Objectives: Improper and inappropriate use of antibiotics is one of the possible factors affecting the transmission of antibiotic resistance is Because Pseudomonas aeruginosa is one of the most serious pathogenic bacteria in hospital environments and resistant It is an antibiotic that causes problems in treatment. This study aims to determine multiple resistances Pseudomonas has been treated with antibiotics, arsenic and metals. Materials and Methods: In this study, 23 strains of Pseudomonas aeruginosa were isolated from clinical specimens. for review Resistance of these bacteria to penicillin antibiotics was used by Kirby-Bauer method. The minimum concentration C.I.M. (and minimum lethal concentrations (C.B.M.) of antibiotics and heavy metals (cadmium, mercury) and arsenate Tubal dilution, agar and growth were performed in agar plate, respectively. Results: In this study, the highest and lowest MIC values obtained in Pseudomonas aeruginosa for metals, respectively. * 8 and 3 cadmiums (0.6 and 4.9 μg / ml), mercury (<0.12 and 4 μg / ml) and arsenate (10 × were 256 μg / ml). Of 23 strains, 84% to the antibiotic carbonicillin, 63% to piperacillin and 100% to 103 Arsenic and cadmium were resistant. Also, 82.6% of the strains were resistant to mercury. Conclusion: The results of this study showed that Pseudomonas aeruginosa strains have multiple resistance to arsenic, metals and the antibiotics are car penicillin and piperacillin.

Amirhossein jahromi

This study was conducted to optimize the integration of solar-photovoltaic-distributed energy resources (SPVDERs) within the Nigerian power system networks using an AI-based Particle Swarm Optimization (PSO) Algorithm. By employing a mixed research method, primary and secondary data were gathered to calculate flow analysis, NR method's equations, PSO's position update model, particle swarm optimizer algorithm, and application modeling including Solar-PV DER modeling. The AI-based PSO algorithm design was developed for optimizing SPV-DER integration in Nigerian power system networks, and key parameters and variables that needed consideration were identified. The study also established how the performance of the AI-based PSO algorithm could be evaluated and compared with other optimization techniques for SPV-DER integration within Nigerian power system networks. The study's results showed that voltage limits were within acceptable ranges, and solar power contributions were estimated at 880.10MW with 46,718 panels needed. The study concluded and recommended that investing in AI-powered tools for efficient power distribution; monitoring and resource optimization for sustainable energy sources would optimize performance and unleash Nigeria's sustainable energy potential.

Fxintegrity publishing

Phycochemical and pharmacological studies were carried out on Ulva fasciata Delile. The ash content was found to be 20.4812 % dry weight, moisture content 14.5514 %, and total fat content as 0.1878% and 0.49341 %. Total carbohydrate was found to be 54.5301-54.2246% dry weight, phenolic content was found to be 0.022%, flavonoids were found to be 0.0313%, and tannins were 0.00003 %. Ulva fasicata showed central analgesic activity and significant anti-inflammatory activity at 400 mg/kg bw.

Dr. salman ahmed

Mobile pervasive environment interact with several devices at varying service ranges. The technical heterogeneity of pervasive environment is expected to increase the system flexibility and adaptability on modeling with context training phase. While working with context based training phase, time entity measure is considered as the significant issue. The evaluation of the services through numerous devices during training phase does not acquire an effective service monitoring on mobile pervasive environment. Mobile pervasive environment based information extraction fails to modify the patterns as activities change over time. To improve the flexibility of context training phase in mobile pervasive environment, an Active Context Source Discover Training Phase (ACSDTP) with Classifier Decision Tree Support (CDTS) mechanism is proposed in this paper. Our research work is to develop an effective modification (i.e., updation) of the pattern on training phase with real world context as per changes over time. Initially, the ACSDTP set up the available sensors in pervasive environment to work with the ever changing set of context users. The available sensors are maintained using the Active Discover process. Second, the CDTS mechanism is designed using weighted prediction for easy identification of context result on the training phase. Decision tree is operated separately using the learning techniques, where the identification is performed in a significant manner with minimal time factor. The learning process is performed to identify the inferred situations. Finally, the integration process is carried out to work with the complex association between the situations and sensor data in the mobile pervasive environment to achieve flexibility and adaptability factor. Experiment is conducted on factors such as time entity measure rate, precision ratio, and user context result determination level.

