The research paper aims to find out the relevance of the existing support system for accelerating women entrepreneurship development and how these entrepreneurial support services of various Institutions expedite the process of social inclusion of women. The study has been conducted in the West Tripura District between January to August 2022. A total of 385 women entrepreneurs who were trained under government institutions were considered as the sample size. The primary data was collected directly from the field on basis of secondary information from Government Departments. The purposive sampling method has been deployed to identify the respondents for conducting the sample survey .
Diabetes is a global issue, the diabetes epidemic is expected to continue, and the burden of diabetes causes catastrophic expenditure for healthcare system. The current study aimed to determine the presentation, the clinical feature and cardio-vascular risk factors in patients with diabetes. A retrospective observational study had been conducted in out-patients department at Almustaqpal Almosherq Centre during September, 2013 till September, 2020, the total number of attended out-patients department were 1 024, 820 patients who were selected for this study. A special perform was completed for every patient, which included details about patient’s demographics, points in clinical history, relevant investigations and clinical examinations were recorded. The study reported that out of 820 patients, 66% (n = 538) was female and their age range was between 14 - 87 years with a mean age of 56.53 ± 13.49 years, 96% (n = 791) were clinically diagnosed as type II diabetes, 07% of the patients were diagnosed as pre-diabetes, the duration of diabetes ranged from newly diagnosed to more than 10 years, with 46% (n = 379) of the studied population were more than 10 years diabetes duration, 70% (581) were presented with classical symptoms of diabetes. Initial treatment for diabetes also different in the studied sample, were absent of anti-diabetic medications in 30% (n = 248) of the patients, they refused to start glucose lowering drugs, 34.6% (n = 284) of them have morbid obesity (body mass index is more than 40), 80% (n = 662) have high HBA1c (more than 8 g%), 40.3% (n = 240/596) were uncontrolled hypertension on anti-hypertension drugs, 95.6% (n = 682/713) were controlled on treatment of lipid lowering drugs. This study showing the presentation of diabetes were the common, type II diabetes, at age group between 41 - 66 years about 65%, female sex, with high body mass index, high glycated hemglobulin and uncontrolled hypertension. There is concern that diabetic patients were occurring at a high frequency in younger adults, where longer duration of illness could increase the risk of developing more complications in later life. The rate of coexist cardiovascular risk factors (hypertension, dyslipidaemia and obesity) in Libyan patients with diabetes is highlighted.
Mediterranean journal of pharmacy and pharmaceutical sciences
The current study was conducted to explore the antiemetic activity of two marine algae, Iyengaria stellata Børgesen (Phaeophycota) and Valoniopsis pachynema Børgesen (Chlorophycota), by chick emesis model. Emesis was induced by copper sulphate (50 mg/kg), and the extracts were tested orally at 150 mg/kg. Chlorpromazine (150 mg/kg orally) was used as a standard antiemetic drug. The results showed that methanol extracts of both seaweeds have antiemetic activity.
The 2019 coronavirus disease (COVID-19) was declared by the World Health Organization as a pandemic on 11th March, 2020 which spread rapidly all over the world. COVID-19 disease has different clinical presentations, ranging from asymptomatic to severe symptoms. Laboratory findings are important in determining which therapeutic strategies to seek and to identify severe cases initially. In this study, we compared the results of C-reactive protein, D-dimer, blood electrolytes and mean corpuscular hemoglobin concentration between survivors and non-survivors of 22 Libyan patients with COVID-19 present in the intensive care unit at Maitika Isolation Center (Tripoli, Libya) in the period of January to June 2021. We could not detect any significant difference in C-reactive protein between survivors and non-survivors but a significant difference in D-dimer level was observed. Non-survivor COVID-19 patients have a higher level of D-dimer. Moreover, a statistical significant difference in chloride and sodium levels but not in potassium level were detected. A marked lower of mean corpuscular hemoglobin in non-survivor than survivor COVID-19 patients was shown. Thus, these parameters could act as biomarkers for COVID-19 patients.
Mediterranean journal of pharmacy and pharmaceutical sciences
Concrete is a material which is used in construction. Weight of concrete plays a major role in the construction industry. If the weight of the concrete is increased, it will pose more structural problems on the later date of construction. It also increases the cost of construction, without any specific benefit. So if lightweight concrete is used, it not only reduces cost of construction, but also not poses any structural problems unnecessarily. Light weight concrete also aids workers in smooth handling of materials. In this study, vermiculite in the form of exfoliated form is used to replace partially natural sand. By this action dead weight of the structure is reduced. Once the dead weight of structure is reduced, it in turn reduces cost of construction. In this study three mixes were casted with the cement content of 383 kg/m3 in M20 concrete and the water cement ratio of 0.45 is chosen. Vermiculite at 10%, 20% and 30% are choosing to partially replace the natural sand. The Tests conducted on concrete for evaluating mechanical properties include compressive strength and split tensile strength. For evaluating durability properties, tests like acid resistance, sulphate resistance, chlorine penetration and water absorption.
