Dr. Salman Ahmed

Toxicity assessment of mucuna pruriens linn seeds

  • Authors Details :  
  • Salman Ahmed ,  
  • Burhan Qureshi,  
  • Muhammad Mohtasheemul Hasan,  
  • Syed Waseemuddin Ahmed,  
  • Iqbal Azhar

648 Views Research reports

Plants have been used as medicine for the treatment of diseases for thousands of years. These herbal remedies, although natural, can cause some serious damaging effects on the vital organs of the body due to inadequacy in standardization and safety regulations. Mucuna pruriens Linn. belongs to the family Fabaceae and is used traditionally in various ailments. The present study reports the acute systematic toxicity and topical toxicity of methanolic extract of Mucuna pruriens (seeds) on albino mice and rabbits respectively. The test solution was injected intravenously into the tail as 1ml/20gm of the mice body weight. The observation was made immediately and after 1/2, 1, 4, 24, 48 and 72hours of drug administration. Mice showed normal activity till 72hours. The intracutaneous test is designed to evaluate local responses to the extracts of materials under test following intracutaneous injection into rabbits. The toxicological investigations of Mucuna pruriens with particular reference to intracutaneous toxicity in experimental animals displayed that it showed slight edema.

Article QR Code

Toxicity assessment of mucuna pruriens linn seeds QR Code

Article Subject Details




Article File

Full Text PDF





More Article by Dr. Salman Ahmed

Analgesic and antiemetic activity of cleome viscosa l.

The seeds of cleome viscosa are used in traditional systems of medicine for the treatment of many diseases in asia. this study evaluated fixed oil from the seeds of cleome viscosa...

Antiemetic activity of some aromatic plants

The current study was conducted to explore the antiemetic activity of ten aromatic medicinal plants viz., carissa carandus l. (fruits), chichorium intybus l (flowers), cinnamum tam...

Anti-emetic activity of some leguminous plants

Crude methanol extracts of the leaves of adenanthera pavonina l., peltoforum roxburghii l, prosopis cineraria l., and prosopis juliflora dc., were evaluated for anti-emetic activit...

Acute systemic toxicity of four mimosaceous plants leaves in mice

Nature provides drugs in the form of medicinal plants to cure all ailments of mankind with fewer side effects. these medicinal plants can cause some serious damaging effects on th...