Tidal and riverine flows are viable energy sources for consistent energy production. Installing and operating marine hydrokinetic (MHK) turbines requires assessing any potential impact of debris accumulation on turbine performance and sediment transport. More specifically, MHK devices may alter the natural sediment transport processes and cause debris accumulation, disrupting the natural sediment dynamic. In turn, these processes could affect the turbine’s performance. We carried out a series of large-eddy simulations coupled with bed morphodynamics, introducing various debris loads lodged on the upstream face of a utility-scale turbine tower. The objective is to systematically investigate the impact of debris accumulation on the performance and hydro-and morpho-dynamics interactions of the horizontal-axis MHK turbine under rigid and mobile bed conditions. To that end, we (1) employed the actuator line and surface methods for modeling turbine blades and the nacelle, respectively,(2) directly resolved individual logs, and (3) solved the Exner equation to obtain the instantaneous bed deformation of the mobile bed. Our analysis revealed that while the spinning rotor amplifies scour around the pile, debris accumulation modifies the sediment dynamics of the system. Also, it found that morphodynamic processes accelerate the wake recovery, slightly enhancing the turbine's performance.

Hossein seyedzadeh

Purpose: Congenital hypogonadotropic hypogonadism (CHH) is a rare genetic disorder mostly characterized by gonadotropins release and/or action deficiencies. Both isolated (idiopathic hypogonadotropic hypogonadism) and syndromic (Kallmann) forms are identified depending on the olfactory ability. Clinical and genetic heterogeneities of CHH have been widely explored, thus improving our understanding of the disease's pathophysiology. This work aims to (1) provide a detailed clinical and hormonal description of normosmic CHH patients and (2) identify the mutation linked to the studied phenotype. Participants and methods: We investigated three affected patients with normosmic CHH, belonging to a consanguineous Tunisian family. Patients underwent an insulin-induced hypoglycemia test. We performed whole exome sequencing to identify the causal mutation. Results: At first diagnosis, a total gonadotropic deficiency was identified in all patients. The insulin-induced hypoglycemia test has also revealed a reduced cortisol secretion and complete growth hormone deficiency. At 20.8 years, one female exhibited a spontaneous recovery of the hypothalamic-pituitary-adrenal axis function, unlike her affected siblings who still depend on corticosteroid replacement therapy. Herein, we identified a novel homozygous nonstop mutation (c.1195T>C) in KISS1R gene in all affected subjects. This mutation led to the substitution of the physiologic stop codon by an arginine (p.X399R). Conclusions: Our study highlights the importance of the KISS1R signaling, in gonadotropin-releasing hormone neurons, in the control of reproductive function. Additionally, our data suggests a complex central and peripheral metabolic control of puberty, through the hypothalamic KISS1R signaling. We suggest a mutual link between the hypothalamic-pituitary-gonadal, -adrenal, and -somatotropic axes.

Mariam moalla

Object: In the competitive world of the market economy, every economic unit tries organizing everyday activities. Creating a set of suitable and cost-efficient organizational structures and making competitive products and services, top managers should find the mechanisms of building alternative ways of organizational structures. Methods: This paper presents the traditional and modern management structures, their historical steps, and developed methods. In this footfall of the market economy, companies in developing countries should build their management system’s organizational structure. They should advance a management system, managerial behaviours, and new management styles of developed ones. For this purpose in this research has learned organizational structures of developed companies. The investigation discusses the emergence, formation, and modern appearance of management structures that evaluate organizational structures’ importance in enterprises and companies’ activities, using vivid examples. Findings: Then, it has shown some forms of developed organizational structures of companies with the assessment of their highest role in management. In the conclusions and recommendations, we offer our approaches to solving existing organizational problems using the historical period of development to this day.