Rhizosphere actinomycetes are promising biocontrol agents for use in agriculture and have been isolated from various plant species. In the present investigation, actinomycetes were isolated from rhizospheric soil of maize to test antagonistic activity against Fusarium verticillioides and fungal strain (T. viride) were procured from National fungal culture collection of India (NFCCI), T. harzianum and A. niger were isolated from soil to test their antagonistic effects against Fusarium verticillioides. In the present study bio-control dual inoculum method were followed to evaluate the bacterial and fungal strains against the pathogen and reveals that Single Bacterial Inoculum (SBI) of S. cinereus shows more effective in controlling the growth of Fusarium verticillioides (28 mm in treated plate) compare to control (45 mm fungal growth). But in Dual Bacterial Inoculum (DBI), the combination of S. albosporous and S. cinereus shows more effective (08 mm fungal growth in treated plate) compare to control (52 mm fungal growth). Similarly, in Single Fungal Inoculum (SFI), T. harzianum were more effective (18.8 mm fungal growth) and in Dual Fungal Inoculum (DFI), T. viridae and T. harzianum act as a more effective (2.5 mm fungal growth) against Fusarium verticillioides compare to controls (60 mm and 52 mm fungal growth respectively). Overall interpretation of the present work reveals that DBI and DFI were more effective than SBI and SFI against Fusarium verticillioides.
Nano technology refers to enhancing the function and delivering the upcoming smart solutions to products at the nanoscale level. It relates to organizing the molecules for altering in dimension and characteristic for improvement like smart fabric. These fabrics could assist producers with the added prominence on a standard of living, visual attraction, and system wanted technological produces. Nanosize particles can unveil unpredicted characteristics dissimilar from the bulk matter. The fundamental principle is that the features could radically be altered after the material is decreased to the nanometer scale. Nanotechnology has multipurpose functions in fabric manufacturing in producing the stain and wrinkles defiance, flame retardant, antimicrobial and antistatic properties, moisture control, ultraviolet protection, and release features. The nanomaterials inside the fabric could influence numerous qualities, comprising reduction, electrical conductivity, flammability, and strength. Nanotechnology has additionally created a significant impression on various application and implementation. Nano-doctored fabrics may advance numerous fabrications as the nano-science progresses further.
Newcastle Disease Virus (NDV) constitutes a major constraint to the poultry production system in Nigeria. This study was carried out to investigate the seroprevalence of NDV antibodies in local chickens (Gallus domesticus) slaughtered in five different live bird markets (LBMs) in Kaduna metropolis, Nigeria. Three hundred blood samples were collected and screened for antibodies against NDV using Haemagglutination Inhibition (HI). An overall seroprevalence rate of 23% (95%:CI18.5-28.0) was recorded in this study. Seroprevalence based on different LBMs revealed a higher prevalence of 28.3% (95% : Cl 18.0-40.7) in Sabo market, followed by Sokoto road market 26.7% (Cl:16.7-38.9), Kawo market 18.3% (95% Cl: 10.0-29.6), Railway market 13.3% (Cl:6.4-23.5), and the lowest prevalence was recorded in central market 11.7% (Cl:5.2-21.7). The difference in seroprevalence among the LBMs was not statistically significant (p > 0.05). Higher seroprevalence of NDV antibodies in female birds 30.5 % (Cl: 24.1-37.6) was recorded compared to male 13.9% (Cl: 8.3-21.4). The study indicated that NDV is endemic in the population. LBMs location had no significant influence on the seroprevalence of NDV in the study area. The difference in seroprevalence between sexes was statistically significant (p < 0.05). Therefore, this study demonstrated the need for a regular strategic vaccination programme against NDV in local chickens in Kaduna metropolis.
