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Anti-inflammatory activity of luffa cylindrica

  • Authors Details :  
  • Kanwal Waseem,  
  • Muhammad Mohtasheemul Hasan ,  
  • Salman Ahmed,  
  • Syed Waseemuddin Ahmed,  
  • Iqbal Azhar

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The current study was designed to explore the anti-inflammatory effects of the crude hexane and ethanol extracts of the leaves and male flowers of Luffa cylindrica (L.) Roem., (sponge gourds) to validate its folk use. These extracts produced significant anti-inflammatory effects (p.o.) at doses of 500, 750 and 1000 mg/kg b.w. in carrageenin-induced paw oedema in rats compared to those obtained with indomethacin. The results of the present study provide evidence for the anti-inflammatory properties of the leaves and male flowers of Luffa cylindrica, which have potential therapeutic applications for inflammatory diseases.

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