Ikboljon odashev mashrabjonovich

The labeling of medications includes the provision of information and instructions as well as a unique identity for the medical product. It is one of the most important sources of information for patients. Good labeling practice is critical to ensuring patients' safe and effective use of products. Misreading the label, insufficient data on the label, inappropriate labeling font, writing style, and placement on the dosage form can all have disastrous consequences. The objective of this study was to assess medication labeling practices among community pharmacists in Libya. A simulated client method (SCM) was used, and the study was carried out in the City of Zawia, where 146 local pharmacies were visited over three months for the investigation (January to March 2023). These visits were made at random, without the pharmacist's knowledge. The findings revealed that all dispensed drugs were not labeled, and none of the practicing pharmacists in any pharmacies visited displayed any drug label, printed or handwritten. The majority of pharmacists did not address or explain significant information to the patient in an effective manner, which led to inappropriate and harmful consumption of medications. The absence of dispensed drug labels reduces the patient's knowledge of the necessary information about the medicine, resulting in a treatment deficit or unsuccessful therapy. Thus, more effort should be made by health authorities to instruct pharmacists to use and work according to international labeling standards or to establish local labeling specifications.

Mediterranean journal of pharmacy and pharmaceutical sciences

Adherence to pharmacological therapies are keys to effective treatments in diabetic patients. Previous reviews found that most adherence measurement studies on chronic diseases used a self-reported scale. However, there is no consensus on the best scale to measure adherence in diabetic patients. The purpose of this systematic review was to identify the potential self-reported scale that could be considered for measuring medication adherence in diabetic patients and to provide recommendations for researchers or clinicians to determine appropriate adherence self-reported scales in diabetic patients. This review follows general guidelines in the implementation of systematic reviews. After further review, it was found that 33 studies met all inclusion criteria from 4 databases (Wiley, Science Direct, Scopus, and PubMed). The articles were done by the PRISMA, while the keywords were determined by the PICO method. Most research was conducted in Asia (69.7%) and America (18.2%) on patients with type 2 diabetes (81.3%), patients in hospitals (54.5%), suffering for 1–6 months (54.5%), and using a cross-sectional study design (78.8%). HbA1c clinic data (57.6%) were used in most studies as biological markers of adherence. The measurement scales of medication adherence in diabetic patients are MMAS-8 (57,.5%), MMAS-4 (12.1%), BMQ (9%), MCQ (6%), ARMS (3%), ARMS-D (3%), GMAS (3%), LMAS-14 (3%), and MARS-5 (3%). This review provides information on the different self-reported scales most widely used in diabetic medication adherence research. Various aspects need to be considered before choosing the scale of adherence.

Much ilham novalisa aji wibowo

Abstract Background: Hansen’s disease is a chronic infectious disease with a wide range of clinical manifestations. The clinical diagnosis must be confirmed by histopathological and bacteriological studies in order to adequately manage the condition and prevent drug resistance. Aim: To perform a clinico-histopathological correlation of skin lesions in all patients with a clinical suspicion of Hansen’s disease. Materials and methods: A retrospective, hospital based, cross-sectional study was conducted in the Department of Pathology, Father Muller Medical College, Mangalore. Skin biopsies of all suspected cases of Hansen’s disease received over a period of three and a half years were included in the study. Haematoxylin and eosin, Fite-Faraco stained sections of all cases were reviewed. The cases were classified according to Ridley–Jopling classification into TT, BT, BB, I, BL, and LL. Clinical details of the patient, including type and site of lesion were obtained from the patient’s medical records. Clinico-histopathological correlation was done for all the cases. In addition, wherever available, the corresponding slit-skin smears were also included. Results: A total of 76 cases were clinically diagnosed as Hansen’s disease. Clinico- histopathological correlation was seen in 33/76 cases (43.42%). The most common histological subtype of Hansen’s was Borderline Tuberculoid (BT) - 24/76 cases (31.58%). Maximum agreement was seen in Mid-borderline leprosy (92.11%). Fite Faraco stain was positive in 21 out of 76 cases. Slit skin smears were available for 55 cases and positive in 20 cases. Conclusion: Due to clinical and morphological overlap, it is imperative to correlate the clinical, histopathological and bacteriological index results in order to accurately subtype the categories in Hansen’s disease.

