India's hotel and hospitality industry occupancy decreased significantly in the first quarter of 2020, as the outbreak of COVID-19 affects different segments of the market. The outbreak of the novel coronavirus (COVID-19) has inflicted a blow on industries around the world, but maybe none as devastating as hospitality and travel. Depending on the length of the pandemic, companies across the industry adjusted growth forecasts for 2020, estimated profits to be conservatively 40-50 percent lower than expected before the outbreak. The effect on hospitality demand is greater than many other sectors, but even among hotels, air and cruise ships, and restaurants it is varied. Hotels and airlines operate at half capacity, with both business and leisure travelers canceling scheduled trips and not arranging any for the near future.The present article aims to study some novel practices for the survival of hospitality industries once the lockdown is over.

Ketan chande

The current study used the chick emesis model to explore the anti-emetic effect of the methanolic extract of Acalypha ornata Hochst—roots. Emesis was induced by the oral administration of copper sulfate to male chicks. Acalypha ornata root extract (150 mg/kg orally) showed an anti-emetic effect and was compared with the reference drug chlorpromazine

Dr. salman ahmed

Background: Avicenna, as the Persian physician, made a significant contribution to the field of medical sciences, especially surgery, in the 10th and 11th centuries AD. Methods: In the present paper, Avicenna's translated quoted words were shared about his surgical practice. Indexing databases of PubMed and Google Scholar were searched using keywords like Avicenna, surgery, and anesthesiology to find related papers and documents. Results: The first portion comprises some of the most commonly used simple and compound herbal preparations to produce general and local anaesthetics before the surgery and as dental anaesthetic agents. In the second portion, practices regarding surgical management for skull fractures, spinal trauma, bone fractures, cataracts, incurable urinary retention, bladder calculi, haemorrhoids, cancer, as well as endotracheal intubation and tracheostomy, have also been incorporated. Finally, it ends up with practices regarding the use of natural products as postoperative dressing for traumatic and surgical wounds and after cataract surgery. Conclusion: Based on the recent investigations, the findings of this review study will provide a brief insight into Avicenna’s Canon of Medicine and the sciences of anesthesiology and surgery.

Dr. salman ahmed

Prostate cancer (PCa) is the leading cause of cancer death in men, and its treatment is commonly associated with severe adverse effects. So, new treatment modalities are needed. In this context, natural compounds have been widely explored for their anti-PCa properties. Aquatic organisms contain numerous potential medications. Anticancer peptides are less toxic to normal cells and provide a productive treatment approach via multiple mechanisms, including altered cell viability, apoptosis, cell migration/invasion, suppression of angiogenesis and microtubule balance disturbances. This review sheds light on marine peptides as efficacious and safe therapeutic agents for PCa.

Dr. salman ahmed

ABSTRACT Objective: The objective of the present study was to develop an HPLC analytical method and to perform in vivo study of Emblica officinalis and Aegle marmelos extracts for antioxidant and antidiabetic activity. Methods: The phytochemical analyses, total phenolic content (TPC), TLC, DPPH assay were performed for freeze-dried Emblica officinalis fruits aqueous extract (EOFAE) and Aegle marmelos leaves ethyl acetate extract (AMLEAE). The active constituents present in both extracts were estimated by using HPLC system having Hibar® Results: Tannins, saponins, carbohydrate, glycosides are found in EOFAE; coumarins and flavonoids are found in AMLEAE and quinones, phenols are present in both extracts. The values of TPC present in standard gallic acid, EOFAE and AMLEAE were found to be 485.7, 315.6, 300.7 mgGAE/g, respectively. R C18 column [250 x4.6 mm, 5 µm] and UV detector (264 nm). A gradient mobile phase (acetonitrile and water with 0.1% trifluoroacetic acid) was used at a flow rate of 0.8 ml/min. In vivo antioxidant, antidiabetic activity of both extracts was conducted on male albino Wistar rats for 21 d in streptozotocin-induced diabetic rats (42 rats; n=6). The antidiabetic activity was measured by blood glucose level and biochemical parameters i.e. total cholesterol, triglycerides and total protein. Oxidative stress was measured by antioxidant biomarkers i.e. SOD, GSH, lipid peroxidation by thiobarbituric acid reactive substances method on the liver of the experimental rat. f Conclusion: The present study showed that the EOFAE and AMLEAE treated group III with (EOAM) low dose of 500 mg/kg body weight has potent antioxidant and antidiabetic activity. values obtained by TLC of EOFAE and AMLEAE were found to be 0.41 and 0.50, respectively. The values of % inhibition shown by EOFAE and AMLEAE in DPPH assay were found to be 97.8%±2 and 95.2%±2, respectively. The values of retention time of EOFAE and AMLEAE by HPLC analysis were found to be 4.59 and 5.28 min, respectively. Histopathological examination of the liver was revealed that low dose EOAM (containing of EOFAE 250+AMLEAE 250 mg/kg body weight) administered once a daily for 21 d showed significant activity (P˂0.001) with biochemical parameters and antioxidant biomarkers. Keywords: Emblica officinalis, Aegle marmelos, Antioxidant, Antidiabetic activity, streptozotocin, HPLC

