Mediterranean Journal Of Pharmacy And Pharmaceutical Sciences

Effect of occupational exposure on hematological and biochemical parameters in workers at oil and gas companies

  • Authors Details :  
  • Ghada M. Salem,  
  • Seham Shaboun,  
  • Yosra M. Algamodei,  
  • Maram F. Almalyan,  
  • Ekhlass M. Althwadi,  
  • Ahmed A. Zaid,  
  • Sara A. Hwisa,  
  • Fakhri F. Aljidaemi,  
  • Salah A.b. Bahroun

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Petroleum refineries are largest chemical industries that are responsible for emission of several pollutants into the atmosphere. Benzene and its metabolites are regarded as the most hazardous compounds that are emitted by petroleum refineries. These contribute to toxic oxidants, which cause many serious health risks to petroleum refineries workers. This study was aimed to analyze the effects of chemical exposure on hematological and biochemical parameters among workers at Zawia oil refinery and Mellituh oil and gas refinery companies. A total of 200 workers participated in this study which consisting of two equal groups (each group: n = 100). The first group consists of petroleum refineries workers and the second group consists of non-oil work civil servants serving were recruited as exposed and control subjects, respectively. The results of blood picture, liver enzymes and kidney functions were compared between the groups. Mean white blood cells counts, platelet counts, and hematocrit count were significantly higher, while the mean red blood cells count was insignificantly changed in petroleum refineries workers. While the mean hemoglobin and corpuscular hemoglobin concentration levels were significantly lower, whereas the mean corpuscular volume and mean corpuscular hemoglobin levels were insignificantly changed in petrol refineries workers. Liver enzymes and renal functions were significantly higher in petrol refineries workers. The present findings indicate that occupational exposure to benzene causes significant alterations in hematological and biochemical parameters and workers are at high risk of developing blood, hepatic or renal related disorders. Protection and frequent medical attention should be given to petroleum refineries workers.

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DOI : https://doi.org/10.5281/zenodo.6399948

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