Parkinson’s disease is a common movement disorder associated primarily with oxidative stress-mediated degeneration of dopaminergic neurons. Earlier studies showed that Sorghum bicolor-based supplement (SbS) exhibited antioxidant and neuroprotective activities and might likely rescue the death of dopaminergic neurons in Parkinson’s disease. This study examined the effect of SbS on rotenone-induced Parkinsonian-like motor deficits in rats and the involvement of oxidative stress and pro-inflammatory cytokines. Rats were divided into six groups and treated orally with sunflower oil (vehicle-control), rotenone (2.5 mg/kg) alone or in combination with each dose of SbS (50, 100, and 200 mg/kg) and levodopa-carbidopa (10 mg/kg) on an alternate day for 28 days. The changes in motor functions were evaluated on day 28 and the brain concentrations of oxidative stress biomarkers and pro-inflammatory cytokines (tumor necrosis factor-alpha and interleukin-6) were determined. Rotenone caused motor deficits by impaired locomotor activity in the open field test and induced catalepsy in the bar test, which were attenuated by SbS. Rats pretreated with SbS had reduced brain levels of malondialdehyde, nitrite, and pro-inflammatory cytokines compared to rotenone controls. SbS mitigated rotenone-induced depletion of reduced glutathione and antioxidant enzymes in the rat brain. The results suggest that SbS ameliorated rotenone-induced Parkinsonian-like motor dysfunctions by reducing neuronal oxidative stress and pro-inflammatory cytokines in rats.
Mediterranean journal of pharmacy and pharmaceutical sciences
Background: Idiopathic Parkinson's disease (PD) is a central nervous system degenerative disorder with an unknown etiology. PD is the second leading cause of neurological impairments. Exercise therapy treatment is commonly used for PD to improve health and decrease the functional limitations. Exercise therapy includes Strengthening, aerobic, agility etc.. Objective: To investigate the evidence on efcacy and limits of strength training in rehabilitation of Parkinson's disease Method: A comprehensive search on pubmed, clinical keys database using keywords Parkinson's disease, physical therapy, strength training ,resistance training. The studies including Randomized controlled trails and systematic reviews published since 2005 are reviewed. Results: 36 studies identied through database searching. 25 studies are excluded due to duplicates, irrelevance, based on titles, outcome diversity. 5 systemic reviews and Meta analysis, 6 RCT are included. Review and analysis of articles is going on Conclusion : The result of this review suggests that strength training program can be effective in people with mild and moderate parkinson's disease. It can improve functional independency with increased muscle strength, gait parameters, posture and balance, all of these positive role on participation and quality of life.
Political participation of women is essential for the functioning and vitality of any democracy. In India, despite constitutional provisions and various initiatives, women's participation in politics remains significantly lower than that of men. This study aims to delve into the factors influencing women's political participation in Indian democracy and explore avenues for their empowerment in the political sphere. Through a comprehensive analysis of existing literature, data, and case studies, this article examines socio-cultural, economic, and institutional barriers that hinder women's entry into politics. Additionally, it highlights successful initiatives and policy measures undertaken at various levels to enhance women's political participation. The study underscores the importance of addressing structural inequalities, promoting gender sensitive policies, and fostering a conducive environment for women's engagement in politics. By advocating for inclusive and equitable political representation, this research contributes to the ongoing discourse on women's empowerment and democratic governance in India.
Brain tumors (BTs) are deadly diseases that can strike people of every age, all over the world. Every year, thousands of people die of brain tumors. Brain-related diagnoses require caution, and even the smallest error in diagnosis can have negative repercussions. Medical errors in brain tumor diagnosis are common and frequently result in higher patient mortality rates. Magnetic resonance imaging (MRI) is widely used for tumor evaluation and detection. However, MRI generates large amounts of data, making manual segmentation difficult and laborious work, limiting the use of accurate measurements in clinical practice. As a result, automated and dependable segmentation methods are required. Automatic segmentation and early detection of brain tumors are difficult tasks in computer vision due to their high spatial and structural variability. Therefore, early diagnosis or detection and treatment are critical. Various traditional Machine learning (ML) techniques have been used to detect various types of brain tumors. The main issue with these models is that the features were manually extracted. To address the aforementioned insightful issues, this paper presents a hybrid deep transfer learning (GN-AlexNet) model of BT tri-classification (pituitary, meningioma, and glioma). The proposed model combines GoogleNet architecture with the AlexNet model by removing the five layers of GoogleNet and adding ten layers of the AlexNet model, which extracts features and classifies them automatically. On the same CE-MRI dataset, the proposed model was compared to transfer learning techniques (VGG-16, AlexNet, SqeezNet, ResNet, and MobileNet-V2) and ML/DL. The proposed model outperformed the current methods in terms of accuracy and sensitivity (accuracy of 99.51% and sensitivity of 98.90%).
