Much Ilham Novalisa Aji Wibowo Profile Much Ilham Novalisa Aji Wibowo

Systematic review: determinants influencing medications adherence of type 2 diabetes patients in indonesia

  • Authors Details :  
  • Much Ilham Novalisa Aji Wibowo,  
  • Nanang Munif Yasin,  
  • Susi Ari Kristina,  
  • Yayi Suryo Prabandari

Journal title : Media Penelitian dan Pengembangan Kesehatan

Publisher : Badan Penelitian dan Pengembangan Kesehatan

Print ISSN : 0853-9987

Page Number : 281-300

Journal volume : 31

Journal issue : 4

163 Views Reviews Article

Compliance with pharmacological therapy is the primary key to treating diabetes, but it has not received full attention from clinicians. Several systematic reviews of compliance factors have been conducted in several regions of the country. However, it does not feature studies from Indonesia. This study aims to systematically review the factors that can influence adherence to diabetes mellitus (DM) medication in Indonesia. A systematic literature review was conducted by searching the National (Garuda and Sinta) and International (PubMed and Science Direct) journal databases. Research that met the inclusion criteria was published from January 2011 to December 2020. The quality of the study was assessed using the SQAT guidelines. The research reporting method uses the PRISMA guidelines. Compliance factors are classified based on the domain of compliance factors, according to the World Health Organization (WHO). A total of 370 scientific research articles from the Garuda database (n=36); Science Direct (n = 108); PubMed (n = 18); Sinta (n= 208). Three hundred forty-one research articles were excluded, 29 full-text screening articles, and 16 research articles met the inclusion criteria for analysis. Factors that influence adherence to taking diabetes medication are social and economic (income, education level, and occupation), factors of personnel and health systems (health workers), factors of patient therapy (amount of diabetes medication, frequency of taking medication, and drug products), factors patient's disease (blood sugar levels, disease duration), patient factors (gender, emotional factors, social support, level of knowledge, and treatment satisfaction), and disease management factors (pharmacy counseling and education). Factors that influence adherence to taking DM medication in Indonesia are very diverse and are multi-factor. These factors can serve as relevant intervention targets. Clinicians must consider adjusting the frequency of taking medication and providing social support to DM patients.

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