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Nutritional background of low-income pulmonary tuberculosis patients on anti-tuberculosis therapy at infectious disease hospital, calabar, nigeria: a case-control study

  • Authors Details :  
  • Eworo,  
  • Nsonwu-anyanwu,  
  • Fabian,  
  • Akpan,  
  • Udo

Journal title : Open Access Research Journal of Science and Technology

Publisher : Open Access Research Journals Publication

Online ISSN : 2782-9960

Page Number : 070-079

Journal volume : 5

Journal issue : 1

509 Views Original Article

Background: Poverty and malnutrition are associated with the risk of developing tuberculosis (TB). Nutritional reintegration with anti-TB therapy may improve treatment success rate. Aim: To investigate the nutritional status of low-income pulmonary TB patients in relation to the different anti-TB treatment phases. Methods: Forty five pulmonary TB patients and 40 controls aged 19-54 years, receiving treatment at Infectious Disease Hospital, Calabar, Nigeria, between September 2018 and July 2019 were studied. Serum total protein, albumin, iron and vitamin A were determined by colorimetric and HPLC methods respectively. Height and weight were measured and BMI computed, and data analysed using Student’s t-test, ANOVA, and Pearson’s correlation at P<0 P=0.001).>0.05) respectively. Albumin and iron were significantly lower in CPAT-HIV compared with CPAT patients. Albumin correlated positively and significantly with iron (r=0.405, p=0.006) in TB patients. Conclusion: Tuberculosis is associated with decreased BMI, albumin, iron and vitamin A, and higher total protein, and globulin, suggesting that malnutrition may be associated with TB risk, poor treatment compliance and outcomes

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DOI : https://doi.org/10.53022/oarjst.2022.5.1.0044

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