Archana

The study, “The beginnings of the organization of the Kosovo Liberation Army in the Lap Operational Subzone December 1995 – June 1998,” as its object of study has the period of the Kosovo Liberation War in the years 1998-1999. This study touches upon the historical dimension of the efforts and sacrifices of Albanians found in the Serbian-Yugoslav area against their will.This study’s main topic is the beginnings of the organization in the Lap Operational Subzone (LOSz) as a significant part of the KLA. The study has undergone a scientific analysis based on sources of all kinds. The analysis included LOSz’s position in the KLA structure: the mission and duties during the liberation war, the governing bodies at the beginning of the LOSz organization and their functional organization, as well as the battles and downfalls of the freedom fighters. Historical literature, feuilletons, scientific papers, as well as interviews with famous personalities, were used to shed more light on the organization and the war in LOSz. This topic covers an essential segment of the Kosovo Liberation War period 1998-1999 And contributes towards the complete enlightenment of this historical period, especially in this region. Therefore, hopefully, this study will build interest and create perspectives for new studies of this nature.

Anglisticum

Introduction: During the COVID-19 pandemic, most educational institutions have opted for online education rather than traditional modes of education to protect their employees and students. Online education has been gaining momentum in almost all countries around the world. This coincides with the recently introduced competency-based medical education in India which has embraced online education. This poses a new challenge for the institutions involved, the instructors or teachers, and the students since they must adapt quickly to the new mode of learning. Online education requires teachers to improve their competency in three major areas; pedagogy, technology, and content knowledge. Some of the challenges include; lack of technological skill, poor time management and lack of infrastructure. As technology rapidly advances, health care education systems must also advance in tandem. To implement the new competency-based system and online education, the institutions and the individuals must realize the importance of online education, identify the barriers and quickly work on solutions for success. Methods: This review was conducted based on various research papers on the topic of online medical education, the challenges faced by faculty members, and the opinion of students on this dilemma. Search terms included online medical education, COVID19, competency-based medical education. Conclusion: This review identified various challenges posed by online education on the current medical curriculum, faced by both faculty members and students, especially under the light of the Competency-Based Undergraduate Curriculum for Indian Graduates. Different solutions were proposed to overcome these challenges.

Nirav

Therapies highly plays a crucial role for all those children and adults with disabilities. In this article, We aim to research the Special Educators’ Knowledge about Therapies in various special schools in the city of Hyderabad, Telangana, India. A qualitative approach was taken for this purpose. Questionnaires was used to collect the data. It was found that the teachers did not have proper conception on Therapies. The data indicated that the teachers are unaware about the unconventional therapies such as Drama Therapy, Pet Therapy and Laughter Therapy and there benefits when working with CSN. This lack of awareness needs to be addressed for the enhancement of the teacher as well students capabilities.

Husna habib

Medical science has grown tremendously at a rapid rate over the recent past. This is especially true in the fields of diagnostics and therapeutics encompassing various diseases of all the systems of the human body including psychosomatic disorders. During the past three to four decades, precision in diagnostics has enormously improved due to invention of multiple imaging modalities such as computerized tomography (CT) scan, magnetic resonance imaging (MRI) scan, positron emission tomography scan, ultrasound scanguided studies, CT-guided diagnostic procedures, Doppler studies, arteriography, CT angiography, advanced needle biopsy procedures, histochemistry studies, tumor marker studies, as well as in the ongoing improvements in all diagnostic and therapeutic branches. The surgical advancements due to increasing use of key-hole surgery using scopes such as arthroscope, laparoscope, colonoscope, and bronchoscope have revolutionized the surgical treatments and made surgery safer, less time-consuming, less costly, and less risky with reduced post-operative morbidity. Cardiac catheterization, percutaneous cardiac angiography, angioplasty, and vascular surgery have made the procedures/ surgeries related to the heart and major vessels, much simpler, faster, and safer minimizing the need for big infrastructures or large operative teams.

