A simple and rapid RP-HPLC method has been developed and validated for the simultaneous determination of Levocloperastine fendizoate and Chlorpheniramine maleate syrup formulation. Resolution of the analytes was achieved within 10min, employing a mixture of 10mM mobile phase Buffer (pH 6.5): Acetonitrile (50:50, % v/v) as isocratic mobile phase, pumped at 1.0mL/ min through a C18 column (5μm particle size). The detection wavelength for the analytes was 227nm. The system suitability parameters were found to be acceptable. The linearity of response (r2>0.999) in the appropriate ranges (from 50% up to 150% of the expected concentrations of the analytes in the formulations), method accuracy (RSD<2.0%), repeatability and intermediate precision (RSD<2.0%), were confirmed. Robustness result indicates that the methods performance can withstand small variations in method parameters. Satisfactory results obtained in terms of analyte recovery and RSD, while analyzing marketed pharmaceutical preparations. Hence the method can be useful for regular analysis of this combination in marketed syrup formulation.

Prasanna pradhan

The current study seeks to develop and validate a high-performance liquid chromatography method for atorvastatin diastereomer separation and analysis. In particular, we wish to identify the many diastereomers in atorvastatin, which can help us to better understand their pharmacological properties and provide significant information for pharmaceutical applications. Atorvastatin was chromatographed on a Chiralcel® OD-RH column and n-hexan-2-propanol (95:05 v/v) as the mobile phase, with an injection volume of 10 µL. The solution was pumped at a continuous flow rate of 1 mL/min, with a detection wavelength of 260 nm. The investigation found two peaks with retention times of 3.23 and 3.85 min, respectively. The resolution, capacity, and selectivity factors obtained were Rs = 1.2, k′1 = 3.50, k′2 = 4.37, and α = 1.24.

Mediterranean journal of pharmacy and pharmaceutical sciences

Objective: To determine the association between oral health literacy, oral hygiene and gingival health status. Methods: This cross-sectional study was conducted among patients attending University of Benin Teaching Hospital, Benin City. Data were collected through interviewer-administered questionnaires. Index used in this study for estimating oral health literacy levels was Rapid Estimate of Adult Literacy in Dentistry- 30 (REALD-30). The participant’s oral hygiene status was assessed using the Simplified Oral Hygiene Index while gingival health was assessed using the Gingival Index. Results: Two hundred and eight participants with 130 (62.5%) males and 78 (37.5%) females formed the population of the study and their mean age was 28.32 ± 10.5 years. The prevalence of low oral health literacy was 86 (41.3%). The oral hygiene status of most of the participants 100 (48.1) was fair. The prevalence of gingivitis was 58.2%. Oral health literacy had significant statistical negative correlation with age, oral hygiene and gingival health status. Oral health literacy consistently emerged as a predictor of oral hygiene and gingival health status. Conclusion: Majority of the participants with low oral health literacy had fair/poor oral hygiene status (p = 0.000, OR= 17.870, 95% CI = 7.320-43.627) and gingivitis (p = 0.000, OR= 7.054, 95% CI = 3.514-14.164).

Hope inegbenosun

The current study explored the anti-emetic activity of six aromatic medicinal plants viz Carissa carandus L.. Cichorium intybus Cinnamomum tamala L.. Lallemantia royleana Benth. Matricaria chamomilla L., and Piper metysticum G. Forst . Anti-emetic activity was assessed using a chick as an anti-emetic model. The ethanol extracts of these plants were administered at 150 mg/kg BW orally. Lallemantia royleana and Piper metysticum showed a significant (P <0.001 ) decrease in retches induced by copper sulphate pentahydrate given orally at 50 mg/kg BW. Domperidone was given at 100 mg/kg as a reference drug.

