Profile Pic of Dr. Ashwani Kumar Ghai Dr. Ashwani Kumar Ghai

To evaluate effects of combination of topical 5% phenylephrine and 0.8% tropicamide on pulse rate and blood pressure

  • Authors Details :  
  • Shikha Ohlyan,  
  • Ashwani Kumar Ghai,  
  • Surakshya Rajaure,  
  • Nikita Sethi

233 Views Original Article

Background: Dilation of pupil in Ophthalmic OPD is a routine procedure. Whether a sympathomimetic agent like phenylephrine should be used in hypertensive patients is still a question to be answered. This study tries to resolve the issue. Objective: To evaluate cardiovascular effects of combination of topical 5% phenylephrine and 0.8% Tropicamide. Method: Total 150 patients were subjected for this study (male and female) between 30-80 years of age. Combination of 5% phenylephrine and 0.8% tropicamide eye drops was instilled at an interval of 15 minutes thrice in the eyes of each patient. Any change in BP or HR was recorded Result: The data was collected and subjected to appropriate statistical method using R software version 4.2.1. This study has shown no significant increase in Blood Pressure and Heart Rate after instillation of 5% Phenylephrine and 0.8% Tropicamide eye drops except in one case. Conclusion: We conclude that combination of 5% Phenylephrine and 0.8% Tropicamide can be safely used in all patients who come for ocular examination but precautionary measures should be taken in hypertensive patients.

Article Subject Details


Article Keywords Details



Article File

Full Text PDF





More Article by Dr. Ashwani Kumar Ghai

Outcome of therapeutic keratoplasty in hopeless microbial keratitis cases otherwise advised evisceration

Purpose: to study the outcome of therapeutic keratoplasty in severe microbial keratitis cases otherwise advised evisceration. methods: a retrospective, single-center clinical audit...

Follow-up regularity in eye-care among disease conscious population in delhi-ncr: a gender-based retrospective study

Abstract---in contemporary society, most females are deprived of proper education, healthcare, job opportunities, etc., to uphold family customs, patriarchal dominance, and occasio...