Abstract---In contemporary society, most females are deprived of proper education, healthcare, job opportunities, etc., to uphold family customs, patriarchal dominance, and occasionally negligence towards the feminine gender. According to researchers, gender inequalities in health care, especially in eye care, are evident between accessing the care and getting treatment in developing countries. Therefore, we aim to measure the gender-wise eye-care follow-up regularity in accessing long-term glaucoma consultation among various age groups with a sample size of 564 in Delhi-NCR, India. The age groups (in years) are 15-29 (Group I), 30-44 (Group II), 45-59 (Group III), 60-74 (Group IV), and 75 and above (Group V). Groups I to V show, intragroup males have higher odds of getting regular eyecare by 20% (OR 1.20, 95% CI 0.413 to 3.4871), 2.08% (OR 1.0208, 95% CI 0.4637 to 2.2472), 3.4% (OR 1.034, 95% CI 0.6369 to 1.6787), 8.46% (OR 1.0846, 95% CI 0.6783 to 1.7344), and 45.83% (OR 1.4583, 95% CI 0.4575 to 4.6484) respectively. The probable causes of gender-wise irregularity are lack of seriousness, financial limitations, dependency, loneliness due to widowhood, etc. To make eye-care services equally accessible to everyone, healthcare agencies should first take various progressive policies to overcome gender-wise socio-economic barriers.
A medication error is any preventable event that may cause or lead to inappropriate use of drugs or patient harm if it is not under the control of the health care professional. Despite the fact that healthcare professionals take the responsibility very seriously, it has been estimated that 250 000 Americans die annually due to medication errors. Although, estimates show that one in ten patients worldwide is affected by medication errors while receiving hospital care, the harm can be caused by a range of incidents or adverse events. The exact incidence of medication errors in the neonatal intensive care unit (NICU) is unknown. In neonates especially premature infants, the immaturity of developing body systems affects the absorption, distribution, metabolism and excretion of drugs and therefore an exponential risk for medication errors is present. The risk of medication errors in children are much greater than adults.
Mediterranean journal of pharmacy and pharmaceutical sciences
Objective: This study fills an important research gap by focusing on the effectiveness of low-impact exercise in Parkinson's disease (PD), taking into account the different challenges faced by people with varying degrees of disease severity. Motivation: Unlike generic investigations into exercise and PD, our research prioritizes low-impact activities, considering safety concerns related to balance deficits and coordination challenges in the PD population. The study aligns with a patient-centred approach, aiming to provide a safer alternative to traditional exercise modalities. Approach: Conducting a comprehensive literature review, we conducted an online literature search on various databases, specifically investigating about low-impact exercises on both motor and non motor symptoms in PD individuals. Review process involved capturing diverse intervention types, durations, frequencies, and intensities. Findings: The amalgamation of diverse outcome measures, including UPDRS, Berg Balance Scale, TUG, 6MWT, and PDQ-39, showcased the multifaceted impact of low-impact exercises on both movement related and non-movement related symptoms. Notably, aerobic exercises being treadmill walking, cycling, and group sessions, emerged as pivotal interventions, demonstrating improvements in gait, balance, flexibility, and overall quality of life for PD individuals. Conclusion: While acknowledging limitations, such as potential publication bias and a focus on aerobic exercises, this study provides meaningful decision making information for clinicians and researchers. Future research should diversify interventions and methodologies to enhance the evidence base and address nuanced aspects of low-impact exercises in PD management. The results of this review contribute to the existing body of knowledge regarding the nuanced benefits of personalized low-impact exercise for Parkinson's disease.
Cloud computing is used to achieve sustainability in terms of computing. It reduces energy and resource consumption. Most of the companies have been moving their applications to the cloud to reduce power, energy re-source, and carbon emission. Today's computing landscape is rapidly shifting toward creating applications to leverage Cloud platforms to have necessary features such as elasticity, virtualization, low cost, and pay-per-use. Cloud computing's rising demand and versatility are achieving acceptance in the research community as a means of implementing large-scale electronic systems in the format of workflows (set of tasks). One of the most important objectives of this effort is to trim down makespan which is the total period taken by the resources to complete all workflow activities. Another foremost objective of this work is to satiate all the user-delineated time constraints while scheduling workflow activities.
The adulteration and substitution of crude drugs is a burning problem. No doubt, substitution is helpful in places where the unavailability of particular oil drugs and or unwanted adverse effects of the desired crude drugs are there and have a choice of another drug with similar pharmacological effects and less unwanted aftereffects. However, in most cases, it is unacceptable because the conversion of authentic drugs into substandard medications may cause a variety of adverse effects, from mild and moderate to severe life-threatening reactions. So, understanding all the ways of adulteration and substitution is necessary to rectify this illegal act and maximize consumers' safety. At the end of this review, the Botanical Adulterant Program of the American Botanical Council is also highlighted.
