Dr. Salman Ahmed

Hypotensive activity of melilotus officinalis (l.) pallas

• Authors Details :  
• Muhammad Sohail Anwer,  
• Sumbul Shamim,  
• Salman Ahmed,  
• Muhammad Mohtasheemul Hasan,  
• Iqbal Azhar

Journal title : European Journal of Medicine. Series B

Publisher : Academic Publishing House Researcher

Print ISSN : 2409-6296

Page Number : 80-85

Journal volume : 3

Journal issue : 2

306 Views Original Article

Melilotus officinalis (L.) Pallas. is used traditionally to treat hypertension and chronic venous insufficiency. The high prevalence of hypertension and the side effects of antihypertensive drugs potentiate us to evaluate Melilotus officinalis. The hypotensive effect of Melilotus officinalis butanol fraction (MOBF) was investigated in anaesthetised normotensive rats. The doses of 60, 80 and 100 mg/ kg, i.v., produced a significant (P<0.05) decrease in blood pressure. The statistically non-significant reduction in blood pressure was shown by 20 and 40 mg/ kg, i.v. These results suggest that Melilotus officinalis exhibited a hypotensive effect in normotensive rats. However, further evaluation of compound-related activity is required.

Article DOI & Crossmark Data

DOI : https://doi.org/10.13187/ejm.s.b.2015.3.80

Article Subject Details

• Biological Sciences
• Health sciences
• Medicine
• Pharmacognosy
• Pharmacology
• Pharmacology and toxicology

Article Keywords Details

• Melilotus
• Pharmacognosy
• Antihypertensive
• Hypotensive
• Pharmacology
• Pharmacy
• Phytomedicine

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