Karishma

Among the consequences of armed conflict, the effect on the mental health of the civilian population is one of the most significant aspect of psychiatric disorders. Studies of the general population show a positive increase in the incidence and prevalence of mental disorders. This study is aimed to determine the relationship of the national crisis on the mental health conditions of university students and their academic performance. Specifically, this study was aimed to evaluate the national crisis effects on the mental health and the academic performance as well as the association of the national crisis, mental health and academic performance. 40 sample size of pharmacy students at the academic year 2019-2020 at Attahadi University, Tripoli, Libya were used in this study and a survey of validated questionare for mental health was considered. The findings revealed that the effects of national crisis on the mental health of the students disclosed the verbal interpretation of rarely grade. Indeed it can be found that mental health of the students was not of greatly affected in this sample. The academic performance of the students disclosed that academic year levels one and three have verbal interpretation of good and academic year level two has fair. Though the academic performance of the students did not show a verbal interpretation of weak or very weak. It is still worthwhile to note that none of them has reached the very good and the excellent performance. It can be concluded that a need for the students coping strategies be enhanced for them to reach their maximum potential with their academic performance. This study shows also that a weak positive relationship among the variables. Though it’s not that high, indeed, the mental health of the students can be a predictor to their academic performance.

Mediterranean journal of pharmacy and pharmaceutical sciences

Objective: This study was conducted to investigate traditional beliefs and practices of women regarding care of the mother and the infant during pregnancy, in childbirth, and in the postpartum period. Methods: This was a descriptive, cross-sectional study conducted at a public hospital in Istanbul. The data collected consisted of socio-demographic and obstetric characteristics, and responses to questions about some traditional customs regarding pregnancy, delivery, and the postpartum period. Results: In our research, some non-harmful cultural practices were found, such as the belief that to have a clever and beautiful baby the mother should eat fruit; that to have a healthy and peaceful pregnancy, the mother should not look upon ugly things; the mother should indulge her food cravings; and to have an easy birth, the mother should walk and focus on prayers. On the other hand, we also found beliefs that could be harmful, such as wiping the mouth of a baby with a date before breastfeeding, and practices believed to be protective that could cause harm, such as putting a knife under the baby’s bed, fastening a safety pin to the baby’s clothes, and for the mother and child to remain at home for 40 days. Conclusion: While non-harmful and beneficial practices related to maternal and infant health should be accepted and supported as a part of our cultural richness, practices that could be harmful should be prevented in pregnancy classes or with training upon hospital discharge

Reyhan aydin doğan

Efforts to understand the causes of poverty, how poverty is perceived have become important in the fight to mitigate poverty. In Vietnam, studies on the attitudes of poverty in specific populations, such as Vietnamese students, are rare. Thus, this dataset reports the results collected from 180 social work students and non-social work students of Ho Chi Minh City Open University through attitudes toward poverty and poor people in Vietnam. The Attitude toward Poverty Short Form 21-item scale, developed by Yun & Weaver, was used for the data collection. The survey results showed that when looking for causes of poverty, social work students and non-social work students put the most emphasis on structural factors of poverty. However, social work students, compared with non-social work students, consider personal deficiency and stigma more important. In future, this dataset can serve as a reference source for comparative studies on student’ attitudes toward poverty and impoverished persons and for social work education.