Dr h shaheen

Obsessive-compulsive disorder (OCD) is a mental disorder that causes repeated unwanted thoughts or sensations, or do something over and over again. It is affecting all ages in the world. It is unusual for symptoms to begin after the age of 35 and half of people develop problems before 20. This making university students a target of OCD. This study investigates the prevalence of symptoms of OCD and identifies possible risk factors among pharmacy students of University of Tripoli, Libya. 80 pharmacy students registered in the final academic year 2019/2020 were enrolled in this study. All the participants were females ranging of 22 to 24 years old of a same environmental background. This study is based on a validated questionnaire for screening of OCD as mentioned by the American Psychiatric Association without modification. A total of 63 students have returned the questionnaire (response rate, 78.8%). The study shows that OCD symptom is relatively common among pharmacy students. The most common symptoms are losing something of importance (71%) and checking things over and over or repeat actions many times to be sure they are done properly (63%). Among OCD symptoms, the most common associated trigger factors were stress and phobia which representing 62% of the participated students. This study indicates that pharmacy students are at risk of being susceptible to getting OCD. OCD affects academic performance and quality of student life, therefore, a psychological and health services for university students should be implanted.

Mediterranean journal of pharmacy and pharmaceutical sciences

Background: Hypertension (HTN) is defined as a blood pressure (BP) ≥140/90 mm Hg. The prevalence and mortality from HTN, globally and locally, have been on the increase since the 1980s. This study aimed to detect young adults (18-40 years) in Enugu State who are hypertensive, in order to raise the awareness that HTN is also common in young adults. Its early diagnosis and management could help to reverse the trend in the number of cases of HTN in Nigeria which had been predicted could hit 39.1 million by 2030 if the present trend is allowed to continue. Methods: Participants were administered with structured questionnaire. Their BPs, heights and weights were measured using sphygmomanometer, stadiometer and scale balance respectively. Data were analyzed as proportions, Pearson product moment correlations and Chi square tests using MaxStat (version 3.60) statistical software. Results: The overall prevalence of HTN was 21.3%; 20.7% in the 18-29 years age group; 25.9% in the 30-40 years age group; 24.3%, in males; and 20.3% in females. Pearson product moment correlation coefficient r between age and HTN=0.462, between sex and HTN=0.328, between family history and HTN = 0.513, between salt intake and HTN=0.613, between BMI and HTN=0.152, between physical activity and HTN=0.293, between smoking and HTN=0.308. Conclusions: HTN in young adults is more common than previously thought and if unmanaged in early life usually progresses to HTN later in life.

Emmanuel umegbolu

Human resource management refers to the process of employing people, training them, compensating, and developing policies and strategies to keep them (Storey, 2016). Personnel management is an administrative specialisation that focuses on hiring and developing employees to become valuable to the organisation (Bondarouk, Trullen, and Valverde, 2016). Management of personnel can be characterised as a satisfied workforce being achieved, used, and maintained (Sheehan, Garavan & Carbery, 2014). It constitutes an essential aspect of the management of employees in the organisation and their connection. According to Schroeder (2012, p.4), personnel management is achieved to help organisational, individual, and social goals, as the planning, organisation, offsetting, and maintaining of people. Vargas et al. (2018, p. 3052) add that personnel management is the element that primarily deals with human organisational resources. Management of personnel covers job, development, and compensation functions. In consultation with other departments, the personnel management performs these functions principally (Vargas et al., 2018, p. 3053)

