Molecular characterization of melanin pigment producing actinomycetes.

The soil samples were collected from Melia dubia plantations in two different locations in Tamil Nadu. A total of twenty five actinomycetes isolates were isolated and they were screened for melanin pigment production using different culture media. Only two isolates were able to produce melanin pigment under in vitro study and one isolate showed positive reaction to L-tyrosine substrate. Based on morphological and bio-chemical characters the isolate was identified as Streptomyces sp. The DNA of the isolate was isolated and its 16S rDNA gene was amplified and sequenced. The phylogenetic analysis of Streptomyces puniciscabiei was carried out.

Dr. SARANYA DEVI K Dr. saranya devi k

Insecticidal activity of castanospermum australe against stored grain pest callosobruchus analis

The butanol fraction of the leaves of Castanospermum australe Cunn. & Fraser., was tested on adult Callosobruchus analis (pulse beetle) for its insecticidal activity by impregnation method at concentrations of 3, 9, 48, 240 and 354 μg / cm2. The result showed that the extract is toxic to Callosobruchus analis and the LD50 was found to be 38 µg/cm2. The insecticidal activity of the butanol fraction of Castanospermum australe leaves against adult Callosobruchus analis was determined by impregnation method in five different concentrations and the result so obtained revealed that the extract is toxic against the test insect (pulse beetle). The mortality was lowest (14 %) at 3 µg/cm2 and highest (96 %) at 354 µg/cm2 (Table). The LD50 by log-log graph was found to be 38 µg/cm2. It may be said that the saponins of this plant could be utilized as a natural insecticide that could be an effective alternative for insect pest management.

Dr. Salman Ahmed Dr. salman ahmed

Implementasi strategi cooperative learning tipe jigsaw dalam pembelajaran akidah akhlak kelas v min bangka belitung pontianak

Penelitian ini dilatar belakangi oleh adanya permasalahan yang terjadi pada MIN Bangka Belitung Pontianak seperti guru kurang melibatkan siswa dalam materi pembelajaran, guru cenderung menyampaikan materi dengan menggunakan metode ceramah tanpa adanya variasi sehingga menyebabkan kejenuhan dalam belajar, guru kurang memahami dalam tentang memilih dan menentukan strategi cooperative learning tife jigsawyang tepat sehingga berdampak pada terciptanya proses pembelajara yang lebih baik. Penelitian bertujuan untukmengetahui: perencanaan, langkah-langkah, dan evaluasi dalam pembelajaran Materi Aqidah dengan Strategi Cooperative Tipe Jigsaw dalam pembelajaran Akidah Akhlak Materi Sikap pada guru di Kelas V MIN Bangka Belitung Pontianak Tahun Pelajaran 2017/2018. Hasil penelitian ini dapat disimpulkan bahwa Perencanaan Strategi Cooperative Learning Tipe Jigsawdalam Pembelajaran Akidah Akhlak Pada Materi Akhlak Tercela di Kelas V MIN Bangka Belitung Pontianak dengan lebih baik dan siswa lebih aktif dalam proses pembelajaran; langkah-langkah strategi cooperative learning tipe jigsaw dalam materi sikap siswa di sekolahdi kelas V MIN dibagi menjadi 5 kelompok, setiap kelompok diksih materi pembelajaran, dan siswa mendiskusikan dengan materi tersebut; Pelaksanaan evaluasi proses dan hasil kegiatan pembelajaran yang menggunakan langkah strategi cooperative learning tipe jigsaw dalam materi sikap siswa di sekolahdi kelas V MIN Negeri Bangka Belitung Pontianak adalah menggunakan tes tertulis dan tes lisan juga mengunakan penilain proses dari observasi siswa saat proses pembelajaran atau setelah mata kuliah selesai.

EDUCARE: Journal of Primary Education Educare: journal of primary education

Exploring globally used antiurolithiatic plants of m to r families: including myrtaceae, phyllanthaceae, piperaceae,polygonaceae, rubiaceae and rutaceae

Urolithiasis is a common worldwide problem with high recurrence. This review covers thirty-six (36) families starting from alphabet M to R. It includes Rubiaceae (17); Phyllanthaceae and Rutaceae (09); Polygonaceae (08); Pinaceae and Piperaceae (06); Menispermaceae, Myrtaceae, Oleaceae, Oxalidaceae, Plantaginaceae and Ranunculaceae (05); Moraceae and Musaceae (04); Meliaceae, Orchidaceae and Rhamnaceae (03); Moringaceae, Onagraceae, Papaveraceae, Pedaliaceae, and Polygalaceae (02); Magnoliaceae, Malpighiaceae, Molluginaceae, Myoporaceae, Nyctaginaceae, Paeoniaceae, Parmeliaceae, Parnassiaceae, Periplocaceae, Platanaceae, Polypodiaceae, Portulacaceae, Primulaceae and Punicaceae (01) plant used globally in different countries. Hopefully, this review will be helpful for the general public and attract the scientific world for antiurolithiatic drug discovery.

