Dr. Salman Ahmed

Antiemetic and anti-inflammatory activity of leaves and flower extracts of luffa cylindrica (l.) roem

  • Authors Details :  
  • Kanwal Waseem Khan,  
  • Syed Waseemuddin Ahmed,  
  • Salman Ahmed ,  
  • Mohammad Mohtasheemul Hasan

203 Views Original Article

Ethanol and hexane extracts of the leaves and male flowers of Luffa cylindrica were evaluated for antiemetic and anti-inflammatory effects using chick emesis model and carrageenan-induced rat paw oedema. The antiemetic effect was observed at 150 mg/kg body weight, whereas the anti-inflammatory effect was observed at doses of 500,750 and 1000 mg/kg body weight orally. Chlorpromazine 150 mg/kg and indomethacin 10mg/kg orally were used as standard antiemetic and anti-inflammatory drugs. The antiemetic effect was determined by calculating the mean decrease in the number of retching compared to the control group after 10 minutes of copper sulfate (50 mg/kg orally) administration. The degree of paw oedema of all the groups was measured using a plethysmometer at the 5th hour of carrageenan (1% w/v) administration. All extracts except hexane extract of leaves exhibited statistically significant (P<0.001) antiemetic and except hexane extract of flower, all extracts exhibited statistically significant (P<0.05) anti-inflammatory effects.

Article Subject Details


Article Keywords Details



Article File

Full Text PDF





More Article by Dr. Salman Ahmed

Analgesic and antiemetic activity of cleome viscosa l.

The seeds of cleome viscosa are used in traditional systems of medicine for the treatment of many diseases in asia. this study evaluated fixed oil from the seeds of cleome viscosa...

Toxicity assessment of mucuna pruriens linn seeds

Plants have been used as medicine for the treatment of diseases for thousands of years. these herbal remedies, although natural, can cause some serious damaging effects on the vita...

Antiemetic activity of some aromatic plants

The current study was conducted to explore the antiemetic activity of ten aromatic medicinal plants viz., carissa carandus l. (fruits), chichorium intybus l (flowers), cinnamum tam...

Anti-emetic activity of some leguminous plants

Crude methanol extracts of the leaves of adenanthera pavonina l., peltoforum roxburghii l, prosopis cineraria l., and prosopis juliflora dc., were evaluated for anti-emetic activit...