Zamzam abdelazim

Newcastle Disease Virus (NDV) constitutes a major constraint to the poultry production system in Nigeria. This study was carried out to investigate the seroprevalence of NDV antibodies in local chickens (Gallus domesticus) slaughtered in five different live bird markets (LBMs) in Kaduna metropolis, Nigeria. Three hundred blood samples were collected and screened for antibodies against NDV using Haemagglutination Inhibition (HI). An overall seroprevalence rate of 23% (95%:CI18.5-28.0) was recorded in this study. Seroprevalence based on different LBMs revealed a higher prevalence of 28.3% (95% : Cl 18.0-40.7) in Sabo market, followed by Sokoto road market 26.7% (Cl:16.7-38.9), Kawo market 18.3% (95% Cl: 10.0-29.6), Railway market 13.3% (Cl:6.4-23.5), and the lowest prevalence was recorded in central market 11.7% (Cl:5.2-21.7). The difference in seroprevalence among the LBMs was not statistically significant (p > 0.05). Higher seroprevalence of NDV antibodies in female birds 30.5 % (Cl: 24.1-37.6) was recorded compared to male 13.9% (Cl: 8.3-21.4). The study indicated that NDV is endemic in the population. LBMs location had no significant influence on the seroprevalence of NDV in the study area. The difference in seroprevalence between sexes was statistically significant (p < 0.05). Therefore, this study demonstrated the need for a regular strategic vaccination programme against NDV in local chickens in Kaduna metropolis.

Bitrus inuwa

The number of institutions and enrollment in higher education continue their rapid growth, but the quality of this education remains uncertain. A small number of state subsidized institutions attract a thin top layer of talent from each year’s cohort. High selectivity of admission to these elite institutions provides a screen valued by potential employers. Domestic and foreign demand for the services of these few thousand students has created an inflated reputation of the overall quality of India’s higher education. The number of such graduates remains small relative to the population and the demands of India’s economy for educated manpower. Reliable estimates of value-added by higher education, beyond the screening value of admission to elite institutions, are needed to assess colleges and universities, and to guide educational policy. Graduate education the seed farm of higher education and scholarship continues in an alarming state of disarray with respect to both quality and quantity. Pressed by budgetary constraints, the government appears to have decided on profit-oriented privatization of higher education as the solution. Political and business classes, with significant overlap between the two, see higher education as a source of lucrative private returns on investment. There is little theoretical or empirical evidence that supports the prospects of success of a for-profit model in building quality higher education. Some recent proposals hold promise of radical reform and renovation, including regulatory restructuring. It remains unclear whether the government has the wisdom, determination, financing, and power to push reforms past the resistance from entrenched faculty and from the political and business classes. It’s absolutely true that the future and overall development of any country depends upon the fact that how educated its citizens are. Though, gaining a professional degree is not possible for everyone due to various reasons, but what actually matters is the basic education. That is, one should know how to read and how to write. India has shown significant improvement in education since 1947 until today. However, we believe that there is always some room for improvement in every field. So let us discuss 10 ways that can help us improve our education system. To strengthen the Indian Education System, an educational policy was adopted by the Indian Parliament in 1968. Education was made an important and integral part of the national development efforts. Our Government assumed full responsibility for the proper education of the children and adults. Hence, right to primary education or elementary education is now a fundamental right in India.

Dr gedam kamalakar

The research paper aims to find out the relevance of the existing support system for accelerating women entrepreneurship development and how these entrepreneurial support services of various Institutions expedite the process of social inclusion of women. The study has been conducted in the West Tripura District between January to August 2022. A total of 385 women entrepreneurs who were trained under government institutions were considered as the sample size. The primary data was collected directly from the field on basis of secondary information from Government Departments. The purposive sampling method has been deployed to identify the respondents for conducting the sample survey .