Dr. Salman Ahmed Dr. salman ahmed

Assess the premenstrual symptoms and coping strategies among adolescent girls

Menstruation is a normal physiological impact on each girl’s life. Menstruation is monthly uterine bleeding for 3-5 days after every 28 days from puberty till menopause. A change in mood, behaviour, appearance of some abnormal vague symptoms is often noticed in the second half of the cycle. Symptoms are severe enough to disturb the life cycle of a woman called premenstrual syndrome (PMS). The study aimed to assess the premenstrual symptoms and coping strategies among adolescent girls. The majority of the students suffered from premenstrual syndrome. Objective: to assess the premenstrual symptoms and coping strategies among adolescent girls. Methodology: A nonexperimental descriptive research design was adopted in this study. Non probability convenient sampling technique was used to select the sample size of 30 adolescent girls. The assessment of premenstrual symptoms and coping strategies was carried out using a self-reported Likert’s rating scale. Data was analyzed by using descriptive and inferential statistics. Result: Majority (93.3%) of the samples sometimes had physiological and psychological problems, 90% of them had behavioural symptoms. Majority (43.3%) of the samples always followed coping strategies and 16.7% of the samples sometimes followed coping strategies and 40% never followed any coping strategies. Conclusion: PMS was common among students at 18-24 years. The most common physical symptoms experienced by adolescent girls were headache, backache and lower abdominal pain. Adolescent girls used coping strategies as taking hot / cold drinks, do not express anger to others, and turn to study and forget things, hearing music and taking medications. Keywords: Premenstrual Symptoms, physiological, psychological & behavioural symptoms, Coping Strategies, Adolescent Girls.

Elsi Queen Elsi queen

A review on image segmentation

Along with computer technology, the demand of digital image processing is too high and it is used massively in every sector like organization, business, medical etc. Image segmentation enables us to analyze any given image in order to extract information from the image. There are numerous algorithm and techniques have been industrialized in the field of image segmentation. Segmentation has become one of the prominent tasks in machine vision. Machine vision enables the machine to vision the real world problems like human does and also act accordingly to solve the problem so it is utmost important to come up with the techniques that can be applied for the image segmentations. Invention of modern segmentation methods like instance, semantic and panoptic segmentation have advances the concept of machine vision. This paper focuses on the various methods of image segmentation along with its advantages and disadvantages.

Manoj Kumar Pandey Manoj kumar pandey

Challenges experienced by students at stellenbosch university that hinder their ability successfully to learn online during the covid-19 era: a demographic and spatial analysis

The purpose of this meta-methods study (i.e., involving the full[er] integration of multiple methods research approaches and mixed methods research approaches) was to examine challenges experienced by students at Stellenbosch University that hinder their ability successfully to learn online during the emergency remote teaching that began in April 2020 due to the COVID-19 pandemic. Specifically, 1,932 students completed an online questionnaire. Analyses of the open-ended responses via WordStat 8.0.29 topic modeling (i.e., crossover mixed analysis) led to the identification of seven (challenge) themes that categorised the students’ challenges. In turn, via a principal component analysis of the themes (i.e., crossover mixed analysis), these seven themes were collapsed into four dimensions (i.e., meta-themes). A latent class analysis (i.e., qualitizing) yielded seven profiles of students. Disaggregating the themes by demographic and location variables led to the identification of subgroups who are most at risk for experiencing each challenge type. Implications of these and other findings are discussed.

