Dr. Salman Ahmed
Therapeutic potential of marine peptides in malignant melanoma
Journal title : Environmental Research
Publisher : Elsevier BV
Print ISSN : 0013-9351
Page Number : 115771
Journal volume : 227
294 Views Reviews Article
Malignant melanoma is the most dangerous type of skin cancer. It is becoming more common globally and is increasingly resistant to treatment options. Despite extensive research into its pathophysiology, there are still no proven cures for metastatic melanoma. Unfortunately, current treatments are frequently ineffective, costly, and have several adverse effects. Natural substances have been extensively researched for their anti-MM capabilities. Chemoprevention and adjuvant therapy with natural products is an emerging strategy to prevent, cure or treat melanoma. Numerous prospective drugs are found in aquatic species, providing a plentiful supply of lead cytotoxic chemicals for cancer treatment. Anticancer peptides are less harmful to healthy cells and cure cancer through several methods, such as altered cell viability, apoptosis, angiogenesis/metastasis suppression, microtubule balance disturbances and targeting lipid composition of the cancer cell membrane. This review addresses marine peptides as effective and safe treatments for MM and details their molecular mechanisms of action.
Article DOI & Crossmark Data
DOI : https://doi.org/10.1016/j.envres.2023.115771
Article Subject Details
- Detection clinics and melanoma
- Melanoma surveillance
- Oncology
- Oncology treatment
- Pharmacognosy
- Pharmacology
- Pharmacology and toxicology
Article Keywords Details
- Antimetastatic
- Antimitotic
- Apoptosis
- Cell cycle arrest
- Immunostimulant
- Membrane-lipid therapy
- Anticancer marine peptides
Article File
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