Le minh tien

Étudier les phénomènes grammaticaux actuels sans s’interroger sur la longue trajectoire historique qui a servi de support et de canal au français moderne manquerait de pertinence. En effet, une telle étude permet une meilleure compréhension des phénomènes linguistiques contemporains. Ainsi, notre domaine de recherche, la linguistique diachronique, met l’accent sur les connaissances étymologiques de la langue. Il s’agira, pour les besoins de l’article, de rendre compte de l’évolution morphologique du présent de l’indicatif depuis le latin jusqu’au français moderne. Notre curiosité nous poussera à nous interroger sur les raisons qui expliquent l’écart morphologique du présent de l’indicatif entre le latin et le français moderne. En sus, l’étude des variations diachroniques du présent de l’indicatif renseigne sur les formes actuelles de ce temps verbal. Du latin au français moderne, le présent de l’indicatif subit des flottements aussi bien dans ses radicaux que dans ses désinences. Ceci met en chef l’écart formel existant entre le présent latin et celui du français actuel. Toutefois, les phonèmes subirent des transformations selon qu’ils étaient toniques ou atones, radicaux ou désinentiels. Certaines formes se sont maintenues avec modification ou non de sons; d’autres ont complètement disparues du système. Suivant un ordre chronologique et des lois phonétiques cohérentes, nous montrerons que les formes actuelles du temps le plus usuel du système, le présent, ne sont pas le fruit du hasard. De ce fait, la langue moderne gagnerait à revisiter la morphologie des temps verbaux depuis leur origine pour mieux asseoir les difficultés liées à la conjugaison et fournir une explication authentique sur les variations de forme jusque-là ignorées par certains.

Assanvo

This study determined the effectiveness of Differentiated Instruction in the reading comprehension level of the Grade-11 senior high school students, school year 2016-2017. Specifically, it aims to determine the reading comprehension level of the control and the experimental groups in the pre test and post-test; identify if there is a significant difference in the reading comprehension level of the control and experimental groups in the pre-test and post-test results; and identify the strengths and weaknesses in using Differentiated Instruction. Quasi-experimental method was employed in conducting the study. The respondents were the 150 Grade-11 students of a public high school grouped as control and experimental using Parallel technique. Data sources include pre-test and post-test scores, gain scores, classroom observation form, survey questionnaire, and researcher's reflective notes. The qualitative data were analysed using template analysis style and the basic approach of comprehending, synthesizing, theorizing and re-contextualizing to identify common themes and integrating thematic pieces. Based on the classroom observations, survey and researcher's reflective notes, strengths and weaknesses of Differentiated Instruction were observed. Despite the observed and encountered challenges, the statistical analysis has revealed a significant difference between pre-test and post-test results.

Darrel ocampo

In their different ownership structures, business enterprises pursue different strategies towards accomplishing their owners’ needs and interests. At the heart of these accomplishments is the generation of sufficient financial returns to cover obligations as they become due and residual incomes for the owners. It is doubtless that without a grip of financial stability, the survivability of for-profit organizations becomes bleak. Financial management plays and instrumental role in this case. The generation of sufficient information for decision making for the business and investors alike is integrally critical in shaping the progression of the business enterprise. While businesses provide financial statements according to prevailing laws and accounting standards to the public for their consumption in decision making, they are further needed to be accountable to them regarding their performance and investors’ engagements, especially considering that investors are foundational sources of capital for organizational operations.

