Mediterranean Journal Of Pharmacy And Pharmaceutical Sciences
Phytochemical screening, antibacterial and anti-diabetic activities of moringa oleifera cultivated in east region of libya
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Moringa oleifera, a very important healthful plant, is one amongst the foremost wide cultivated species of the family Moringaceae. It's extremely valued from past as a result of its large healthful properties. Moringa oleifera, native to India, grows within the tropical and climatic zone regions of the globe. It's commonly called drumstick tree or horseradish tree. Moringa will face up to each severe drought and gentle frost conditions and, therefore wide, cultivated across the globe. With its high alimentary values, each part of the tree is appropriate for either nutritional or commercial purposes. The leaves are rich in minerals, vitamins and alternative essential phytochemicals. Extracts from the leaves are useful in treatment of anemia, enhance breast milk in wet mothers. It's used as a potential antioxidant, anti-cancer, anti-inflammatory, anti-diabetic and antimicrobial agent. Thus, this study was aim to investigate the phytoconstituents from ethanolic and aqueous extracts of the Moringa oleifera cultivated in Libya and to assess its anti-bacterial and anti-diabetics activity. The phytochemical investigations of these extracts of Moringa oleifera revealed the presence of alkaloids, carbohydrates, flavonoids, saponins, steroids, tannins and phenolic compounds. The antibacterial activity of cold and hot extraction of methanolic and water extracts of Moringa oleifera by using the well diffusion method were assessed. Results revealed that there was a profound antibacterial activity of the studied Moringa oleifera against representatives of Gram-positive bacteria. After in vitro evaluation of anti-hyperglycemic properties of the ethanolic extract of Moringa oleifera by testing its capacity to inhibit α-amylase activity, the methanolic extract exhibited inhibitory effect on the α-amylase enzyme.
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DOI : https://doi.org/10.5281/zenodo.5805927
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