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Urolithiasis in gel: an in vitro approach for whewellite growth patterns to evaluate risk factors and management of urinary stones

  • Authors Details :  
  • Salman Ahmed,  
  • Muhammad Mohtasheemul Hasan ,  
  • Zafar Alam Mahmood

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Whewellite crystals are most commonly found in the kidneys, ureter and urinary bladder, causing urolithiasis. The present in vitro study aimed to observe the possible growth patterns and morphology of whewellite crystals. The study was carried out in U-shaped test tubes. Bow shape, donuts and their aggregates, dumbbell, platy, prismatic, rosette, styloid, X-shape and tetragonal bipyramidal crystals were observed. Energy Dispersive X-ray, Fourier Transform Infra-Red spectroscopies and Scanning Electron Microscopy were used to characterize the crystals. This study will be helpful in determining the promotion, modulation, and inhibition of the crystals, as well as evaluating risk factors and prophylactic management of urinary stones.

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