Brinda Elangovan

Review on the cardioprotective role of pinocemrin in atherosclerosis, myocardial infarction and related vascular-myocardial remodeling

• Authors Details :  
• Brindha Elagovan And Anupama Baby Chandrasekharan

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Cardiovascular diseases represent a formidable global health challenge, standing as the foremost cause of both mortality and morbidity. Atherosclerosis and myocardial infarction, as primary contributors to this epidemiological burden, underscore the urgent need for effective therapeutic interventions with minimal side effects. Natural compounds derived from plants have emerged as promising candidates, given their enhanced efficacy and reduced adverse effects. Phytochemicals, in particular, have garnered attention for their potential as alternative therapeutic agents. This review delves into the cardioprotective potential of pinocembrin (5,7-Dihydroxy flavanone), a compound extracted from various plants and honey. Renowned for its antioxidant and anti-inflammatory properties, pinocembrin demonstrates significant cardioprotective effects through the modulation of diverse signaling pathways. Atherosclerosis and myocardial infarction entail intricate cellular mechanisms involving oxidative stress, inflammatory responses, cellular remodeling, and programmed cell death. Pinocembrin, by targeting key factors within these pathways, exhibits cardioprotective actions. While existing research underscores its effectiveness, further investigations are warranted to elucidate the impact of pinocembrin on additional cardiovascular conditions and explore novel molecular targets, thus paving the way for future advancements in therapeutic interventions.

Article Subject Details

• Animal science
• Biochemistry
• Biological Sciences

Article Keywords Details

• atherosclerosis
• cardioprotective role
• MI
• Pinocembrin

Article File

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