Dr. Salman Ahmed

Diuretic and anti-diarrheal potential of four fruit extracts of capsicum annum l

• Authors Details :  
• Nimra Mazhar,  
• Muhammad Mohtashem Ul Hasan,  
• Sadia Ghousia Baig,  
• Salman Ahmed,  
• Razia Jaffery,  
• Rahila Ikram

259 Views Original Article

Capsicum has been an essential part of the diet for centuries and has been widely used traditionally for ailments. The objective of the present analysis was to determine the diuretic and antidiarrheal potentials of four variations of Capsicum annum L. fruits available in the local market of Karachi, Pakistan. It belongs to the family Solanaceae, and extracts were prepared in 95% ethanol and given in 200 and 400mg/kg doses. The activity correlated with commonly used diuretics and anti-diarrheal, reinforcing its conventional use. To confirm its activity, fruit extracts were evaluated for anti-diarrheal properties in castor-oil-induced diarrhoea. The diuretic activity of the 95% ethanolic extracts of Capsicum annum L. was assessed based on diuresis of 24 hr. collected through a metabolic cage. Urinary excretion of water and electrolytes (Na+ and K+) is significantly increased by the standard diuretic drug furosemide, which is comparable with the extract. The anti-diarrheal effects of 95% ethanolic extracts of Capsicum annum L. were examined by castor oil-induced diarrhoea. All varieties of Capsicum annum L. significantly inhibited the number of defecations.

Article Subject Details

• Health Science
• Medicine
• Pharmacognosy
• Pharmacology
• Pharmacology and toxicology
• Pharmacy

Article Keywords Details

• anti-diarrheal
• bell pepper
• capsaicin
• diuretic
• Capsicum

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