Dr Emmanuel Ojo Dr emmanuel ojo

The effect of lockdown due to covid-19 on mentally ill patients and their caregivers: a cross sectional study

Background: Pandemics are known to cause poor mental well-being and an increased risk of mental disorders. The foremost concern emerging from different aspects of COVID-19 is its impact on mental health. There were many surveys conducted on the general population related to the effect of COVID-19 and few studies on its psychological impact but there is sparse literature on how the containment measures affected the psychiatric patients. Objective of the study was to investigate whether the COVID-19 related lockdown affected the subjective mood and behavior of psychiatric patients and their caregivers. The secondary purpose is to assess the difficulties encountered in procuring medicines and the effect of non-availability of homoeopathic medicines if any. Methods: A cross-sectional survey was conducted on mentally ill patients and their care-givers in the Outpatient Department of Psychiatry in National Homoeopathy Research Institute in Mental Health (NHRIMH), Kottayam. Respondents were evaluated with a specially framed questionnaire containing 22 questions to assess the effect of lockdown on psychiatric patients and their caregivers, who attended the OPD after the COVID-19 related lockdown. The data generated through the study are analysed and presented in this article. Results: Out of the total 548 participants (M-65.9%, F-34.1%) who responded to the survey, 290 (53%) cases expressed that they were distressed to be under lockdown. 26.5% of the clients reported worsening of mental health conditions during lockdown compared to pre-lockdown. 54.2% of the patients found difficulty in procuring homoeopathic medicines during Lockdown. Conclusions: Authorities should consider the ways of limiting the effects of confinement on mentally ill patients and their caregivers by developing strategies to mitigate the adverse consequence of the pandemic.

Dr deepthi gilla

Molecular changes in invasive front of oral cancer

Treatment planning for oral squamous cell carcinoma (OSCC) is based on the clinical TNM (Tumor, Node and Metastasis) classification. This system operates on the assumption that small tumours without clinical spread have a better prognosis than larger tumours with metastases. However, it is a well-known fact that some tumours with the same clinical staging show different growth patterns and clinical behaviour. This makes the prognosis for patients with OSCC difficult to predict on the basis of clinical staging alone. Although many histopathological characteristics of OSCC have been identified as prognostic factors, none is believed to be completely infallible. Therefore, a great need exists for more reliable prognostic markers, which will assist in treatment decisions. It is now well documented that several molecular events of significance for tumour spread, such as gain and loss of adhesion molecules, secretion of proteolytic enzymes, increased cell proliferation and initiation of angiogenesis occur at the tumour–host interface or invasive front, where the deepest and presumably most aggressive cells reside. This review describes the various molecular events and interactions, which take place in the invasive front of the OSCC, and elucidates their role as prognostic markers.

Mohit Sharma Mohit sharma

Prevalence of hypothyroidism among libyan pregnant women in benghazi

Hypothyroidism is a common endocrine disorder resulting from deficiency of thyroid hormone or its effects on peripheral tissues. Previous hospital based study have revealed high prevalence of hypothyroidism in pregnant women. Also, studies with small sample size indicated a rising trend of prevalence of hypothyroidism during pregnancy. Moreover, pregnancy is seen as a risk factor in the occurrence of thyroid dysfunctions. Thus, the aim of was to assess and analyze prevalence of hypothyroidism among Libyan pregnant women in Benghazi city in to study its relation and risk in pregnancy. The study was conducted on a sample size of 177 Libyan pregnant women in Benghazi city in Libya during 2018. A cross-sectional observational study was conducted in clinics located in Benghazi city. Responses to the question was coded and analyzed. The prevalence of hypothyroidism among the pregnant women was found to be 10.2% (n = 18) and no significant relation between age and hypothyroidism among women. Only nine percent of the pregnant women had medical conditions (as diabetes mellitus and high blood pressure). 28% of the hypothyroidism pregnant women are of the first gestation and 72% are of the second or more. 83% of the hypothyroidism pregnant women had no thyroidectomy. Thus, this study concludes that there is a high prevalence of hypothyroidism during pregnancy period in Benghazi and a national screening is necessary for hypothyroidism in Libya.

Mediterranean Journal of Pharmacy and Pharmaceutical Sciences Mediterranean journal of pharmacy and pharmaceutical sciences

The perspective of covid-19 vaccines

The current COVID-19 is now endemic on everycontinent and becomes the most challenging outbreaks over centuries, thus millions of people have been infected with the novel coronavirus (SARS-CoV-2), and have contributed to the deaths of more than two millionpeople. Researchers are working continuously to develop safe and effective vaccines that people have started receiving since December 2020. Vaccines against severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) are the most important countermeasure to the COVID-19 pandemic taking into considerationthat vaccines induce a robust immune response

Mediterranean Journal of Pharmacy and Pharmaceutical Sciences Mediterranean journal of pharmacy and pharmaceutical sciences