Dr. salman ahmed

Jobelyn® is a multi-functional natural dietary supplement made from Sorghum bicolour with very high anti-oxidant and anti-inflammatory capacities. The study investigated the role of Jobelyn® in the attenuation of oxido-inflammatory markers induced by tramadol use, abuse and discontinuation over 17 days in rats. The experimental observational study was carried out using male adult albino rats weighing between 100 and 170 g. The experimental design involved five groups. Rats were randomly divided into groups of five, consisting of group 1 (normal control rats), and group 2 (rats treated with tramadol at 40 mg/kg/day) were administered for 10 days and discontinued for seven days. Group 3 administered incremental doses of tramadol from 40 mg/kg/day to 100 mg/kg/day over 10 days and discontinued for seven days. A similar treatment protocol was administered for group 4 and group 5 but were treated with Jobelyn® at a dose of 200 mg/kg/day at the discontinuation phases for seven days. Behavioral assessments (elevated plus maze model of anxiety and open field model of locomotor activity) and biomarkers of oxido-inflammatory stress were assessed. Tramadol-treated groups had significant anxiety responses and locomotory deficits in comparison to the control group. Tramadol-treated groups had significant elevations of nitrites and malondehyde and reduced enzymatic markers such as catalase, glutathione, reduced glutathione, superoxide dismutase, G-s-transferase, glutamic acid decarboxylase and increased activity of acetylcholinesterase when compared to control group. Administration of Jobelyn® attenuated the responses and ameliorated the oxido-inflammatory biomarkers similar to levels in control group. Tramadol induces oxido-inflammatory stress markers in the prefrontal, striatum and hippocampus in rats. Anxiety and locomotory behavioral actions on tramadol treatment were elevated despite discontinuation for seven days. Thus, Jobelyn® at 200 mg/kg/day ameliorated oxido-inflammatory markers induced by tramadol and decreased anxiety responses in albino rats.

Mediterranean journal of pharmacy and pharmaceutical sciences

The present study focused on analysing the FDI inflow in Electronics industry form year 2007 to 2018 in country and role of FDI in development of the electronic industry in India. As well identify the current status of Electronics industry in world and the share of India in the same. The present research work also attempted to take overview of various policies introduced by Government of India to promote the FDI in Electronics industry. The FDI inflows statistics reveals that the separate category of Electronics sector is created in year 2007 by DIPP for recording FDI inflow. And sector specific data published in DIPP factsheet revels that this industry has attracted 0.55 % of total cumulative FDI inflow in country till December 2018 which is very negligible share of overall FDI in country. The overview of policies revels that NPE–2012 to New NPE-2018 had attempted to provide multiple incentives for Foreign Investors to establish their electronic manufacturing facilities in country but very negligible response has been seen in response of the same. Further results of study reveals that due to various FTA’s & being signatory of WTO’s ITA-1 in year 1996 leads toward reducing competitiveness of electronic manufacturing in India and country become net importer of approximately 50% of overall domestic need of electronics products.

Anshuman vijay magar

Fresh water crab was exposed in fluoride water at 96h the rate of oxygen uptake was higher in gills followed by hepatopancreas and muscle. On exposure to fluoride water, tissue respiratory rates decreased, effect on gill tissue appeared to be more pronounced than other tissues under the study. The rate of oxygen uptake in male was higher tha control animal. Rate of oxygen consumption showed a significant decrease in both sexes with increase in duration of exposure to fluoride.

.vijay digambar suryawanshi

Urolithiasis is a common worldwide problem with high recurrence. This review covers Convolvulaceae seven (07), Costaceae four (04), Ebenaceae four (04), Fagaceae six (06), Hypericaceae eight (08), Lauraceae nine (09), Liliaceae twelve (12) and Lythraceae three (03) plants used globally in different countries. Hopefully, this review will be helpful for the general public and attract the scientific world for antiurolithiatic drug discovery.

