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Chapter 4.23 - vitamin e (tocopherols and tocotrienols) (natural-occurring antioxidant; bright and dark side). in: antioxidants effects in health. edited by seyed mohammad nabavi and ana sanches silva

  • Authors Details :  
  • Ziyad Khan,  
  • Salman Ahmed,  
  • Marya,  
  • Hammad Ullah,  
  • Haroon Khan

Journal title : Antioxidants Effects in Health

Publisher : Elsevier

Page Number : 547-560

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Vitamin E is extensively available in the natural world and is produced by prototrophs such as plants, algae, and blue-green algae. Vitamin E is used as a dietary supplement, an antioxidant food stabilizer, a pharmaceutical additive, and a preservative in livestock feed. Several types of vitamin E can be differentiated by the position and number of the methyl functional group, and each form has a unique biological role. The function of antioxidants such as vitamin E is to defend cells from the effects of oxidative stress. Vitamin E is a free radical scavenger converted to vitamin E radical, then converted back to vitamin E by ascorbic acid. Vitamin E was discovered by Evans and Bishop in 1922; it has proved to be an effective nutrient for reproduction. It is also possible for vitamin E to act by a mechanism not directly linked to the inhibition of oxidation. Such non-antioxidant actions of vitamin E may result from gene regulation and specific cell signalling. The function of vitamin E in cellular signalling, especially its biological impact, is undoubtedly an imperative subject for future studies. The explicit roles of the several isomers and esters of vitamin E analogues should also be the subjects of future studies.

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DOI : https://doi.org/10.1016/B978-0-12-819096-8.00066-5

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