Zamzam abdelazim

Gastrointestinal parasites constitute a serious problem to poultry production in Africa. But often times they are usually ignored by the majority of farmers. Whereas, it is one of the major leading causes of ill-health and high mortality rates in the poultry industry. This study was conducted to determine the prevalence of gastrointestinal parasites of chicken slaughtered at the Jalingo market. A total of 500 gastrointestinal tracts of local chicken comprising of 250 from males and 250 from females were collected from the poultry slaughtering and dressing section of the Jalingo market, and screened for gastrointestinal helminths using the saturated sodium chloride floatation techniques. An overall prevalence of 28.6% (143/500) was recorded with a prevalence of 16.8% (84/500) in males and 11.8% (59/500) females. Nine different species parasites comprising five nematodes and four cestodes, were recorded. Nematodes were the most predominant intestinal parasite with a prevalence rate of 89 (62.2%). And Ascaridia galli 45 (50.5%) was found to be the most prevalent nematode. Other nematodes observed were Capillaria annulata 13.4% (12/89), Heterakis gallinarum 2.2% (2/89), Strongyloides avium 32.5% (29/89), and Syngamus trachea 1.1% (1/89) having the lowest prevalence. Railliatina tetragona 57.4% (31/143) was the most prevalent cestode recorded. Other Cestodes were Hymenolepis carioca 27.7% (15/54), Raillietina cesticellus 12.9% (7/54), and Davainea proglottina 1.8% (1/54). No trematode was recorded in this study. This study showed that nematodes and cestodes were the common helminth parasites in local chicken. There is therefore the need for educating the farmers on the impact of gastrointestinal parasite infection in chicken and the need to institute good management practices so as to reduce their effects on productivity. Sex of the chicken had no statistically significant difference (X2 = 6.12, df = 1; P > 0.05) on the prevalence of helminths.

Bitrus inuwa

This study was conducted to optimize the integration of solar-photovoltaic-distributed energy resources (SPVDERs) within the Nigerian power system networks using an AI-based Particle Swarm Optimization (PSO) Algorithm. By employing a mixed research method, primary and secondary data were gathered to calculate flow analysis, NR method's equations, PSO's position update model, particle swarm optimizer algorithm, and application modeling including Solar-PV DER modeling. The AI-based PSO algorithm design was developed for optimizing SPV-DER integration in Nigerian power system networks, and key parameters and variables that needed consideration were identified. The study also established how the performance of the AI-based PSO algorithm could be evaluated and compared with other optimization techniques for SPV-DER integration within Nigerian power system networks. The study's results showed that voltage limits were within acceptable ranges, and solar power contributions were estimated at 880.10MW with 46,718 panels needed. The study concluded and recommended that investing in AI-powered tools for efficient power distribution; monitoring and resource optimization for sustainable energy sources would optimize performance and unleash Nigeria's sustainable energy potential.

Fxintegrity publishing

The space-time dynamics of chlorophyll a concentration and seawater excess viscosity has been investigated in the hydrographically contrasting inshore and offshore water masses of the eastern English Channel. This was done during the phytoplankton spring bloom dominated by Phaeocystis globosa before and after the very large-scale formation of foam induced by an increase in wind-driven turbulence and the related wave breakings. The results suggest that the dynamics of chlorophyll a concentration and seawater excess viscosity are differentially controlled by the formation of foam through the intensity of the spring bloom and wind-generated turbulence.

Irma kesaulya

Colon is part of the digestive system in the human body responsible for absorbing water and nutrients from food residues. There are many problems affecting the colon including irritable bowel syndrome, constipation, hemorrhoids, anal fissures, abscess, colitis and colon cancer which considered one of the most common diseases among the Libyan community. The aim of this study was to search the presence of colonic disease and the tendency of those diseases to transform into colonic cancer at Benghazi medical center in Benghazi-Libya. A survey was comprised of 15 questions concerning colon diseases, proper diagnosis and treatment type. The survey was distributed to the physician specialized in medicine at Benghazi medical center and they fill it voluntary. The initial part of the questionnaire designed to obtain demographic data concerning the physicians who diagnose the colon illness. The rest part of the questionnaire was concerning special questions to define frequency of the diagnosed disease. There were 20 participants at this study. The response to all questionnaires were collected and analyzed for drug use, patients and disease distribution. In conclusion, this study demonstrates that the correct diagnosis, prescribing the appropriate treatment for the colon disease and using the medicine properly is one of the most important things that help in treating the disease and reducing its exacerbation. In some cases, eradication procedures may be required if the medicine is not sufficient to treat the disease without the need for operations

Mediterranean journal of pharmacy and pharmaceutical sciences