Dr. salman ahmed

This paper examines the utilisation pattern of e-resources by faculty of the Kempegowda Institute of Medical Sciences (KIMS) Bangalore. The purpose of the study is to understand the utilisation pattern of E-resources and frequency of access to the internet by the faculty members of KIMS. The faculty members of health science universities and/or medical colleges are engaged in teaching, research, and their information needs and expectations are diverse and varied. Realising the importance and usefulness of the E-resources, most of the colleges in India and elsewhere generously invested in procuring and create access to eresources to support information needs, teaching, learning, and research studies. The paper highlights the usage of different types of e-resources in health sciences, and also the application of web browsers and search engines in this context by the faculty members of KIMS. The levels of satisfaction among faculty members of KIMS towards the E-resources and barriers in using E-resources have been identified in this study.

Subhash reddy b

Territorial disputes in the South China Sea have long been one of the most critical and complex issues of security between south-east Asian states and China. The competition for maritime rights has emerged as the most important security issue in the east Asia. The powerful states have a tendency for domination. The smaller states may not show their dominating behavior over other states, but they have tendency to maximize their relative power by making alliance with great power or by other means. Since the smaller states are not capable enough individually to ensure their own security or to use military force against threatening power, they have tendencies to join in alliances or in other words to create balance of power to ensure their own security. This study attempts to analyze the behavior of small states and to find out which theory matches with the behavior. The behavior of small states like Vietnam and the Philippines cannot be well-explained by the realist approach. They behave to make their existent clear and safeguard themselves only. Making allies with great powers as well as economic ties simultaneously with other economic powers render their behavior of having peaceful coexistent with everyone.

Muhammad faruq-uz-zaman

Experimental trials were conducted on the compatibility of urea 2% with insecticides of different groups viz., monocrotophos 36SL @ 500 ml/ha, cypermethrin 25EC @ 125 ml/ha, quinalphos 25EC @ 1000 ml/ha and novaluron 10EC @ 375 ml/ha against larval population of Helicoverpa armigera in the field conditions on chickpea cultivar “HC-1” during Rabi season 2011-12 and 2012-13 at CCS Haryana Agricultural University, Hisar (Haryana). These insecticides were found compatible with urea. Minimum larval population of H. armigera was recorded in novaluron 10EC @ 375 ml/ha at 3, 7 and 10 days after spraying. Monocrotophos 36SL @ 500 ml/ha, quinalphos 25EC @ 1000 ml/ha and cypermethrin 25EC @ 125 ml/ha could not provide consistent results against H. armigera. The larval population, pod damage and incidence were statistically at par with insecticides and their combination. No phytotoxicity effect was observed on the leaves with urea application in combination with insecticides. Minimum per cent pod damage (7.3%), maximum grain yield (14.6 q/ha) and monetary returns (` 6265/ha) was realized from novaluron 10EC @ 375 ml/ha plus 2% urea as compared to other treatments.

Dr. babu lal jat

Lateral epicondylitis, commonly known as Tennis Elbow, affects approximately 1-3% of the population. Despite the absence of histological evidence of inflammation in the affected tissue, the term “epicondylitis” implies inflammation. The Extensor Carpi Radialis Brevis (ECRB) muscle is primarily affected, and the condition is attributed to excessive use of this muscle. Non surgical treatment options, such as rest, physiotherapy, cortisone injection, platelet-based therapies, and restricted movements, are recommended. Surgical intervention is suggested for cases involving physical impairment or chronic pain. This review aims to provide healthcare professionals with an understanding of the condition, including its causes, symptoms, diagnosis, and treatment planning options.

Saran malisorn

Phycochemical and pharmacological studies were carried out on Ulva fasciata Delile. The ash content was found to be 20.4812 % dry weight, moisture content 14.5514 %, and total fat content as 0.1878% and 0.49341 %. Total carbohydrate was found to be 54.5301-54.2246% dry weight, phenolic content was found to be 0.022%, flavonoids were found to be 0.0313%, and tannins were 0.00003 %. Ulva fasicata showed central analgesic activity and significant anti-inflammatory activity at 400 mg/kg bw.