Snehal

The current study was designed to explore the anti-inflammatory effects of the crude hexane and ethanol extracts of the leaves and male flowers of Luffa cylindrica (L.) Roem., (sponge gourds) to validate its folk use. These extracts produced significant anti-inflammatory effects (p.o.) at doses of 500, 750 and 1000 mg/kg b.w. in carrageenin-induced paw oedema in rats compared to those obtained with indomethacin. The results of the present study provide evidence for the anti-inflammatory properties of the leaves and male flowers of Luffa cylindrica, which have potential therapeutic applications for inflammatory diseases.

Dr. salman ahmed

Objective: Pyrazolopyrimidines are heterocyclic molecules containing nitrogen as the main composition, and hence, they exhibit pharmacological efficacy. They are analogs of purines so that possessing wide applications in the field of medicinal chemistry. The main objective of this study is to synthesize different derivatives of pyrazole-pyrimidine classes by adopting simple methodology as well as by employing green chemistry. The purpose of the synthesis of these molecules is to study the antitumor activity against Ehrlich ascites carcinoma (EAC) cell lines. Methods: After literature studies, it makes us to involve in the research of synthetic organic chemistry, especially to synthesize new compounds of pyrazolopyrimidines. We are reported solvent-free synthesis of pyrazolo [3,4-d]-pyrimidine-thiones through ethyl acetoacetate, hydrazine hydrate, thiourea, and different benzaldehydes. An ionic liquid 2-methyl-imidazolium-oxalate catalyzed the reactions under ultrasonication bath. Both conventional and ultrasonic methods were employed and comparison studies have been made. It was found that ultrasonic method completed the reaction quicker than the conventional method. All the synthesized compounds were confirmed their structures by 1 HNMR, Fourier transform infrared, 13C-NMR, and elemental analysis spectra. The compounds were tested for in vitro anticancer activity against EAC cell lines. Most compounds revealed significant anticancer activity relative to doxorubicin as a positive control with inhibitory concentration (IC50) values. Results: Ultrasonication method is a simple method under which all the reactions were completed at faster time (<7 min) compared to the convention method. Among eight molecules, 8a and 8d completed the reactions at a faster rate. We reported IC50 values of all the molecules, in which 8e and 8g were exhibited excellent potency against EAC cell lines at different concentrations .

Dr ganesh n yallappa

Teaching and learning computer programming is challenging for many undergraduate first-year computer science students. During introductory programming courses, novice programmers need to learn some basic algorithms, gain algorithmic thinking, improve their logical and problem-solving thinking skills, and learn data types, data structures, and the syntax of the chosen programming language. In literature, we can find various methods of teaching programming that can motivate students and reduce students’ cognitive load during the learning process of computer programming, e.g., using robotic kits, microcontrollers, microworld environments, virtual worlds, serious games, interactive animations, and visualizations. In this paper, we focus mainly on algorithm visualizations, especially on the different models of data structures that can be effectively used in educational visualizations. First, we show how a vector (one-dimensional array), a matrix (two-dimensional array), a singly linked list, and a graph can be represented by various models. Next, we also demonstrate some examples of interactive educational algorithm animations for teaching and learning elementary algorithms and some sorting algorithms, e.g., swapping two variables, summing elements of the array, mirroring the array, searching the minimum or maximum of the array, searching the index of minimum or maximum of the array, sorting elements of the array using simple exchange sort, bubblesort, insertion sort, minsort, maxsort, quicksort, or mergesort. Finally, in the last part of the paper, we summarize our experiences in teaching algorithmization and computer programming using algorithm animations and visualizations and draw some conclusions.