Md. abdur rahman choudhury

The share of renewable energy share in India's energy mix of India has been increasing recently owing to the promotion and implementation of various government policies that promote the use of renewable sources of energy, depleting fossil fuel levels, increasing fuel prices, and stringent laws for emission reduction worldwide. The increase in the use of solar-evacuated-tube-collector-based domestic water heating is the result of this transition from conventional to nonconventional sources of energy. The recent urban agglomeration is challenging to install these solar water heaters in every household because the roof space is limited. Space reduction can be achieved by reducing the collector area by varying the diameter of the evacuated tubes. This study used a single tube and tank arrangement model with a fixed inclination to achieve a thermosyphon effect in a solar water heating system with three different diameter configurations of 48 mm, 54 mm, and 72 mm, with a tube measuring 1800 mm in length. Thermal assessment of the thermosyphon-based evacuated tube-solar water heater using the ANSYS CFD simulation software involves measuring the temperature at three different positions in the tank to study the thermosyphon initialization. This study signifies that the 72-mm-diameter evacuated tube is more capable of initializing the thermosyphon effect in the system. Nevertheless, the final temperature of the system is better achieved in the 48-mm-diameter evacuated tube

Swapnil ratnakar mane

Pain according to WHO has been one of the greatest issues to plague man, in the bid to handle this issue of pain, man has sought to look for other means to reduce pain to its bare minimum. This study is aimed at investigating the analgesic activity of the methanolic extract of the African weaver ant using acetic acid-induced writhing, hot plate method, and formalin-induced pain models in Swiss mice. In the acetic acid test, the methanolic extract of Oecophylla longinoda (OL) was administered orally at 200 and 400 mg/kg body weight while aspirin was administered at 100 mg/kg and tween 80 served as standards. In the hot plate and formalin models, the extract was administered orally at two doses of 200 and 400 mg/kg while pentazocine at 10 mg/kg and tween 80 at 10 mg/kg served as standards. The methanolic extract of OL exhibited significant analgesic activity in all the models, with none less than the standard significant difference (p < 0.05) by increasing the reaction time of the mice after treatment in comparison to the control. The 400 mg/kg extract in the acetic acid-induced writhing response has a percentage inhibition of 52.7%, which shows how well the extract inhibits pain in mice. The methanolic extract significantly reduced pain response in mice, with a p-value of 0.03, 0.02, and 0.001 in all the test models, respectively. OL increased the pain threshold over time and significantly reduced the writhing response that mice experience from acetic acid. Furthermore, pretreatment with OL significantly and dose-dependently decreased the early and late phases of formalin-induced pain in mice. Thus, these findings suggest that the methanolic extract of OL acts on central and peripheral pain pathways.

Mediterranean journal of pharmacy and pharmaceutical sciences

Capsicum has been an essential part of the diet for centuries and has been widely used traditionally for ailments. The objective of the present analysis was to determine the diuretic and antidiarrheal potentials of four variations of Capsicum annum L. fruits available in the local market of Karachi, Pakistan. It belongs to the family Solanaceae, and extracts were prepared in 95% ethanol and given in 200 and 400mg/kg doses. The activity correlated with commonly used diuretics and anti-diarrheal, reinforcing its conventional use. To confirm its activity, fruit extracts were evaluated for anti-diarrheal properties in castor-oil-induced diarrhoea. The diuretic activity of the 95% ethanolic extracts of Capsicum annum L. was assessed based on diuresis of 24 hr. collected through a metabolic cage. Urinary excretion of water and electrolytes (Na+ and K+) is significantly increased by the standard diuretic drug furosemide, which is comparable with the extract. The anti-diarrheal effects of 95% ethanolic extracts of Capsicum annum L. were examined by castor oil-induced diarrhoea. All varieties of Capsicum annum L. significantly inhibited the number of defecations.

Dr. salman ahmed

The current study explored the anti-emetic activity of six aromatic medicinal plants viz Carissa carandus L.. Cichorium intybus Cinnamomum tamala L.. Lallemantia royleana Benth. Matricaria chamomilla L., and Piper metysticum G. Forst . Anti-emetic activity was assessed using a chick as an anti-emetic model. The ethanol extracts of these plants were administered at 150 mg/kg BW orally. Lallemantia royleana and Piper metysticum showed a significant (P <0.001 ) decrease in retches induced by copper sulphate pentahydrate given orally at 50 mg/kg BW. Domperidone was given at 100 mg/kg as a reference drug.