Dr. salman ahmed

Introduction: The right lung has two fissures, an oblique and a horizontal, dividing it into three lobes namely the upper, middle, and lower. The nature of the fissure is of great importance in planning operative strategy for thoracoscopic pulmonary resection where an the incomplete fissure may contribute to post-operative air leakage Aim: To assess the gross morphological features of the right lung with special emphasis on the completeness of horizontal fissure. Material & Method: Material for the present study comprised of right lungs obtained from 50 well-embalmed adult human cadavers of both the sexes dissected as a part of 1 MBBS curriculum in the Department of Anatomy, Govt. Medical College, Amritsar. Results: Horizontal fissure was found to be complete in only 10% of the lungs while in rest 90% it was either incomplete or absent. Conclusion: Inferable from the huge variation in nonappearance or partial appearance of horizontal fissure in the right lung and to the absence of an acceptable classification of fissures, an endeavor has been made to give one such classification. In like manner, the horizontal fissure is evaluated from Grade zero to IV contingent on its absence and profundity from coastal surface to the hilum. Each evaluation is additionally divided into 3 subgrades relying on the culmination or incompleteness of these fissures with respect to their length.

Dr kulbir kaur

Currently, the use of internet-connected applications for storage by different organizations have rapidly increased with the vast need to store data, cybercrimes are also increasing and have affected large organizations and countries as a whole with highly sensitive information, countries like the United States of America, United Kingdom and Nigeria. Organizations generate a lot of information with the help of digitalization, these highly classified information are now stored in databases via the use of computer networks. Thus, allowing for attacks by cybercriminals and state-sponsored agents. Therefore, these organizations and countries spend more resources analyzing cybercrimes instead of preventing and detecting cybercrimes. The use of network forensics plays an important role in investigating cybercrimes; this is because most cybercrimes are committed via computer networks. This paper proposes a new approach to analyzing digital evidence in Nigeria using a proactive method of forensics with the help of deep learning algorithms - Convolutional Neural Networks (CNN) to proactively classify malicious packets from genuine packets and log them as they occur.

Dr. chandrashekhar uppin

India is a country of immense diversity. It is home to people of many different racial, languages, ethnic, religious, and national backgrounds. Groups of people in India differ from each other not only in physical or demographic characteristics but also in distinctive patterns of behavior and these patterns are determined by social and cultural factors like language, region, religion, and caste. Apart from behaviour, economic development, level of education and political culture of the people in various social segments differ from region to region. More you can say that economy and cultures have been enriched by the contributions of migrants from round the globe. In an increasingly globalised world, migratory movements is continuously shaping the countries all over the world. Some countries like India and Ireland, which set the example of economic development and social integration, have the positive impact of the migration by globalisation and some countries like USA, which recently witness racism, xenophobia and discrimination have the negative impact on the migrants. It does not mean India do not face fragmentation and USA do not have cohesion. USA have many stories which show successful integration process, that facilitated the lives of immigrant communities, but being a developed country it still suffers from cultural alienation. In these countries, borders are built within borders to create cultural divides that do not allow people to integrate. Recently, this problem has become more prominent due to the rise of terrorism, clash of cultures in the world, leading to the glorification of stereotypes. People are becoming less accepting towards anyone who does not belong to their region. Migration does not stop after people move from one place to another place. The main question start after that ‘now what’ they will do. That is why this topic needs to be discussed thoroughly in order to find better solutions. This paper will begin with an analysis of different approaches to Migration, discuss the target groups for integration policies, provide indicators of the current situation of migrants and proceed to an analysis of integration tools: legislation, social policies and participatory processes. It will focus not only on the impact of migration but also on social integration, mix culture like indo-western culture in a comparative basis.