Ladislav végh

Improving the agricultural productivity is an imminent need to meet the food requirement of constantly growing population rate. It can be gracefully satisfied if the farming process is integrated through technologies such as big data and IoT. The integration of agricultural processes with modern technologies has emerged as the smart agriculture technology. This research work is focused on proving the suitability of the big data analytics for smart agricultural processes in terms of increasing production and quality of yields with less resources and overhead. This research paper expounds the extensive review carried out on the related works in smart agricultural farming, challenges in implementing the smart farming technologies at large scale, followed by the conceptual framework model for the effective implementation of big data together with IoT devices in smart farming.

Dr h shaheen

Background: Scabies is characterized by the presence of burrows, erythematous papules, and generalized pruritus which is usually worse at night. Recently an upsurge in the incidence of scabies has been reported in many settings, including the area of the study. The study aimed to determine if there is a nexus between scabies and climate change as a risk factor. Methods: This was a case-control study carried out in a Cottage Hospital. Case files of 18, 000 patients who attended the hospital between 2016 and 2019 were reviewed. The diagnosis was mainly clinical, i.e. based on the presence of itching in the typical scabies locations, presence of scabies burrows and history of similar itching in the other members of the patient’s household. 112 cases of scabies were diagnosed within this period. Results: From 2016 to 2019, the incidence of scabies rose from 3 to 50. Prevalence among males was 59.8%, and in females 40.2%, although the difference was not significant (p=0.0.53). Compared to other age groups, prevalence was highest in the 6-17 years age group (37.5%), but the difference among the age groups was also not significant (p=0.84). Conclusions: Within four years (2016-2019), the incidence of scabies had risen from 3 to 50 in the area of the study, being higher in males (59.8%) than females (40.2%), and in children less than 18 years (37.5%). Community survey, prompt diagnosis, adequate treatment and avoidance of overcrowding might help to stem the observed rising incidence of the disease.

Emmanuel umegbolu

Accounting is a fundamental aspect of business operations because it records transactions through which businesses achieve and retain profitability. Recoding transactions is an important aspect of business because the primary goal of businesses is to maximise profitability (Tirole, 2010). Accounting lays the groundwork to manage the income, expenses, assets and cash flow of the firm, all of which are pivotal to the financial health of the business regardless of its size. This report discusses different accounting principles in practice. The first task utilises the double-entry method to record the transactions of the business in ledgers using the double-entry method. This task also includes the formulation of a trial balance using the balance off rule and illustrates to which final account each trial balance entry is attributable. The second task involves the creation of final accounts for different businesses. The legal implications of varying business structures differ, so their financial statements are different. This task also includes a discussion of the properties, purposes, and structures of different financial statements. The third task addresses bank reconciliation. Bank reconciliation resolves any discordance between the records of the business and its bank statement. The gist of the fourth task is the use of control accounts. Control accounts summarise ledger balances to ensure a match between those accounts and the accounts in the ledger of each account.

Zamzam abdelazim

Strain improvement studies were conducted for the production of L-asparaginase from a marine fungus Beauveriabassiana SS18/14 by employing physical and chemical mutagens, in a systemic manner to obtain mutants that have higher L-asparaginase production. The wild strain produced 6.32 IU/mL of L-asparaginase activity while the UV mutant UVF-4 yielded 8.34 IU/mL and nitrous acid mutant UVF4-N-2 exhibited 10.44 IU/mL enzyme activity. The overall strain improvement programme increased L-asparaginase activity 1.65 times with respect to the parent wild strain.

Dr.p.v.kamala kumari

n India, the education sector has been always attentive to adopt innovations and techniques in the teaching-learning process due to various challenges. But nowadays, academic institutions are becoming flexible in accepting the new teaching and learning techniques to satisfy the student sector which as cited as the most vital entity in the educational sector. New technologies, tools, and techniques are proving as a boom for innovative teaching and learning practices. One of the emerging teaching technique is Blended learning which is a process refers to “mixing of the different learning environment for educational transfer”. It combines the traditional face to face classroom method with online learning method supported by advanced technology and tools. Blended learning should be viewed not only as a temporal construct but also as a fundamental redesign model. Through this content, delivery becomes digital and online. Truly blended learning requires teachers should adopt the approach as guides and mentors and learning should go beyond the classroom walls. Blended learning is also known as Hybrid learning. Although, Indian Government is taking initiatives to implement a blending learning approach yet there is a need to access the behavioral aspect of the students to use this blending learning approach. Adopting a blended learning approach must start with a re-examination of the intended learning outcomes.The deployment of cloud in the blended learning process makes its existence more strong. This study is the review of literature selected to identify the need for blended learning deploy with cloud in the teaching-learning process in the Higher Education Sector.