Dr. salman ahmed

ABSTRACT Objective: The objective of the present study was to develop an HPLC analytical method and to perform in vivo study of Emblica officinalis and Aegle marmelos extracts for antioxidant and antidiabetic activity. Methods: The phytochemical analyses, total phenolic content (TPC), TLC, DPPH assay were performed for freeze-dried Emblica officinalis fruits aqueous extract (EOFAE) and Aegle marmelos leaves ethyl acetate extract (AMLEAE). The active constituents present in both extracts were estimated by using HPLC system having Hibar® Results: Tannins, saponins, carbohydrate, glycosides are found in EOFAE; coumarins and flavonoids are found in AMLEAE and quinones, phenols are present in both extracts. The values of TPC present in standard gallic acid, EOFAE and AMLEAE were found to be 485.7, 315.6, 300.7 mgGAE/g, respectively. R C18 column [250 x4.6 mm, 5 µm] and UV detector (264 nm). A gradient mobile phase (acetonitrile and water with 0.1% trifluoroacetic acid) was used at a flow rate of 0.8 ml/min. In vivo antioxidant, antidiabetic activity of both extracts was conducted on male albino Wistar rats for 21 d in streptozotocin-induced diabetic rats (42 rats; n=6). The antidiabetic activity was measured by blood glucose level and biochemical parameters i.e. total cholesterol, triglycerides and total protein. Oxidative stress was measured by antioxidant biomarkers i.e. SOD, GSH, lipid peroxidation by thiobarbituric acid reactive substances method on the liver of the experimental rat. f Conclusion: The present study showed that the EOFAE and AMLEAE treated group III with (EOAM) low dose of 500 mg/kg body weight has potent antioxidant and antidiabetic activity. values obtained by TLC of EOFAE and AMLEAE were found to be 0.41 and 0.50, respectively. The values of % inhibition shown by EOFAE and AMLEAE in DPPH assay were found to be 97.8%±2 and 95.2%±2, respectively. The values of retention time of EOFAE and AMLEAE by HPLC analysis were found to be 4.59 and 5.28 min, respectively. Histopathological examination of the liver was revealed that low dose EOAM (containing of EOFAE 250+AMLEAE 250 mg/kg body weight) administered once a daily for 21 d showed significant activity (P˂0.001) with biochemical parameters and antioxidant biomarkers. Keywords: Emblica officinalis, Aegle marmelos, Antioxidant, Antidiabetic activity, streptozotocin, HPLC

Snehal

Nine fruit morphological traits were studied in ten stands of Jatropha curcas spread in eight forest divisions of Uttarakhand. Variation was examined at stand level as well as at tree level. Significant differences were found among stands for fruit length, fruit diameter, pericarp weight per fruit, seed: fruit weight ratio, kernel: fruit weight ratio and pericarp: fruit weight ratio traits while all morphological traits showed significant differences among trees within stands. The estimation of the variance components, however, revealed that the fruit traits, especially weight traits viz. fruit weight, total seed weight per fruit and total kernel weight per fruit have negligible contribution from stands and small contribution from trees. Maximum variation was found among fruits within trees (i.e. at fruit level or error). Pericarp weight per fruit and fruit ratio traits (i.e. seed: fruit weight ratio, kernel: fruit weight ratio and pericarp: fruit weight ratio) were affected to small extent by stand per se. The repeatability of all fruit traits at tree level were also low to moderate (0.105 to 0.278)

Kshitij malhotra

Pharmacists stand alongside with other professionals in representing essential healthcare during health emergencies such as COVID-19 pandemic. The present study seeks to explore the behavior and attitude of community pharmacists across various pharmacies throughout this pandemic towards the safety of workplace environment for staff and patients. An online questionnaire has been prepared and distributed to 145 community pharmacies during March to May, 2020. The collected results and data showed that community pharmacists in Libya have a good knowledge and adherence to preventive and protective measures published by FIP, WHO and other health-related organizations to protect themselves and society from infection. The pharmacist role in educating and information provision of the current disease and its management is still going on regardless the pandemic. A negative evaluation to the government support during the pandemic is clear from participant's replies. In Conclusion, this study looks forward to disclosing the current activities undertaken across various community pharmacy settings concerning safety of the workplace environment for both staff and patients. A clear and relatively realistic picture of the extent of commitment and knowledge of pharmacists of the necessary aspects needed to deal with this pandemic within community pharmacies is suggested. The extent of community pharmacist's knowledge, readiness and speed of their response to such a pandemic have been identified.

