Dr. Ashwani Kumar Ghai

To evaluate effects of combination of topical 5% phenylephrine and 0.8% tropicamide on pulse rate and blood pressure

• Authors Details :  
• Shikha Ohlyan,  
• Ashwani Kumar Ghai,  
• Surakshya Rajaure,  
• Nikita Sethi

233 Views Original Article

Background: Dilation of pupil in Ophthalmic OPD is a routine procedure. Whether a sympathomimetic agent like phenylephrine should be used in hypertensive patients is still a question to be answered. This study tries to resolve the issue. Objective: To evaluate cardiovascular effects of combination of topical 5% phenylephrine and 0.8% Tropicamide. Method: Total 150 patients were subjected for this study (male and female) between 30-80 years of age. Combination of 5% phenylephrine and 0.8% tropicamide eye drops was instilled at an interval of 15 minutes thrice in the eyes of each patient. Any change in BP or HR was recorded Result: The data was collected and subjected to appropriate statistical method using R software version 4.2.1. This study has shown no significant increase in Blood Pressure and Heart Rate after instillation of 5% Phenylephrine and 0.8% Tropicamide eye drops except in one case. Conclusion: We conclude that combination of 5% Phenylephrine and 0.8% Tropicamide can be safely used in all patients who come for ocular examination but precautionary measures should be taken in hypertensive patients.

Article Subject Details

• General ophthalmology

Article Keywords Details

• Pulse rate; Blood pressure; Tropicamide; Phenylephrine

Article File

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