Background Type 2 diabetes and obesity are serious public health concerns globally and a growing burden in Africa. Both conditions have serious repercussions on health when they co-occur, yet the extent of their co-occurrence in Africa remains unknown. Therefore, this review aimed to identify the prevalence and associated factors of overweight and obesity among persons with type 2 diabetes in Africa. Method A systematic search was conducted on PubMed, MEDLINE, Embase, African Index Medicus (AIM), and African Journals Online (AJOL) for observational studies that reported the prevalence of overweight and/or obesity among type 2 diabetes patients in Africa. The prevalence data from individual studies were aggregated through a random-effects meta-analysis. The I2 statistic was used to evaluate between-studies heterogeneity, while subgroup analysis and mixed-effects meta-regression were performed to identify sources of heterogeneity. We assessed publication bias using funnel plots and Egger’s test. This review adhered to the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) guidelines. Results Of 1753 records retrieved, 80 articles were eligible for this review, with 74 cross-sectional studies included in the meta-analysis. The pooled prevalence of overweight and obesity was 35.6% and 25.6% respectively, while the overall prevalence of both overweight and obesity was 61.4%. Also, the pooled prevalence of both overweight and obesity across the five geographical areas in Africa ranged from 56.9% in East Africa to 88.5% in Southern Africa. Nineteen factors were significantly associated with overweight and obesity among patients with type 2 diabetes. Conclusion The high prevalence of overweight and obesity among patients with type 2 diabetes is a significant public health concern that transcends geographical boundaries within Africa. The findings from this review highlight the need for innovative weight management interventions that are tailored to the cultural context of the African setting
The high density of H-CRAN associated with frequent UE handover may degrade the throughput. The infrastructure equipment like RRHs and BBUs consumes more energy to reduce UE energy consumptions. In this paper, we propose a utility-based joint power control and resource allocation (UJPCRA) algorithm for heterogeneous cloud radio access network (H-CRAN). In this framework, the power consumption of baseband units (BBUs), remote radio heads (RRHs), and macrocell base station (MBS) are estimated by predicting their dynamic loads. The data rate achievable for UE associated with each RRH and MBS on resource block RBk is then estimated. The user wishing to connect to a RRH or MBS then checks the corresponding utility with minimum expected energy consumption and the maximum expected data rate. If any UE with high priority traffic connected to MBS could not achieve its desired data rate requirements, then it can cooperatively seek the assistance of any RRH for assigning the balance RBs. The throughput may be enhanced by the high density of H-CRAN and frequent UE handover. Inter- and intracell interference causes the H-CRAN macrocells’ improved data rate to diminish. To lower UE energy consumption, infrastructure devices like RRHs and BBUs need more energy. As a result, there is a trade-off between operators and UE energy conservation. It is possible to determine the power consumption of BBUs, RRHs, and MBS using predictions of their dynamic loads. The UE may then forecast the data rate for each RRH and MBS on the resource block. When a user wishes to connect to an RRH or MBS, they look at the utility with the highest expected data rate and the least predicted energy usage first. A UE with high priority traffic connected to the MBS can cooperatively ask any RRH for assistance in allocating the remaining RBs if it is unable to achieve its intended data rate needs. Experimental results have shown that the proposed JRAUA algorithm achieves higher throughput, resource utilization, and energy efficiency with reduced packet loss ratio, when compared to the existing techniques.
The main focus of this paper is to examine the relationship between insecurity in Nigeria and how traditional institutions such as traditional monarchical system can be used as veritable tool to curtail increasing insecurity in a democratic system such as Nigeria. The pervasive nature of insecurity,though,not an entirely Nigerian problem, has been trending of late, andhence, become a huge source of worry for scholars,experts,public commentators and the international community at large.The menace of insecurity finds expression in wanton killings, kidnapping,farmers-herders conflicts, rape, communal clashes, militia activities, ethnic secessionist agitations and many other strands of violence. The multiplier effects of all these challenges have been very devastating in terms of the recent attacks witnessed all over the country in recent times. This study observes that most of the people engaged in some of these atrocities might be well known to traditional rulers in the communities where they come from. This is because traditional rulers are closest to the people. The work is an exploratory study and relies solely on literature and works of experts in the broader field of security studies for investigation. The paper sums up a conclusion and recommends that there is a need for the adoption of both vertical and horizontal approaches to tackle the menace of insecurity, particularly, using the instrumentality of traditional institutions as a point of departure.
Department Of Orthopedics, University Faculty Of Medicine
Dr Vishwanath Karad Mit World Peace University
Department Of Mathematics, National University Of Skills (nus), Tehran, Iran.
Police Academy, Egypt