Mediterranean journal of pharmacy and pharmaceutical sciences

The research into plant is used to search for new agents with pharmacological activities. This study seeks to evaluate the effects of the palm leaf methanolic extract against nephrotoxicity, hepatotoxicity, and weight loss induced by chemotherapeutic drug doxorubicin in a rat’s model. Five groups of rats (n= 4 in each group) were treated with or without doxorubicin (3.0 mg/kg/day, ip) and with palm leaf methanolic extract (400 mg/kg/day or 1200 mg/kg/day, po), followed by evaluation of renal and hepatic biochemical markers. The findings obtained indicated that palm leaf methanolic extract exerts protective effects against doxorubicin-induced nephrotoxicity and hepatotoxicity. Doxorubicin significantly elevated renal function markers, namely creatinine, uric acid and urea, however, these biomarkers remained within normal levels after treatment with palm leaf methanolic extract (400 mg/kg/day) as compared to the control group. Treating the rats with doxorubicin and palm leaf methanolic extract at doses 400 mg/kg/day and 1200 mg/kg/day, counteracts the doxorubicin-induced elevation of serum creatinine and uric acid compared to the doxorubicin group. Doxorubicin also significantly increased hepatic function tests namely alanine and aspartate aminotransferase, gamma-glutamyl transferase, and bilirubin as compared to the control group. In addition, treating the rats with palm leaf methanolic extract doses and doxorubicin caused a significant decrease in the serum levels of hepatic markers compared to the doxorubicin group. Doxorubicin treatment resulted in a weight loss of 34.1%, the weight loss caused by doxorubicin was prevented by treating the rats with the extract at 1200 mg/kg/day as compared to their baseline body weight. Thus, the results of the current study suggest that the active constituents present in the palm leaf methanolic extract have a protective effect against hepatotoxicity, nephrotoxicity and weight loss-induced by doxorubicin.

Mediterranean journal of pharmacy and pharmaceutical sciences

The rate of oxygen consumption was measured in mercury chloride treated freshwater fish, cyprinus carpio for 96h and compared to control group. The present investigation showed that average oxygen rate was decreased in all treated animal as compared to controlled group. Behavioural changes was also recorded in both concentration. The behavioural alterations observed like surfacing, erratic movement, increased mucous secretion, decreased opercular movement and loss of balance. The present study revealed that, mortality rate increased with increases in concentration.

.vijay digambar suryawanshi

Lexical and structural levels of language abound ambiguities that are good source of humor. Consequently, violations of the maxims of conversation are leeway to induce humor in any type of discourse. Adding these two precepts and considering pragmatics as its foundation became the bases in analysing the top-grossing films of Vice Ganda. It sought to identify the verbal linguistic jokes and ambiguities present in the top-grossing films of Vice Ganda; determine on how these ambiguities create devaluation of Grice’s maxims of conversation; and determine on how the ambiguities in verbal linguistic jokes and devaluation of Grice’s maxims of conversation were used as ingredients in Vice Ganda’s top-grossing films. Discourse analysis was used in the study and the analytical framework to induce humor by Taghiyev (2018) was used in analysing the corpora. A priori coding was used to identify the recurring ambiguities and devaluation of maxims in the films. Findings show that lexical-semantic and structural-syntactic ambiguities were present in the films. It was intentionally used in order to create humorous effect in the dialogues of the films. Moreover, the devaluation of the maxims of conversation quietly and unostentatiously, opting out, coping with a clash between maxims, and flouting was deemed an effective ingredient to make the films become comical and appealing to the audience.

Darrel ocampo