Inderbir kaur

In the name of Allah, Most Gracious, Most Merciful. Blessed be He in Whose hands is Dominion; and He over all things hath Power;- He Who created Death and Life, that He may try which of you is best in deed: and He is the Exalted in Might, Oft-Forgiving;- He Who created the seven heavens one above another: No want of proportion wilt thou see in the Creation of (Allah) Most Gracious. So turn thy vision again: seest thou any flaw? Again turn thy vision a second time: (thy) vision will come back to thee dull and discomfited, in a state worn out. And we have, (from of old), adorned the lowest heaven with Lamps, and We have made such (Lamps) (as) missiles to drive away the Evil Ones, and have prepared for them the Penalty of the Blazing Fire. For those who reject their Lord (and Cherisher) is the Penalty of Hell: and evil is (such), Destination. When they are cast therein, they will hear the (terrible) drawing in of its breath even as it blazes forth, Almost bursting with fury: Every time a Group is cast therein, its Keepers will ask, “Did no Warner come to you?” They will say: “Yes indeed; a Warner did come to us, but we rejected him and said, ´Allah never sent down any (Message): ye are nothing but an egregious delusion!´” They will further say: “Had we but listened or used our intelligence, we should not (now) be among the Companions of the Blazing Fire!” They will then confess their sins: but far will be (Forgiveness) from the Companions of the Blazing Fire! As for those who fear their Lord unseen, for them is Forgiveness and a great Reward. And whether ye hide your word or publish it, He certainly has (full) knowledge, of the secrets of (all) hearts. Should He not know,- He that created? and He is the One that understands the finest mysteries (and) is well-acquainted (with them). It is He Who has made the earth manageable for you, so traverse ye through its tracts and enjoy of the Sustenance which He furnishes: but unto Him is the Resurrection. Do ye feel secure that He Who is in heaven will not cause you to be swallowed up by the earth when it shakes (as in an earthquake)? Or do ye feel secure that He Who is in Heaven will not send against you a violent tornado (with showers of stones), so that ye shall know how (terrible) was My warning? But indeed men before them rejected (My warning): then how (terrible) was My rejection (of them)? Do they not observe the birds above them, spreading their wings and folding them in? None can uphold them except (Allah) Most Gracious: Truly (Allah) Most Gracious: Truly it is He that watches over all things. Nay, who is there that can help you, (even as) an army, besides (Allah) Most Merciful? In nothing but delusion are the Unbelievers. Or who is there that can provide you with Sustenance if He were to withhold His provision? Nay, they obstinately persist in insolent impiety and flight (from the Truth). Is then one who walks headlong, with his face grovelling, better guided,- or one who walks evenly on a Straight Way? Say: “It is He Who has created you (and made you grow), and made for you the faculties of hearing, seeing, feeling and understanding: little thanks it is ye give. Say: “It is He Who has multiplied you through the earth, and to Him shall ye be gathered together.” They ask: When will this promise be (fulfilled)? – If ye are telling the truth. Say: “As to the knowledge of the time, it is with Allah alone: I am (sent) only to warn plainly in public.” At length, when they see it close at hand, grieved will be the faces of the Unbelievers, and it will be said (to them): “This is (the promise fulfilled), which ye were calling for!” Say: “See ye?- If Allah were to destroy me, and those with me, or if He bestows His Mercy on us,- yet who can deliver the Unbelievers from a grievous Penalty?” Say: “He is (Allah) Most Gracious: We have believed in Him, and on Him have we put our trust: So, soon will ye know which (of us) it is that is in manifest error.” Say: See ye?- If your stream be some morning lost (in the underground earth), who then can supply you with clear-flowing water?

Kamal singh

Vigna unguiculata (L.) Walp. (Papilionaceae) is a medicinally important plant and is used for the treatment of different diseases. Alkaloids, phenols, flavonoids, and phytic acid have been reported in this plant. Antioxidant, antidiabetic and hypocholesterolemic activities are reported by Vigna unguiculata. The present review attempts to compile all the previous data based on its medicinal uses, phytochemistry and pharmacology reported in the earlier articles.