Ekta meena

With the emergence of HR Analytics in organizations; gathering, interpreting, and measuring of HR data has become easy. HR Analytics act as a tool which is a combination of statistical techniques that enable collection, interpretation, measurement, and forecasting of data. HR analytics enlightens solution to the organizational problems and make accurate decisions. HR analytics hence aligns HR strategy with overall business strategy to obtain a competitive advantage. HR analytics has passed through phases of measuring the Sub HR functions. HR Analytics provides various opportunities to business as it forecasts workforce requirements, enables HR to achieve corporate goals, and improve organizational performance which helps businesses in finding success. Despite the success, the business faces some big challenges like data governance, skill gap among employees, top management support, and many other such challenges in implementing and using the HR Analytics tool in business. Various research scholars have discussed HR analytics from so many years. So many papers have come focusing on the conceptual part of HR analytics, past present and future scenario of HR analytics, acceptance of HR analytics in organizations, the extent of its utility, rise of HR analytics, and various other related studies. This paper aims to find out the challenges and opportunities faced by the business firm in implementing HR analytics as a tool in organizations. This study also gives the theoretical concept of HR analytics based on secondary data collected from previous research papers, journal of the year 2016- 2019 given by various research scholars, blogs, and websites that provide HR analytics recent data. The study will provide the pros and cons of implementing and using HR analytics.

Mamta gaur

Vigna mungo (L.) Hepper belongs to the family Papilionaceae. It is an erect, hairy annual plant with long, twining branches. The flowers are small and yellow in color, while the fruits are cylindrical. The pods are hairy containing 1-4 seeds per pod. Seeds are used as a nervine tonic and in urinary reflex disorder. The phytochemical analysis revealed the presence of flavonoids, saponins, tannins, alkaloids, vitamin C and steroids. Seeds possess antidiabetic, antioxidant and hypolipidemic properties. The present review provides updated information on its medicinal uses, phytochemistry and pharmacology.

Dr. salman ahmed

Background: Poverty and malnutrition are associated with the risk of developing tuberculosis (TB). Nutritional reintegration with anti-TB therapy may improve treatment success rate. Aim: To investigate the nutritional status of low-income pulmonary TB patients in relation to the different anti-TB treatment phases. Methods: Forty five pulmonary TB patients and 40 controls aged 19-54 years, receiving treatment at Infectious Disease Hospital, Calabar, Nigeria, between September 2018 and July 2019 were studied. Serum total protein, albumin, iron and vitamin A were determined by colorimetric and HPLC methods respectively. Height and weight were measured and BMI computed, and data analysed using Student’s t-test, ANOVA, and Pearson’s correlation at P<0 P=0.001).>0.05) respectively. Albumin and iron were significantly lower in CPAT-HIV compared with CPAT patients. Albumin correlated positively and significantly with iron (r=0.405, p=0.006) in TB patients. Conclusion: Tuberculosis is associated with decreased BMI, albumin, iron and vitamin A, and higher total protein, and globulin, suggesting that malnutrition may be associated with TB risk, poor treatment compliance and outcomes

Eworo raymond

Each student has different potentials from one another, because each person is indeed born with a variety of different talents and has brought out his or her own nature, namely good nature that encourages tawhid and other natural qualities in the form of various innate potentials such as talents, intellectual abilities and others. The research approach used is a descriptive qualitative approach with the type of case study. The techniques used are interviews, observation, and documentation. While the validity of the data used triangulation of techniques and sources. The results of this study indicate: (1) Mina talents at MI Miftahul Muna through recruitment where students choose and register themselves to take part in the extracurricular program. Such as: drumband, dance, qiroat, scout, Pencak Silat, Chess, Volleyball, football, hadrah, singing, fashion, culinary, and calligraphy. (2) Interest talent planning, namely: Learning Implementation Plan, preparing experts who are competent in their fields as well as students recruited through extracurricular registration. Except for the drum band in this case bringing in experts from outside. (3) Implementation of talent and interest development at Madrasah Ibtidaiyah Miftahul Muna Kesilir, which is carried out once a week every Friday unless the drumband is held on Fridays and Sundays and if you want to appear at certain events, you can adjust the trainer's schedule or not. (4) Supervision is carried out directly at the time of the activity and some is carried out in an indirect way such as in this drumband activity because it brings in a trainer and is reported to the Madrasah Head.

Educare: journal of primary education