with the effect of oral administration of Cystone(Himalaya) as a standard on Wistar rat. Ethylene glycol feeding resulted in hyperoxaluria as well as increased renal excretion of calciumand phosphate. Supplementation with ethanolic extract of the plants significantly reduced the elevated urinary oxalate, showing a regulatory action on endogenous oxalate synthesis. Both the plant extract showed significant antiurolithiatic activity

Zeenath Banu Zeenath banu

Utilization of information communication technology for the improvement of personnel economics in the administration of public secondary schools in rivers state

This study investigated utilization of information communication technology for the improvement of personnel economics in the administration of public secondary schools in Rivers state. The study had two objectives, with corresponding research questions and hypotheses. A descriptive survey design was employed, and the population consisted of 11,258 secondary school teachers from 258 public senior secondary schools in Rivers state, with 4,127 males and 7,131 females. A sample of 383 teachers (163 males and 220 females) was drawn from 15 public senior secondary schools using the Taro Yamane Formula and a two-stage sampling technique of stratified and simple random sampling. Data was collected using a self-structured questionnaire titled "Utilization of Information and Communication Technology and Personnel Economics in Secondary School Administration." The questionnaire underwent face and content validation by three experts and demonstrated good reliability with a Cronbach Alpha coefficient of 0.82. Research questions were answered using mean and standard deviation, while inferential statistics utilized the z-test. The findings indicated a significant difference between male and female teachers in their perceptions of ICT utilization for teachers' supervision and evaluation, highlighting the potential for ICT to improve personnel economics in the administration of public secondary schools in Rivers state. Based on these findings, it can be concluded that implementing various ICT-based strategies such as developmental supervision, contextual supervision, clinical supervision, and collaborative forms of developmental supervision could enhance the effectiveness of teaching staff and overall school productivity in public secondary schools in Rivers state.

FXintegrity Publishing Fxintegrity publishing

Influences of modern calculation tools and efficiency of insurance management in the global pandemic period

Object: The main purpose of the research is to develop modern tools for insurance management in the global economic crisis, to make an objective assessment based on a critical analysis of existing ones, to identify situations that could lead to international economic, social, and natural threats. It is made some recommendations for the development of insurance calculations for the republic of Uzbekistan. Methods: Methods for reforming modern calculation of insurance tariffication are recommended by means of theories of probabilities, statistical and mathematical analysis, and foreign advanced countries practical types of summarizing. Findings: While making an analysis, it has found that modern tools for the insurance management of Uzbekistan are needed. We proved this by the results of the modern calculation of insurance. For the development of the insurance market of Uzbekistan, it should be analyzed by means of penetration and density of insurance premiums, making the deepest calculation of risks of the economy of Uzbekistan, and using the main principles and formulas of the theory of probability. Conclusions: In the end, we can take some results, and give some recommendations such as using the tools of theories of probabilities can help us find the main risks of economy, it’s powers of influences of the market economy, statistical and mathematical analysis also add some practical, objective results for making under control of any types of insurance risks

Ikboljon Odashev Mashrabjonovich Ikboljon odashev mashrabjonovich

Impact of frontline demonstrations on chickpea (cicer arietinum) production, productivity and profitability in transitional plain of inland drainage zone of rajasthan

Pulses are well known richest source of vegetable protein and poor man’s food because of its essential component of diet. The frontline demonstrations of chickpea crop was carried out by Krishi Vigyan Kendra, Nagaur-I, Agriculture University, Jodhpur during rabi seasons from 2011-12 to 2019-20 on 178.5 ha area with 382 demonstrations in different clusters of Nagaur district of Rajasthan. The results shows that demonstrations produced on an average 18.02 q/ha grain yield of chickpea, which was 24.18 per cent higher as compared to prevailing farmers practice (14.51 q/ha). The front line demonstrations fetched more average gross returns (Rs.60161/ha), net return (Rs. 37963/ha) and B:C ratio (2.76) with slightly higher investment on cost of cultivation (Rs.1663/ha) as compared to farmers practice. The increase in gross and net returns was in the tune of Rs.11960 and Rs. 10285 per hectare with incremental benefit: cost ratio of 0.33. The average extension gap, technology gap and technology index was 350kg/ha, 608 kg/ha and 25.2 per cent, respectively. It is also observed that majority of the respondent farmers expressed high (51.83%) to the medium (32.72%) level of satisfaction regarding the performance of chickpea under demonstrations

DR. BABU LAL JAT Dr. babu lal jat

Review on the cardioprotective role of pinocemrin in atherosclerosis, myocardial infarction and related vascular-myocardial remodeling

Cardiovascular diseases represent a formidable global health challenge, standing as the foremost cause of both mortality and morbidity. Atherosclerosis and myocardial infarction, as primary contributors to this epidemiological burden, underscore the urgent need for effective therapeutic interventions with minimal side effects. Natural compounds derived from plants have emerged as promising candidates, given their enhanced efficacy and reduced adverse effects. Phytochemicals, in particular, have garnered attention for their potential as alternative therapeutic agents. This review delves into the cardioprotective potential of pinocembrin (5,7-Dihydroxy flavanone), a compound extracted from various plants and honey. Renowned for its antioxidant and anti-inflammatory properties, pinocembrin demonstrates significant cardioprotective effects through the modulation of diverse signaling pathways. Atherosclerosis and myocardial infarction entail intricate cellular mechanisms involving oxidative stress, inflammatory responses, cellular remodeling, and programmed cell death. Pinocembrin, by targeting key factors within these pathways, exhibits cardioprotective actions. While existing research underscores its effectiveness, further investigations are warranted to elucidate the impact of pinocembrin on additional cardiovascular conditions and explore novel molecular targets, thus paving the way for future advancements in therapeutic interventions.

Brinda Elangovan Brinda elangovan

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