Dr. salman ahmed

Every religion includes a whole series of beliefs and practices and we should start by concentrating our attention on religious practices to understand a religion. This paper intended to clarify the religious practices of Vietnamese Catholic Youth. Based on the theory of Glock and Stark and by using survey method, descriptive statistics, this is the first study to demonstrate the religious practices of youths in a diocese of Vietnam. This issue considered as an interesting research topic in the context of Vietnamese research because it explores youths lives from a different perspective by focusing on the micro level of analysis. The respondents in this study were total of 388 young adults between 18 and 30 years of ages from 24 parishes who were randomly selected through Probability Proportional to size sampling method. The findings of the research indicate that the ritualistic dimension of religiosity among Vietnamese Catholic youth is still so high in the context of change in Vietnam

Le minh tien

The coronaviruses are group of viruses containing about seven members that have genetic material of RNA. They are surrounded by the protein capsid and lipid-containing membrane which has spike protein as flower petals. This family of viruses can infect animals and birds as well as humans causing signs and symptoms of respiratory system. However, these depend on the immune system of the infected host. The COVID-19 pandemic is a major global health disaster and the greatest task have faced the world. The infecting agent of COVID-19 disease was identified on December 31st, 2019 by Chinese scientist in Wuhan City. It was named Novel Coronavirus (Severe Acute Respiratory Syndrome-2 or SARS-2). After that, health minister of China announced that this virus is a new Coronavirus and it is of very high contagious rate [1]. In spite of the existence of many infectious cases in Libya at the winter season, the National Center of Disease Control (NCDC) announced about the first case of coronavirus on March 24th, 2020. It was identified by using a RT-PCR technique for a patient who came from Saudi Arabia. The NCDC, which is the government corporation responsible for the COVID-19 in Libya, has a daily news report about COVID-19 situation, including numbers of new cases infected patients, healing cases and total deaths number all over the country

Mediterranean journal of pharmacy and pharmaceutical sciences

Here is presented a short review on the medical potency of the most toxic plant of Europe. In many countries it isn't concerned any more as therapeutic agent in medicine due to frequent intoxications. However, in the homeopathy, preparations and patent medicines still contain aconitine and other alkaloids (abundant levels). There exists even a US Patent "ACONITINE COMPOUNDS, COMPOSITIONS, USES, AND PREPARATION THEREOF" (No. US 9,085,536 B2 by du Bois et al. 2015).

Stefan dahl

This paper addresses global supply chain management (GSCM). The industry used to explore this topic is the automotive industry, as it is a core industry in the world economy, both in revenue generation and inefficiency. The paper explores both the positive and negative attributes of supply chain management, explores and analyses the gap between evaluation and implementation of improvements in supply chain management and then looks into the global issues affecting supply chain management and their solution.

Mohamed sorogy

Prevalence of hypovitaminosis D is not restricted to the elderly and hospitalized population. Worldwide, the rate of prevalence of vitamin D deficiency has grown up rapidly in adults over the past decades. Among Libyan population including young students may has a high risk of vitamin D deficiency. The aims of this study were to examine vitamin D status among pharmacy students of Sebha University and to study the hematological profile as well as correlation of vitamin D deficiency with incidence of anemia among the students. This study was carried out on Pharmacy students from 13th January to 12th March, 2020. This is a cross-sectional study designed to determine vitamin D status among healthy young pharmacy students studying at the Sebha University. The blood samples were collected randomly from 62 pharmacy students to analysis complete blood count and 25-hydroxyvitamin D. The concentration of hemoglobin on total student was 12.5 ± 1.9 g/dl which was normal according to the WHO level (12.0 g/dl). Out of total, 36 students (59.1%) were found to have normal hemoglobin concentration (13.7 ± 1.4 g/dl) and 26 students (40.9 %) were found to have low hemoglobin concentration (10.8 ± 1.1 g/dl). Other blood profile as HCT, MCV, MHC and MCHC where statistically significant lower but the counts of RBCs, WBC and platelets were not on anemic group comparing to normal group. The present study reported that majority of pharmacy students in male and female blood donors have low vitamin D levels which represent (87.0%). Out of the total participants (n = 54) who have low vitamin D (n = 49, 79.0%) were classified under vitamin D deficiency category while (n = 05, 08.0%) of students had vitamin D insufficiency. In conclusion, prevalence of hypovitaminosis D (low 25-hydroxyvitamin D) among the pharmacy students at Sebha University was highly occurrence with concomitant a high rate of prevalence of anemia. Thus, vitamin D deficiency at this age represents a public health problem that should be addressed.

Mediterranean journal of pharmacy and pharmaceutical sciences