Aneesh Basheer

Melioidosis: distinctive clinico-epidemiological characteristics in southern india

• Authors Details :  
• Aneesh Basheer,  
• Nayyar Iqbal,  
• Sheeladevi C,  
• Reba Kanungo,  
• Ravichandran Kandasamy

Journal title : Tropical Doctor

Publisher : SAGE Publications

Online ISSN : 1758-1133

Page Number : 004947552094369

702 Views Research reports

As it is increasingly being reported from India, we carried out a prospective study of patients with culture-proven melioidosis from south India, examining clinical, laboratory features, epidemiological data, risk factors, treatments, outcomes at three and six months, and factors associated with mortality.Between 2014 and 2018, 31 cases were identified. Diabetes (83.9%) and alcohol abuse (58.1%) were common risk factors. Musculoskeletal, skin and soft tissue manifestations together constituted 48.4% of presentations, while 29% had pneumonia. During the intensive phase, 74.2% received one of three recommended antibiotic regimes, but 51.6% did not receive continuation treatment. Pneumonia and lack of continuation treatment were independently associated with a high mortality of 25.8%. Hot spots for melioidosis exist in India, and there is considerable diversity of presentation, including skin, soft tissue, musculoskeletal and neurological involvement. High rates of bacteraemia are shown.

Article DOI & Crossmark Data

DOI : https://doi.org/10.1177/0049475520943698

Article Subject Details

• Antibiotics
• Blood cultures
• Clinical microbiology
• Health sciences
• Infective arthritis
• Lung diseases
• Medical microbiology

Article Keywords Details

• burkholderia pseudomallei
• Epidemiology
• Meningits
• Mortality
• Pneumonia

Article File

Full Text PDF

---

---

Article References

• (1). 10.1038/529290a
• (2). 10.1016/S0035-9203(08)70002-6
• (3). 10.1038/nmicrobiol.2015.8
• (4). 10.1371/journal.pntd.0000900
• (5). 10.1371/journal.pntd.0005923
• (6). 10.3201/eid1707.101069
• (7). 10.1186/s12879-016-1583-2
• (8). 10.1016/j.ijid.2012.02.012
• (9). 10.1016/S0035-9203(08)70005-1
• (10). 10.1093/cid/cir808
• (11). 10.3201/eid2502.170745
• (12). 10.3390/tropicalmed3020040