Growth of urate (gouty and urinary) crystals on glass slide: a simple and inexpensive in vitro model to evaluate natural antiurolithiatic and anti-gout drugs

Noncommunicable diseases, also known as chronic diseases, tend to last long and result from genetic, physiological, environmental, and behavioural factors. Uric acid nephrolithiasis, arthritis and gout come under noncommunicable diseases related with Monosodium urate monohydrate (MSUM ) crystals. MSUM crystals are deposited in peripheral joints, causing gout and eliciting an intense localized inflammatory attack. In contrast, in collecting ducts and medullary interstitium, it is a urinary calculi which causes dysuria, nausea and hematuria. The study aims to explore the possible morphological features of monosodium urate monohydrate crystals. The study was carried out on a glass slide under a microscope to observe the growth patterns of MSUM crystals. For this purpose, a drop of gel medium (sodium meta silicate solution + 0.2M sodium hydroxide + 2N acetic acid) at pH 5.02 - 5.17 was placed in the middle of a glass slide and converted into a gel. A 0.07 M uric acid drop was added to the adequately formed gel. The glass slide was observed under a microscope till it was completely dried. Monosodium urate monohydrate was formed as spherical ring banded spherulites, dumbbell and composite spherulites. The current study provides different phases of MSUM crystallization on a glass slide for the first time. It may also be used as a model to evaluate prophylactic management against gouty and renal stones through in vitro assessment of crystal growth and aggregation inhibition and modulation of developing or developed crystals by using different natural products.

Dr. Salman Ahmed Dr. salman ahmed

Role of diaphragmatic breathing exercise in the rehabilitation of chronic low back ache

A 55‑year‑old male patient who has undergone physiotherapy sessions on and off for about 6 months has been admitted to the hospital for the recurrence of back pain along with it he has slight breathing issues while performing day‑to‑day activities, especially in forward bending activity and has been treated with pain killers and muscle relaxants during the medication periods. The patient is feeling better again, but his symptoms continue to worsen. Later, he was referred to a pulmonologist for additional evaluation after presenting with decreased diaphragm excursion, which was causing a disordered breathing pattern. He was treated with medication and referred to additional rehabilitation for low back pain management after a thorough physical examination that also included checking the patient's core and deep breathing muscles Activities of Daily Living (ADL) activities. Keywords: Chronic low back ache, diaphragm excursion and lumbar mobility, diaphragmatic breathing exercise

Nagaraj sibbala Nagaraj sibbala

Ai-based predictive analytics for proactive care

This article explores the intersection of Artificial Intelligence (AI) and predictive analytics in healthcare, focusing on the transformative role of AI-based predictive analytics in enabling proactive and personalized patient care. Through an in-depth analysis of recent advancements, practical implementations, and ethical considerations, the paper elucidates how these technologies contribute to early intervention, improved patient outcomes, and enhanced healthcare efficiency.

Dhruvitkumar Talati Dhruvitkumar talati

Effective key management in dynamic wsn

Recently, wireless sensor networks (WSNs) have been deployed for a wide variety of applications, including military sensing and tracking, patient status monitoring, traffic flow monitoring, where sensory devices often move between different locations. Securing data and communications requires suitable encryption key protocols. In this paper, we propose a certificateless-effective key management (CL-EKM) protocol for secure communication in dynamic WSNs characterized by node mobility. The CL-EKM supports efficient key updates when a node leaves or joins a cluster and ensures forward and backward key secrecy. The protocol also supports efficient key revocation for compromised nodes and minimizes the impact of a node compromise on the security of other communication links. A security analysis of our scheme shows that our protocol is effective in defending against various attacks.We implement CL-EKM in Contiki OS and simulate it using Cooja simulator to assess its time, energy, communication, and memory performance.

Dr H Shaheen Dr h shaheen

دراسة تأثیر ألمیثیونین المضاف إلى كسبة فول الصویا بدیلا عن المركز البروتیني في علائق فروج اللحم البادئة في بعض الصفات الإنتاجیة

This Experiment was conducted on 120 day old unsexed Ross broiler chicks to study the effect of added methionine to soybean meal as substitute for protein concentrate in the starter ration on some productive traits . The chicks were raised on floor were distributed to three treatments with four replicates each ( 10 birds) . The three experimental starter rations (1-28) day contained 2800 kcal/kg ME and 22% cp . The first supplemented with 5% protein concentrate , while the second and third were with out protein concentrate but supplemented with 0.1 and 0.2% methionine respectively . The Finisher ration (29-49) day contained 3047 kcal/kg ME and 19.19% cp. At 49 day of age 2 birds from each replicate were slaughtered for carcass traits . Statistic analysis of data showed a significant increase (P ≤ 0.05) in body weight , weight gain , feed and protein efficiency ratio for third treatment during (1-28) day , No significant difference in all studied traits during (29-49)day, and the third treatment showed best economic efficiency .

RAFEA MOHAMMEDTAHER KHULEL Rafea mohammedtaher khulel

Formulation design and evaluation of mucoadhesive buccal patch of ketorolac for the treatment of periodontitis

Ketorolac tromethamine, the non-steroidal anti-inflammatory drug, was formulated into mucoadhesive films to overcome the limitations in the currently available dosage and routes of administration which in sequence will increase patients’ compliance. Films were cast from organic and aqueous solvents using various bioadhesive polymers namely: HPMC E-15, Eudragit RLPO, Eudragit RSPO, Carbopol 934P. The prepared films were subjected to investigation for their physical and mechanical properties, swelling behaviors, in vitro bioadhesion, drug permeation via bovine buccal mucosa, and in vitro drug release. These properties were found to vary significantly depending on the preparation methods, the type of the polymers, and the ratio of addition of both plasticizers (i.e. polyethylene glycol and film forming agent. Formulation F4 is selected for best formulation because it shows the 98.85% drug release at time 6 hr. In addition, this film was subjected to in vitro and in vivo release. The obtained results indicate that the concentration of ketorolac in the oral cavity was maintained above 4.0 µg/ml for a period of at least 6 h. This film shows promising results for using the ketorolac mucoadhesive route of administration topically and systemically, and thus it will be subjected to clinical evaluation in future work.

Kuldeep vinchurkar

Wto, and its impact on higher education in global contxt

The cross line movement according to the two labor and products is the thing to take care of in the present worldwide economy. Worldwide exchange labor and products has for some time been a standard, for different advantages that gather from it. There have been numerous respective and multilateral arrangements comparable to cross line exchange dealings. The development of administrations area that decidedly influences the everyday daily routine and guidelines of experiencing or personal satisfaction. The World Trade Organization (WTO), of which in excess of 156 nations are individuals, has an understanding according to global administrations exchange. The General Agreement on Trade in Services (GATS) is the WTO's arrangement that administers exchange 12 sorts of administrations, including 'instruction administrations.Each WTO part that proposes to change its 'advanced education administrations' area to outline the 'responsibilities' by specifying certain conditions or restrictions with respect to its strategy on such progression. Contingent upon certain public or provincial targets and the states of interest and supply of advanced education, every part would set down various types of conditions while changing the area to unfamiliar instructive foundations. One of the basic inquiries or issues in such manner would be corresponding to the sort of college to be permitted to set up its grounds or branch or in any case offer training administrations. The inquiry raised here is should WTO individuals from Pro training Services Liberalization permit Foreign Private Universities or Foreign Public Universities?

Dr Gedam Kamalakar Dr gedam kamalakar

De la rhétorique du politiquement correct dans le discours présidentiel algerien: éléments d’analyse discursive

Le discours du nouveau Président algérien, Monsieur Abdelmadjid Tebboune, se caractérise par une rhétorique différente de celle de ses prédécesseurs. Notre entreprise, dans le présent article, vise à rendre compte de cette spécificité discursive en interrogeant trois expressions ponctuant souvent son discours. Notre analyse se propose d’examiner des segments de discours collationnés à partir des différents entretiens périodiques accordés aux médias nationaux et internationaux ainsi que des allocutions du président lors des travaux réunissant le gouvernement et les walis. En guise de conclusion, nous déterminerons les motivations du choix de ces formules dans le discours présidentiel.

Assanvo

A comprehensive glimpse on globally used antiurolithiatic plants of convolvulaceae, costaceae, ebenaceae, fagaceae, hypericaceae, lauraceae, liliaceae and lythraceae

Urolithiasis is a common worldwide problem with high recurrence. This review covers Convolvulaceae seven (07), Costaceae four (04), Ebenaceae four (04), Fagaceae six (06), Hypericaceae eight (08), Lauraceae nine (09), Liliaceae twelve (12) and Lythraceae three (03) plants used globally in different countries. Hopefully, this review will be helpful for the general public and attract the scientific world for antiurolithiatic drug discovery.

Dr. Salman Ahmed Dr. salman ahmed

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